$41 Cheap flight deals from Gainesville (MCO) to Biloxi (MOB)

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This Weekend's Flight Deals from Gainesville to Biloxi

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jun 8 - Sun, Jun 15
MCO
Orlando Intl.
GPT
Gulfport - Biloxi Intl.
$172 Roundtrip, found 3 days ago
$172
Roundtrip
found 3 days ago
Select Breeze Airways flight, departing Sun, Jun 8 from Orlando Intl. to Gulfport - Biloxi Intl., returning Sun, Jun 15, priced at $172 found 3 days ago
Sun, Jun 8 - Sun, Jun 15
MCO
Orlando Intl.
MSY
Louis Armstrong New Orleans Intl.
$220 Roundtrip, just found
$220
Roundtrip
just found
Select Spirit Airlines flight, departing Sun, Jun 8 from Orlando Intl. to Louis Armstrong New Orleans Intl., returning Sun, Jun 15, priced at $220 just found
Sat, Jun 7 - Wed, Jun 11
JAX
Jacksonville Intl.
MOB
Mobile Regional
$473 Roundtrip, found 2 days ago
$473
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Jun 7 from Jacksonville Intl. to Mobile Regional, returning Wed, Jun 11, priced at $473 found 2 days ago
Sun, Jun 8 - Fri, Jun 13
JAX
Jacksonville Intl.
MSY
Louis Armstrong New Orleans Intl.
$476 Roundtrip, found 4 hours ago
$476
Roundtrip
found 4 hours ago
Select United flight, departing Sun, Jun 8 from Jacksonville Intl. to Louis Armstrong New Orleans Intl., returning Fri, Jun 13, priced at $476 found 4 hours ago

Airfares from $41 One Way, $91 Round Trip from Gainesville to Biloxi

Prices starting at $91 for return flights and $41 for one-way flights to Biloxi were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 4 - Sun, Sep 7
MCO
Orlando
MSY
New Orleans
$91 Roundtrip, found 3 hours ago
$91
Roundtrip
found 3 hours ago
Select Spirit Airlines flight, departing Thu, Sep 4 from Orlando to New Orleans, returning Sun, Sep 7, priced at $91 found 3 hours ago
Sun, Jun 15 - Thu, Jun 26
MCO
Orlando
MSY
New Orleans
$92 Roundtrip, found 6 days ago
$92
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Sun, Jun 15 from Orlando to New Orleans, returning Thu, Jun 26, priced at $92 found 6 days ago
Sat, Aug 9 - Sun, Aug 17
MCO
Orlando
MSY
New Orleans
$100 Roundtrip, just found
$100
Roundtrip
just found
Select Spirit Airlines flight, departing Sat, Aug 9 from Orlando to New Orleans, returning Sun, Aug 17, priced at $100 just found
Thu, Oct 30 - Thu, Nov 6
MCO
Orlando
GPT
Gulfport
$102 Roundtrip, found 18 hours ago
$102
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Thu, Oct 30 from Orlando to Gulfport, returning Thu, Nov 6, priced at $102 found 18 hours ago
Thu, Nov 27 - Thu, Dec 4
JAX
Jacksonville
MSY
New Orleans
$117 Roundtrip, found 5 hours ago
$117
Roundtrip
found 5 hours ago
Select Breeze Airways flight, departing Thu, Nov 27 from Jacksonville to New Orleans, returning Thu, Dec 4, priced at $117 found 5 hours ago

Biloxi economy flight packages

Price found within the past 48 hours. Click for updated prices.
Catahoula Hotel
3.5-star property

Catahoula Hotel

7.8/10 Good! (999 reviews)

Jul 13 - Jul 16

3 night stay

Orlando (MCO) to New Orleans (MSY)

Breeze Airways • Coach

New Orleans (MSY) to Orlando (MCO)

Spirit Airlines • Coach
Save 100% on your flight
per person
found 20 hours ago
This was my second stay at the property. Pretty good price for Mardi Gras and decent location. The rooms are small but I was aware of that when booking . Room had a moldy smell and was so so clean. The shower in this room was tiny. Be aware the showers are in the room do not allow for any privacy if sharing a room.

Reviewed on Feb 13, 2024

International House Hotel
4.0-star property

International House Hotel

8.6/10 Excellent! (1,001 reviews)

Jul 4 - Jul 7

3 night stay

Orlando (MCO) to New Orleans (MSY)

Spirit Airlines • Roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
easy access to Borbour st, street car, taxi, restaurant. to a lot of the site seeing stops.

