$491 Cheap flight deals from Indianapolis (IND) to Palermo (PMO)

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Airfares from $491 One Way, $739 Round Trip from Indianapolis to Palermo

Prices starting at $739 for return flights and $491 for one-way flights to Palermo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Dec 4 - Sun, Dec 13
IND
Indianapolis
PMO
Palermo
$739 Roundtrip, found 1 day ago
$739
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Fri, Dec 4 from Indianapolis to Palermo, returning Sun, Dec 13, priced at $739 found 1 day ago
Wed, Mar 31 - Fri, Apr 9
IND
Indianapolis
PMO
Palermo
$1,197 Roundtrip, found 6 days ago
$1,197
Roundtrip
found 6 days ago
Select British Airways flight, departing Wed, Mar 31 from Indianapolis to Palermo, returning Fri, Apr 9, priced at $1,197 found 6 days ago
Fri, Oct 16 - Tue, Oct 20
IND
Indianapolis
PMO
Palermo
$1,313 Roundtrip, found 1 day ago
$1,313
Roundtrip
found 1 day ago
Select Swiss International Air Lines flight, departing Fri, Oct 16 from Indianapolis to Palermo, returning Tue, Oct 20, priced at $1,313 found 1 day ago
Fri, Dec 4 - Sun, Dec 13
IND
Indianapolis
PMO
Palermo
$1,315 Roundtrip, found 1 day ago
$1,315
Roundtrip
found 1 day ago
Select Turkish Airlines flight, departing Fri, Dec 4 from Indianapolis to Palermo, returning Sun, Dec 13, priced at $1,315 found 1 day ago
Fri, Dec 4 - Sun, Dec 13
IND
Indianapolis
PMO
Palermo
$1,349 Roundtrip, found 1 day ago
$1,349
Roundtrip
found 1 day ago
Select Brussels Airlines flight, departing Fri, Dec 4 from Indianapolis to Palermo, returning Sun, Dec 13, priced at $1,349 found 1 day ago

Palermo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Archè Design Rooms and Suites
3.0-star property

Archè Design Rooms and Suites

9.4/10 Exceptional! (61 reviews)

Nov 5 - Nov 11

6 night stay

Indianapolis (IND) to Palermo (PMO)

Delta • Coach

Palermo (PMO) to Indianapolis (IND)

KLM • Coach
Price was $1,525, price is now $1,361 per person
$1,361
per person
found 1 day ago
One of the best hotels we have stayed at. Great location, lovely products in the bathroom. Staff was available to provide recommendations and they arranged transfers for us. This is or new go to place when visiting palermo

Reviewed on Sep 15, 2026

Eurostars Centrale Palace
4.0-star property

Eurostars Centrale Palace

8.4/10 Very Good! (1,004 reviews)

Nov 5 - Nov 11

6 night stay

Indianapolis (IND) to Palermo (PMO)

Delta • Coach

Palermo (PMO) to Indianapolis (IND)

KLM • Coach
Price was $2,290, price is now $1,679 per person
$1,679
per person
found 1 day ago
A very nice hotel. Perfectly situated for attractions of the city and certainly for restaurants day and night. The building is actually a centuries old palace and many of the common rooms reflect this with nice decor and antique furnishings. A rooftop bar and restaurant compliment the high standards of the establishment. Service at reception, breakfast and staff in general was similarly always very good. Our standard room was a good size with a/c, fridge, TV, safe and tea and coffee facilities, very comfortable.Buffet breakfast was extensive, some hot choices, bacon, sausage, eggs, a considerable variety of cold meats, cheeses, yogurts and breads and cakes. Fresh fruit, tea, variety of coffees and cold juices completed and excellent start to the day.

Reviewed on Sep 30, 2026

Mercure Hotel Palermo Centro
4.0-star property

Mercure Hotel Palermo Centro

8.4/10 Very Good! (1,003 reviews)

Nov 5 - Nov 11

6 night stay

Indianapolis (IND) to Palermo (PMO)

Delta • Coach

Palermo (PMO) to Indianapolis (IND)

KLM • Coach
Price was $1,648, price is now $1,482 per person
$1,482
per person
found 1 day ago

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More About Flying To Palermo from Indianapolis

Route Information for Flights from Indianapolis to Palermo

Origin Airport IATA Code
IND
Destination Airport IATA Code
PMO
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Indianapolis to Palermo

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.