$51 Cheap flight deals from Gainesville (MCO) to Biloxi (MOB)

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This Weekend's Flight Deals from Gainesville to Biloxi

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 26 - Mon, Sep 28
MCO
Orlando Intl.
MSY
Louis Armstrong New Orleans Intl.
$351 Roundtrip, found 4 hours ago
$351
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Sep 26 from Orlando Intl. to Louis Armstrong New Orleans Intl., returning Mon, Sep 28, priced at $351 found 4 hours ago
Sat, Sep 26 - Sun, Sep 27
JAX
Jacksonville Intl.
MSY
Louis Armstrong New Orleans Intl.
$782 Roundtrip, found 9 hours ago
$782
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Sep 26 from Jacksonville Intl. to Louis Armstrong New Orleans Intl., returning Sun, Sep 27, priced at $782 found 9 hours ago

Airfares from $51 One Way, $102 Round Trip from Gainesville to Biloxi

Prices starting at $102 for return flights and $51 for one-way flights to Biloxi were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Dec 3 - Sun, Dec 6
MCO
Orlando
GPT
Gulfport
$102 Roundtrip, found 6 days ago
$102
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Thu, Dec 3 from Orlando to Gulfport, returning Sun, Dec 6, priced at $102 found 6 days ago
Tue, Nov 3 - Tue, Nov 10
MCO
Orlando
MSY
New Orleans
$106 Roundtrip, found 6 days ago
$106
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Tue, Nov 3 from Orlando to New Orleans, returning Tue, Nov 10, priced at $106 found 6 days ago
Sun, Dec 13 - Wed, Dec 16
JAX
Jacksonville
MSY
New Orleans
$113 Roundtrip, found 2 days ago
$113
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Sun, Dec 13 from Jacksonville to New Orleans, returning Wed, Dec 16, priced at $113 found 2 days ago
Sat, Nov 14 - Tue, Nov 17
MCO
Orlando
MSY
New Orleans
$236 Roundtrip, found 1 day ago
$236
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Nov 14 from Orlando to New Orleans, returning Tue, Nov 17, priced at $236 found 1 day ago
Mon, Nov 16 - Sat, Nov 21
JAX
Jacksonville
GPT
Gulfport
$352 Roundtrip, found 1 day ago
$352
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 16 from Jacksonville to Gulfport, returning Sat, Nov 21, priced at $352 found 1 day ago

Biloxi economy flight packages

Price found within the past 48 hours. Click for updated prices.
Lamothe House
3.5-star property

Lamothe House

8.8/10 Excellent! (1,003 reviews)

Oct 29 - Nov 3

5 night stay

Orlando (MCO) to New Orleans (MSY)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $945, price is now $660 per person
$660
per person
found 19 hours ago
Hotel was amazing, parking was extra but safe and close (just behind the hotel). Pool and hot tub. One reason I chose this hotel was because it was August... in Louisiana... it is 1 million degrees (we live in north Louisiana so we already knew), so we NEEDED a swimming pool. I dove into the water after walking around all day and sweating out half my weight, and the water was 237 degrees. The maintenance man walked by while I was floating and I made a comment about it. He said he tried to turn it down but his boss wouldn't let him. PLEASE LET HIM!! Especially in the summer time.

Reviewed on Sep 19, 2026

Hotel Perle
4.5-star property

Hotel Perle

10/10 Exceptional! (58 reviews)

Oct 22 - Oct 25

3 night stay

Orlando (MCO) to New Orleans (MSY)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $2,147, price is now $1,433 per person
$1,433
per person
found 12 hours ago
Conveniently located, clean with covered parking, pool and bar, great rooms ample living room and bathrooms. All kitchen tools for cooking and a great bar for entertaining. Great choice

Reviewed on Aug 4, 2026

The Harlequin by AvantStay
3.5-star property

The Harlequin by AvantStay

9/10 Wonderful! (69 reviews)

Oct 25 - Oct 29

4 night stay

Orlando (MCO) to New Orleans (MSY)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $979, price is now $678 per person
$678
per person
found 1 day ago
Awesome stay, lication, assistance

Reviewed on Jul 28, 2026

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More About Flying To Biloxi from Gainesville

Route Information for Flights from Gainesville to Biloxi

Origin Airport IATA Code
MCO
Destination Airport IATA Code
MOB
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Gainesville to Biloxi

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Frequently asked questions

Are there non-stop flights from Gainesville to Biloxi?
Yep, your amazing getaway is just one simple flight away. Excellent news, isn't it? Cruise in comfort with one of the 3 carriers that fly direct from Orlando Intl. Airport to Louis Armstrong New Orleans Intl. Airport (MSY). Top options include:

  • Southwest Airlines
  • Spirit Airlines
  • Frontier Airlines

What is the shortest flight from Gainesville to Biloxi?
The trip from Gainesville to Biloxi can be as fast as 2 hours and 32 minutes. With a leisurely flight time like this, why not take off on an impulsive getaway?
What airlines fly from Gainesville to Biloxi most frequently?
The carriers that fly frequently between Orlando Intl. Airport and MSY include Southwest Airlines (WN). This popular option offers 95 flights on the route each month. Spirit Airlines (NK) will also get you to your destination in style and comfort. Offering 56 monthly flights between Gainesville and Biloxi, it's another popular airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.