$329 Cheap flight deals from St. Louis (STL) to Cartagena (CTG)

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Airfares from $329 One Way, $621 Round Trip from St. Louis to Cartagena

Prices starting at $621 for return flights and $329 for one-way flights to Cartagena were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 17 - Tue, Apr 20
STL
St. Louis
CTG
Cartagena
$621 Roundtrip, found 3 days ago
$621
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Apr 17 from St. Louis to Cartagena, returning Tue, Apr 20, priced at $621 found 3 days ago
Tue, May 18 - Tue, May 25
STL
St. Louis
CTG
Cartagena
$628 Roundtrip, found 6 days ago
$628
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, May 18 from St. Louis to Cartagena, returning Tue, May 25, priced at $628 found 6 days ago
Sat, Apr 17 - Tue, Apr 20
STL
St. Louis
CTG
Cartagena
$634 Roundtrip, found 3 days ago
$634
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Apr 17 from St. Louis to Cartagena, returning Tue, Apr 20, priced at $634 found 3 days ago
Tue, May 18 - Tue, May 25
STL
St. Louis
CTG
Cartagena
$637 Roundtrip, found 6 days ago
$637
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, May 18 from St. Louis to Cartagena, returning Tue, May 25, priced at $637 found 6 days ago
Sat, Apr 17 - Tue, Apr 20
STL
St. Louis
CTG
Cartagena
$637 Roundtrip, found 3 days ago
$637
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Apr 17 from St. Louis to Cartagena, returning Tue, Apr 20, priced at $637 found 3 days ago

Cartagena economy flight packages

Price found within the past 48 hours. Click for updated prices.
Soy Local Islawa
3.0-star property

Soy Local Islawa

9/10 Wonderful! (40 reviews)

Oct 1 - Oct 5

4 night stay

St. Louis (STL) to Cartagena (CTG)

American Airlines • Non-stop roundtrip • Coach
Price was $1,474, price is now $1,011 per person
$1,011
per person
found 1 day ago
Peaceful stay with great views and friendly staff I really enjoyed my stay at this hotel in Isla Soy. The location is excellent, with nice views and a peaceful atmosphere that made it easy to relax. The hotel itself is great, and the staff were friendly and attentive throughout my visit — the service was one of the highlights. A couple of suggestions for improvement: it would be nice to have a few extra amenities or activities so the stay doesn’t feel limited if you’re there for several days. Breakfast was good, but a bit restricted in options. Also, they charge for almost any extra, including basic items like mayonnaise and ketchup, which felt a little excessive. Overall, I had a very pleasant experience and would definitely come back. The combination of the peaceful setting, nice views, and welcoming staff made the stay enjoyable.

Reviewed on Jul 31, 2026

ACASI Rustic Beach
3.0-star property

ACASI Rustic Beach

9.6/10 Exceptional! (11 reviews)

Oct 1 - Oct 4

3 night stay

St. Louis (STL) to Cartagena (CTG)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,803, price is now $1,037 per person
$1,037
per person
found 1 day ago

Makani Luxury Cartagena
4.0-star property

Makani Luxury Cartagena

9/10 Wonderful! (94 reviews)

Oct 1 - Oct 4

3 night stay

St. Louis (STL) to Cartagena (CTG)

American Airlines • Non-stop roundtrip • Coach
Price was $1,864, price is now $1,225 per person
$1,225
per person
found 1 day ago
Great exotic place.

Reviewed on Jul 28, 2026

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More About Flying To Cartagena from St. Louis

Route Information for Flights from St. Louis to Cartagena

Origin Airport IATA Code
STL
Destination Airport IATA Code
CTG
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Cartagena

Whether you want to book cheap flights from St. Louis to Cartagena or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for St. Louis to Cartagena flights.

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Frequently asked questions

What is the shortest flight from St. Louis to Cartagena?
Traveling from Lambert-St. Louis Intl. Airport (STL) to Cartagena Airport will take you at least 5 hours and 20 minutes. Savor a wine and watch a flick or two — it's the ideal opportunity to take some time out.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.