$354 Cheap flight deals from St. Louis (STL) to Siena (FLR)

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This Weekend's Flight Deals from St. Louis to Siena

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 22 - Sat, May 30
STL
Lambert-St. Louis Intl.
FLR
Peretola
$1,672 Roundtrip, found 9 hours ago
$1,672
Roundtrip
found 9 hours ago
Select Lufthansa flight, departing Fri, May 22 from Lambert-St. Louis Intl. to Peretola, returning Sat, May 30, priced at $1,672 found 9 hours ago

Airfares from $354 One Way, $849 Round Trip from St. Louis to Siena

Prices starting at $849 for return flights and $354 for one-way flights to Siena were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Aug 16 - Sat, Aug 22
STL
St. Louis
FLR
Florence
$849 Roundtrip, found 3 days ago
$849
Roundtrip
found 3 days ago
Select Air Canada flight, departing Sun, Aug 16 from St. Louis to Florence, returning Sat, Aug 22, priced at $849 found 3 days ago
Sun, Aug 16 - Sat, Aug 22
STL
St. Louis
FLR
Florence
$914 Roundtrip, found 3 days ago
$914
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Sun, Aug 16 from St. Louis to Florence, returning Sat, Aug 22, priced at $914 found 3 days ago
Tue, Sep 8 - Tue, Sep 22
STL
St. Louis
FLR
Florence
$954 Roundtrip, found 4 days ago
$954
Roundtrip
found 4 days ago
Select Austrian Airlines flight, departing Tue, Sep 8 from St. Louis to Florence, returning Tue, Sep 22, priced at $954 found 4 days ago
Sun, Aug 16 - Sat, Aug 22
STL
St. Louis
FLR
Florence
$1,028 Roundtrip, found 3 days ago
$1,028
Roundtrip
found 3 days ago
Select Scandinavian Airlines flight, departing Sun, Aug 16 from St. Louis to Florence, returning Sat, Aug 22, priced at $1,028 found 3 days ago
Fri, Oct 2 - Sun, Oct 11
STL
St. Louis
FLR
Florence
$1,049 Roundtrip, found 2 days ago
$1,049
Roundtrip
found 2 days ago
Select Iberia flight, departing Fri, Oct 2 from St. Louis to Florence, returning Sun, Oct 11, priced at $1,049 found 2 days ago

Siena economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Social Hub Florence Belfiore
4.0-star property

The Social Hub Florence Belfiore

9.4/10 Exceptional! (518 reviews)

Jul 2 - Jul 5

3 night stay

St. Louis (STL) to Florence (FLR)

Lufthansa • Coach

Florence (FLR) to St. Louis (STL)

United • Coach
Price was $1,695, price is now $1,637 per person
$1,637
per person
found 1 day ago
Steps away from public transportation

Reviewed on Mar 30, 2026

Hotel Paris
3.0-star property

Hotel Paris

8.8/10 Excellent! (1,013 reviews)

Jul 2 - Jul 5

3 night stay

St. Louis (STL) to Florence (FLR)

Lufthansa • Coach

Florence (FLR) to St. Louis (STL)

United • Coach
Price was $1,955, price is now $1,723 per person
$1,723
per person
found 1 day ago
The charm of this hotel is that it was a palace built in the 1600's. As such it has some cosmetic defects that we actually enjoyed. The place is living history. Staff is great and the breakfast buffet was fresh and tasty. 24 hour espresso machine. A terrific location with everything in walking distance. Would stay again.

Reviewed on Nov 10, 2024

The Social Hub Florence Lavagnini
4.0-star property

The Social Hub Florence Lavagnini

9/10 Wonderful! (1,349 reviews)

Jul 2 - Jul 5

3 night stay

St. Louis (STL) to Florence (FLR)

Lufthansa • Coach

Florence (FLR) to St. Louis (STL)

United • Coach
Price was $1,741, price is now $1,647 per person
$1,647
per person
found 1 day ago
The hotel is located right next to a tram so it’s very easy to get there from the train station. It is about a 15 minute walk away from the Duomo and even further for the river and museums so that’s something to consider. I think this is one of the few hotels that has an elevator in it which is a huge plus when traveling with multiple bags. The views from the gym are absolutely gorgeous! There’s a laundry and kitchen in the basement and the lobby has one of those cute, retro photo booths that you can use. It even has swings in the entrance. The only complaint I had was they don’t allow irons in the room, you have to go all the way down to the basement to use the communal irons and ironing boards they have set up in the laundry. Otherwise, for the price and location? I’d recommend it.

Reviewed on Apr 10, 2026

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More About Flying To Siena from St. Louis

Route Information for Flights from St. Louis to Siena

Origin Airport IATA Code
STL
Destination Airport IATA Code
FLR
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Siena

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.