Selected fares from Portland to San Francisco

Portland to San Francisco Intro 32

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Map

Save more with San Francisco Flight + Hotel packages

Hotels in San Francisco

See all 426 Hotels in San Francisco
Park Central Hotel San Francisco, a Starwood Hotel
Park Central Hotel San Francisco, a Starwood Hotel
50 3rd St, San Francisco
4.0 out of 5.0
4.0 out of 5 (206 reviews)

Located in the heart of the South of Market district (SoMa), Park Central Hotel San Francisco (formerly Westin Market Street) is across from Yerba Buena Gardens ...

$241

$241
Hotel Nikko San Francisco
Hotel Nikko San Francisco
222 Mason St, San Francisco
4.0 out of 5.0
4.2 out of 5 (355 reviews)

The Asian-inspired Hotel Nikko San Francisco is located downtown, a 4-minute walk from Union Square and the designer shops of Westfield San Francisco Centre. ...

$199

$199
Stanford Court San Francisco
Stanford Court San Francisco
905 California Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (236 reviews)

Guests can indulge in high-end shops like Prada and Tiffany & Co at Union Square, 4 blocks away. Chinatown is 5 minutes on foot, and the American Conservatory ...

$219

$219
Pier 2620 Hotel Fisherman's Wharf
Pier 2620 Hotel Fisherman's Wharf
2620 Jones Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (125 reviews)

Located in the heart of San Francisco, this hotel is within a 10-minute walk of Ripley's Believe It Or Not Museum, Wax Museum at Fisherman's Wharf, and Ghirardelli ...

$220

$220
Clift
Clift
495 Geary St, San Francisco
4.0 out of 5.0
4.6 out of 5 (11 reviews)

Old-world elegance is suffused with modern glamour in this historic San Francisco hotel 2 blocks from Union Square, a half-mile from the Financial District, ...

$229

$229
Hilton San Francisco Union Square
Hilton San Francisco Union Square
333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (498 reviews)

Iconic, AAA 4-Diamond hotel a few steps from Union Square, Cable Car station, theatre district, BART, Chinatown, SFMOMA, and Moscone Center. Upgraded rooms offer ...

$206

$206
Handlery Union Square Hotel
Handlery Union Square Hotel
351 Geary St, San Francisco
3.5 out of 5.0
4.1 out of 5 (304 reviews)

A half-block from cable cars, this hotel is 2 blocks from Westfield San Francisco Shopping Centre; the Moscone Center and the San Francisco Museum of Modern ...

$229

$229
Parc 55 San Francisco - A Hilton Hotel
Parc 55 San Francisco - A Hilton Hotel
55 Cyril Magnin St, San Francisco
4.0 out of 5.0
4.0 out of 5 (526 reviews)

Just off Market Street, downtown San Francisco's major thoroughfare, this contemporary 32-story hotel is 1 block from San Francisco Centre shops and 3 blocks ...

$234

$234
Serrano Hotel
Serrano Hotel
405 Taylor St, San Francisco
4.0 out of 5.0
4.1 out of 5 (100 reviews)

The Serrano Hotel is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks from the Powell Street cable car.

$188

$188
Hotel Whitcomb
Hotel Whitcomb
1231 Market St, San Francisco
3.5 out of 5.0
3.4 out of 5 (455 reviews)

Located in the San Francisco theater district with a BART and MUNI station at its entrance, this downtown hotel is 6 blocks from Union Square and within a mile ...

$169

$169

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 48 hours. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.