$109 Cheap flight deals from Cleveland (CLE) to Seneca (GSP)

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This Weekend's Flight Deals from Cleveland to Seneca

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 11 - Wed, Oct 15
CLE
Hopkins Intl.
GSP
Greenville-Spartanburg Intl.
$471 Roundtrip, found 4 days ago
$471
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Oct 11 from Hopkins Intl. to Greenville-Spartanburg Intl., returning Wed, Oct 15, priced at $471 found 4 days ago

Airfares from $109 One Way, $213 Round Trip from Cleveland to Seneca

Prices starting at $213 for return flights and $109 for one-way flights to Seneca were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Dec 2 - Wed, Dec 10
CLE
Cleveland
GSP
Greenville
$213 Roundtrip, found 4 days ago
$213
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Dec 2 from Cleveland to Greenville, returning Wed, Dec 10, priced at $213 found 4 days ago
Tue, Oct 28 - Wed, Oct 29
CLE
Cleveland
GSP
Greenville
$218 Roundtrip, found 6 days ago
$218
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 28 from Cleveland to Greenville, returning Wed, Oct 29, priced at $218 found 6 days ago
Tue, Dec 2 - Mon, Dec 8
CLE
Cleveland
GSP
Greenville
$227 Roundtrip, found 4 days ago
$227
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Dec 2 from Cleveland to Greenville, returning Mon, Dec 8, priced at $227 found 4 days ago
Thu, Dec 4 - Sun, Dec 7
CAK
Akron
GSP
Greenville
$229 Roundtrip, found 4 days ago
$229
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Dec 4 from Akron to Greenville, returning Sun, Dec 7, priced at $229 found 4 days ago
Tue, Oct 28 - Fri, Oct 31
CLE
Cleveland
GSP
Greenville
$229 Roundtrip, found 6 days ago
$229
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 28 from Cleveland to Greenville, returning Fri, Oct 31, priced at $229 found 6 days ago

Seneca economy flight packages

Price found within the past 48 hours. Click for updated prices.
Comfort Inn & Suites Greer - Greenville
2.5-star property

Comfort Inn & Suites Greer - Greenville

8.6/10 Excellent! (681 reviews)

Nov 14 - Nov 16

2 night stay

Cleveland (CLE) to Greenville (GSP)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $457, price is now $407 per person
$407
per person
found 6 hours ago
Extremely clean,quite and very affordable

Reviewed on Sep 2, 2025

Hotel Hartness
4.0-star property

Hotel Hartness

9.8/10 Exceptional! (587 reviews)

Nov 14 - Nov 16

2 night stay

Cleveland (CLE) to Greenville (GSP)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $665, price is now $520 per person
$520
per person
found 6 hours ago
First of all, LOVE the staff. We get drinks regularly at the hotel bar and the staff is amazing. We decided to stay in the hotel for a special occasion even though we have been loyal local customers since the restaurant and hotel opened. Overall, the experience was ok. The rooms are like a typical Hyatt or Hilton- nothing special. Our biggest issue was with breakfast. It was also ok, but sparse. Waiting for another batch of eggs to be cooked is understandable, but not having the pastries or cups restocked shows a lack of desire when the employee is standing there on her phone. And there must have been 7 employees standing around and snacking on the breakfast items around the time it closed, which is very bad optics. Our biggest issues was that the coffee was moved to the bar after breakfast but the creamer was spoiled. It appeared that it had not been refrigerated and was actually curdled; chunks came into our coffee cups. I think that Hotel Hartness needs to lean less on the architecture and surroundings and more on the little things that make a hotel experience something that is above average.

Reviewed on Mar 18, 2025

Hilton Greenville
3.5-star property

Hilton Greenville

8.2/10 Very Good! (1,015 reviews)

Nov 14 - Nov 16

2 night stay

Cleveland (CLE) to Greenville (GSP)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $494, price is now $426 per person
$426
per person
found 6 hours ago
This is our go-to hotel for all events at Clemson! Amazing hotel with the greatest staff!

Reviewed on Aug 22, 2025

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More About Flying To Seneca from Cleveland

Route Information for Flights from Cleveland to Seneca

Origin Airport IATA Code
CLE
Destination Airport IATA Code
GSP
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cleveland to Seneca

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.