$213 Cheap flight deals from Pereira (CLO) to Panama City (PTY)

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This Weekend's Flight Deals from Pereira to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 12 - Sun, Sep 13
CLO
Alfonso Bonilla Aragon Intl.
PTY
Tocumen Intl.
$364 Roundtrip, found 1 day ago
$364
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Sep 12 from Alfonso Bonilla Aragon Intl. to Tocumen Intl., returning Sun, Sep 13, priced at $364 found 1 day ago

Airfares from $213 One Way, $363 Round Trip from Pereira to Panama City

Prices starting at $363 for return flights and $213 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 8 - Mon, Sep 14
CLO
Cali
PTY
Panama City
$363 Roundtrip, found 3 days ago
$363
Roundtrip
found 3 days ago
Select Copa flight, departing Tue, Sep 8 from Cali to Panama City, returning Mon, Sep 14, priced at $363 found 3 days ago
Sat, Sep 12 - Sun, Sep 13
CLO
Cali
PTY
Panama City
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Sep 12 from Cali to Panama City, returning Sun, Sep 13, priced at $375 found 1 day ago
Sat, Sep 12 - Sun, Sep 13
CLO
Cali
PTY
Panama City
$401 Roundtrip, found 1 day ago
$401
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Sep 12 from Cali to Panama City, returning Sun, Sep 13, priced at $401 found 1 day ago
Thu, Jan 21 - Thu, Jan 28
CLO
Cali
PTY
Panama City
$423 Roundtrip, found 3 days ago
$423
Roundtrip
found 3 days ago
Select avianca flight, departing Thu, Jan 21 from Cali to Panama City, returning Thu, Jan 28, priced at $423 found 3 days ago
Thu, Oct 22 - Thu, Oct 29
CLO
Cali
PTY
Panama City
$423 Roundtrip, found 2 days ago
$423
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Oct 22 from Cali to Panama City, returning Thu, Oct 29, priced at $423 found 2 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City
4.0-star property

Decapolis Hotel Panama City

8.6/10 Excellent! (1,716 reviews)

Oct 30 - Nov 5

6 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $1,014, price is now $609 per person
$609
per person
found 12 hours ago
My son and I stayed one night at the Decapolis Hotel, and while the property itself is impressive, the overall experience was mixed. The hotel is immaculately clean, centrally located, and offers great views of the city. We enjoyed the modern amenities, including the large pool, glass elevator, and the convenient skywalk that connects directly to a shopping center. Unfortunately, the service did not match the quality of the facilities. Staff members were curt and unhelpful, and when we asked questions, we were often shrugged off or redirected without explanation. Other guests were assisted while we were ignored, which left a negative impression. The hotel’s open‑lobby design also created a major issue: an event took place late into the night, and the noise carried all the way up to the rooms. We weren’t able to sleep until it ended past midnight. Check‑in was another challenge. Tour groups arrived at the same time, and although two staff members were present, only one was willing to check us in. The other employee was checking in random guests but refused to assist us, pointing us toward the long tour‑group line instead. Checkout, however, was quick and easy. Overall, the hotel has excellent facilities and a great location, but the service and noise issues significantly impacted our stay.

Reviewed on Sep 5, 2026

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9.2/10 Wonderful! (1,001 reviews)

Oct 30 - Nov 5

6 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,993, price is now $809 per person
$809
per person
found 12 hours ago
Clean rooms, great breakfast. Great air conditioning, small small pool. Great location. Friendly staff.. lots to do near by. Stairs and elevators

Reviewed on Sep 5, 2026

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,692 reviews)

Oct 30 - Nov 5

6 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $1,511, price is now $702 per person
$702
per person
found 12 hours ago

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More About Flying To Panama City from Pereira

Route Information for Flights from Pereira to Panama City

Origin Airport IATA Code
CLO
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Pereira to Panama City

Find fantastic fares on domestic and international flights that suit your travel requirements and budget needs by heading to Orbitz. Orbitz has your cheap air tickets for flights from Pereira to Panama City.

Flights from Pereira to Panama City at bargain prices

Budgeting and hidden costs should be the least of your concerns when planning a trip. Your priority should be planning all the things you want to do during your stay. With our low fares on Pereira to Panama City flights, you know you are getting the best deal for your vacation or business trip budget—and not incurring hidden costs or paying for over-priced tickets offered by some airlines. We want to help you enjoy your trip the way you deserve.

Remain up-to-date on your flights from Pereira to Panama City

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Orbitz booking discounts for Pereira to Panama City flights

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Frequently asked questions

Are there non-stop flights from Pereira to Panama City?
There sure is. You can fly directly from Pereira to Panama City with Copa Airlines. It's the only airline with nonstop services from CLO to Panama City (PTY-Tocumen Intl.).
What is the shortest flight from Pereira to Panama City?
It can take as little as 1 hour and 29 minutes to jet from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY). Settle in and enjoy the ride, because you'll be landing before you know it.
What airlines fly from Pereira to Panama City most frequently?
If you're looking for the airline that offers the most flights from Pereira to Panama City, Copa Airlines is the top pick. This trusted airline operates 104 monthly flights along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.