$44 Cheap flight deals from Gainesville (MCO) to Biloxi (MOB)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Gainesville to Biloxi

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Mar 15 - Fri, Mar 20
MCO
Orlando Intl.
MSY
Louis Armstrong New Orleans Intl.
$245 Roundtrip, found 1 day ago
$245
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Mar 15 from Orlando Intl. to Louis Armstrong New Orleans Intl., returning Fri, Mar 20, priced at $245 found 1 day ago
Sun, Mar 15 - Tue, Mar 17
JAX
Jacksonville Intl.
MSY
Louis Armstrong New Orleans Intl.
$363 Roundtrip, found 5 days ago
$363
Roundtrip
found 5 days ago
Select Breeze Airways flight, departing Sun, Mar 15 from Jacksonville Intl. to Louis Armstrong New Orleans Intl., returning Tue, Mar 17, priced at $363 found 5 days ago
Sat, Mar 14 - Tue, Mar 24
MCO
Orlando Intl.
GPT
Gulfport - Biloxi Intl.
$459 Roundtrip, found 4 days ago
$459
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Mar 14 from Orlando Intl. to Gulfport - Biloxi Intl., returning Tue, Mar 24, priced at $459 found 4 days ago
Fri, Mar 13 - Sun, Mar 15
MCO
Orlando Intl.
MOB
Mobile Regional
$547 Roundtrip, found 3 days ago
$547
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Mar 13 from Orlando Intl. to Mobile Regional, returning Sun, Mar 15, priced at $547 found 3 days ago

Airfares from $44 One Way, $70 Round Trip from Gainesville to Biloxi

Prices starting at $70 for return flights and $44 for one-way flights to Biloxi were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Mar 26 - Fri, Mar 27
MCO
Orlando
MSY
New Orleans
$70 Roundtrip, found 4 days ago
$70
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Mar 26 from Orlando to New Orleans, returning Fri, Mar 27, priced at $70 found 4 days ago
Mon, Mar 9 - Fri, Mar 13
MCO
Orlando
MSY
New Orleans
$93 Roundtrip, found 2 days ago
$93
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Mon, Mar 9 from Orlando to New Orleans, returning Fri, Mar 13, priced at $93 found 2 days ago
Sun, May 24 - Sun, May 31
MCO
Orlando
GPT
Gulfport
$102 Roundtrip, found 3 hours ago
$102
Roundtrip
found 3 hours ago
Select Breeze Airways flight, departing Sun, May 24 from Orlando to Gulfport, returning Sun, May 31, priced at $102 found 3 hours ago
Sun, May 3 - Thu, May 7
JAX
Jacksonville
MSY
New Orleans
$143 Roundtrip, found 2 days ago
$143
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Sun, May 3 from Jacksonville to New Orleans, returning Thu, May 7, priced at $143 found 2 days ago
Tue, Jul 21 - Thu, Jul 30
MCO
Orlando
MSY
New Orleans
$219 Roundtrip, found 6 days ago
$219
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Tue, Jul 21 from Orlando to New Orleans, returning Thu, Jul 30, priced at $219 found 6 days ago

Biloxi economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bluegreen Club La Pension
3.0-star property

Bluegreen Club La Pension

9/10 Wonderful! (1,004 reviews)

Apr 9 - Apr 13

4 night stay

Orlando (MCO) to New Orleans (MSY)

Southwest Airlines • Coach

New Orleans (MSY) to Orlando (MCO)

Spirit Airlines • Coach
Price was $929, price is now $749 per person
$749
per person
found 1 day ago
Smack dab in the French quarter, convenient store next store. Dining to the left and right, clean room! Will come back

Reviewed on Oct 7, 2025

The Eleanor New Orleans
4.0-star property

The Eleanor New Orleans

9.4/10 Exceptional! (72 reviews)

Apr 16 - Apr 19

3 night stay

Orlando (MCO) to New Orleans (MSY)

Spirit Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $1,993, price is now $1,495 per person
$1,495
per person
found 1 day ago
Beautiful upgrade interior, very spacious, clean and smelled great. Great location but the parking garage for the property is dirty, tight and possibly unsafe. The communication was very automatic, mostly was through emails snd texts, not very personal. There are quite many rules and restrictions. Late check-in time And early check-out time created some inconvenience for our group. Significant charges for early checkin and late checkout. Besides these issues, we really enjoyed the place, a very great price for the suite. Will consider staying there again

Reviewed on Jan 18, 2025

The Louie Hotel New Orleans, Belvilla District 6 Formerly Sonder
4.0-star property

The Louie Hotel New Orleans, Belvilla District 6 Formerly Sonder

8/10 Very Good! (65 reviews)

Apr 22 - Apr 26

4 night stay

Orlando (MCO) to New Orleans (MSY)

Southwest Airlines • Roundtrip • Coach
Price was $1,702, price is now $1,308 per person
$1,308
per person
found 1 day ago
Great location, clean

Reviewed on Feb 16, 2025

Don't see what you're looking for?
See all available trips from Gainesville to Biloxi
View all trips

More About Flying To Biloxi from Gainesville

Route Information for Flights from Gainesville to Biloxi

Origin Airport IATA Code
MCO
Destination Airport IATA Code
MOB
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Gainesville to Biloxi

Looking for cheap Gainesville to Biloxi flights? Orbitz has the cheapest air fares for flights from Gainesville to Biloxi. Plus, with our cutting-edge mobile tools, travel planning has never been easier or more wallet-friendly.

Mobile Deals and Steals

Orbitz is dedicated to providing low fares on Gainesville to Biloxi flights. Now you can find the latest deals on-the-go with Orbitz’s mobile apps for iPhone, iPad, Android phones, and tablets. Instantly see discounted rates for hotels, cruises, vacations, and air tickets for a great vacation.

Book Hotels With Confidence

When you’re looking for hotel rooms to go with your bargain flights from Gainesville to Biloxi, Orbitz provides you descriptions, photos, reviews, and location maps so you know exactly what you are booking. With easy-to-use Orbitz map tools, you can search for nearby hotels on your mobile device.

Access Your Flight Information Anytime

Use the Orbitz app or the mobile Orbitz site, m.orbtiz.com, to see information about your Gainesville to Biloxi flights anytime you need it. Your itinerary is also sent to your email address for reference. Access updates on your flights from Gainesville to Biloxi on your mobile device too, including delays and baggage claim details.

Cheap Air Ticket Prices Guaranteed

Orbitz is your number one source for low fares for Gainesville to Biloxi flights. Our low price guarantee on domestic and international air tickets give you great savings for a perfect trip to Biloxi. Need hotels too? You can book them last minute on your mobile phone.

Frequently asked questions

Are there non-stop flights from Gainesville to Biloxi?
Yep, your amazing getaway is just one simple flight away. Excellent news, isn't it? Cruise in comfort with one of the 3 carriers that fly direct from Orlando Intl. Airport to Louis Armstrong New Orleans Intl. Airport (MSY). Top options include:

  • Southwest Airlines
  • Spirit Airlines
  • Frontier Airlines

What is the shortest flight from Gainesville to Biloxi?
The trip from Gainesville to Biloxi can be as fast as 2 hours and 32 minutes. With a leisurely flight time like this, why not take off on an impulsive getaway?
What airlines fly from Gainesville to Biloxi most frequently?
The carriers that fly frequently between Orlando Intl. Airport and MSY include Southwest Airlines (WN). This popular option offers 95 flights on the route each month. Spirit Airlines (NK) will also get you to your destination in style and comfort. Offering 56 monthly flights between Gainesville and Biloxi, it's another popular airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.