Reviewed on May 20, 2025

Embassy Suites by Hilton New Orleans
3.5-star property

Embassy Suites by Hilton New Orleans

7.8/10 Good! (1,665 reviews)

Jul 3 - Jul 6

3 night stay

Jacksonville (JAX) to New Orleans (MSY)

American Airlines • Non-stop • Coach

New Orleans (MSY) to Jacksonville (JAX)

Delta • Non-stop • Coach
per person
found 1 day ago
Full disclosure: After Hurricane Katrina in 2005, I spent six months living out of an Embassy Suites in Dallas. In the middle of so much uncertainty, that hotel gave me a sense of stability and comfort—and ever since, I’ve had a soft spot in my heart for Embassy Suites. So staying at the Embassy Suites by Hilton New Orleans during the Memorial Day weekend of 2025 felt like coming full circle, and I’m happy to say it did not disappoint. The location is perfect—just a short walk to the Convention Center and close to the Cruise Terminal, the WWII Museum, and all the energy of the French Quarter. The rooms were spacious and clean, and the staff was genuinely welcoming. The made-to-order breakfast each morning and the evening reception added a special touch that made the stay feel more personal than transactional. If you’re looking for a place that offers comfort, convenience, and a little bit of that “home away from home” feeling, this is it.

Reviewed on May 27, 2025

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Biloxi first class flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Le Marais
3.5-star property

Hotel Le Marais

8.6/10 Excellent! (1,007 reviews)

Jul 6 - Jul 10

4 night stay

Jacksonville (JAX) to New Orleans (MSY)

Delta • Non-stop roundtrip • FirstClass
per person
found 1 day ago
The location was great. It’s a half block away from Bourbon street. Close to be able to walk to almost everything we did. Staff was very friendly and accommodating. Room was nice. Only complaint was the bathroom was small. Not much space to put toiletries. Shower was narrow and no waste basket in bathroom. The shower pressure was amazing!! Pool is small but we did t use as it was chilly when we were there. Nice courtyard area for pool. Would definitely stay there again.

Reviewed on Feb 20, 2025

Virgin Hotels New Orleans
4.5-star property

Virgin Hotels New Orleans

9.4/10 Exceptional! (1,308 reviews)

Jul 6 - Jul 10

4 night stay

Jacksonville (JAX) to New Orleans (MSY)

Delta • Non-stop roundtrip • FirstClass
per person
found 1 day ago
The rooms are very odd. There is no bathroom. As soon as you walk in the door, you’re greeted by a sink nestled between two closets (two closets was nice however) and then you realize there is a glass door with a toilet behind it and one with a shower. The shower is in the foyer! The bedroom itself was a decent size. The bed was comfortable. The TV was ok. Not too many channels but just enough. The A/C was awful. Never got cool enough and not vents in the foyer where the nonexistent bathroom is. The room was also not as clean as I expected - the floors had hair all over them, the shower had rust, the grout was dirty, and the towels are not in great condition. Housekeeping however was kind and readily available when needed and so was maintenance. Actually all the staff was nice except no one answering the phone at night. This place is popular for party goers to visit and ironically we never ate, drank or partied here. I wouldn’t stay here again.

Reviewed on May 30, 2025

Hotel Perle
4.5-star property

Hotel Perle

10/10 Exceptional! (18 reviews)

Jul 6 - Jul 10

4 night stay

Jacksonville (JAX) to New Orleans (MSY)

Delta • Non-stop roundtrip • FirstClass
per person
found 1 day ago
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More About Flying To Biloxi from Gainesville

Route Information for Flights from Gainesville to Biloxi

Origin Airport IATA Code
MCO
Destination Airport IATA Code
MOB
Distance
550 mi
Direct Flight Airlines
Southwest Airlines, Spirit Airlines
Earliest Flight Arrival
11:02AM UTC
Latest Flight Arrival
2:50AM UTC

Gainesville to Biloxi

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Frequently asked questions

Are there non-stop flights from Gainesville to Biloxi?
Yep, your amazing getaway is just one simple flight away. Excellent news, isn’t it? Cruise in comfort with one of the 3 carriers that fly direct from Orlando Intl. Airport to Louis Armstrong New Orleans Intl. Airport (MSY). Top options include:

  • Southwest Airlines
  • Spirit Airlines
  • Frontier Airlines

What is the shortest flight from Gainesville to Biloxi?
The trip from Gainesville to Biloxi can be as fast as 2 hours and 32 minutes. With a leisurely flight time like this, why not take off on an impulsive getaway?
What airlines fly from Gainesville to Biloxi most frequently?
The carriers that fly frequently between Orlando Intl. Airport and MSY include Southwest Airlines (WN). This popular option offers 95 flights on the route each month. Spirit Airlines (NK) will also get you to your destination in style and comfort. Offering 56 monthly flights between Gainesville and Biloxi, it’s another popular airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.