
$205 Cheap flight deals from Portland (PDX) to Santee (CAE)
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This Weekend's Flight Deals from Portland to Santee
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $205 One Way, $323 Round Trip from Portland to Santee
Prices starting at $323 for return flights and $205 for one-way flights to Santee were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santee economy flight packages

Sleep Inn Columbia
Nov 12 - Nov 13
Portland (PDX) to Columbia (CAE)
Reviewed on Sep 29, 2025

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Nov 12 - Nov 13
Portland (PDX) to Columbia (CAE)
Reviewed on Aug 7, 2025

Hilton Columbia Center
Nov 12 - Nov 13
Portland (PDX) to Columbia (CAE)
Reviewed on Oct 18, 2024
More About Flying To Santee from Portland
Route Information for Flights from Portland to Santee
Origin Airport IATA Code | PDX |
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Destination Airport IATA Code | CAE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Portland to Santee
Looking for cheap Portland to Santee flights? Orbitz has the cheapest air fares for flights from Portland to Santee. Plus, with our cutting-edge mobile tools, travel planning has never been easier or more wallet-friendly.
Mobile Deals and Steals
Orbitz is dedicated to providing low fares on Portland to Santee flights. Now you can find the latest deals on-the-go with Orbitz’s mobile apps for iPhone, iPad, Android phones, and tablets. Instantly see discounted rates for hotels, cruises, vacations, and air tickets for a great vacation.
Book Hotels With Confidence
When you’re looking for hotel rooms to go with your bargain flights from Portland to Santee, Orbitz provides you descriptions, photos, reviews, and location maps so you know exactly what you are booking. With easy-to-use Orbitz map tools, you can search for nearby hotels on your mobile device.
Access Your Flight Information Anytime
Use the Orbitz app or the mobile Orbitz site, m.orbtiz.com, to see information about your Portland to Santee flights anytime you need it. Your itinerary is also sent to your email address for reference. Access updates on your flights from Portland to Santee on your mobile device too, including delays and baggage claim details.
Cheap Air Ticket Prices Guaranteed
Orbitz is your number one source for low fares for Portland to Santee flights. Our low price guarantee on domestic and international air tickets give you great savings for a perfect trip to Santee. Need hotels too? You can book them last minute on your mobile phone.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.