
$59 Cheap flight deals from Knoxville (TYS) to Littleton (DEN)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Knoxville to Littleton
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $59 One Way, $112 Round Trip from Knoxville to Littleton
Prices starting at $112 for return flights and $59 for one-way flights to Littleton were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Littleton economy flight packages

Spark by Hilton Denver International Airport
Dec 11 - Dec 15
Knoxville (TYS) to Denver (DEN)
Reviewed on Oct 14, 2025

The Westin Denver International Airport
Dec 11 - Dec 15
Knoxville (TYS) to Denver (DEN)
Reviewed on Jul 14, 2025

Hyatt Vacation Club at The Ranahan
Dec 18 - Dec 21
Knoxville (TYS) to Denver (DEN)
Reviewed on Sep 20, 2025
Littleton first class flight packages

Hyatt Vacation Club at The Ranahan
Nov 30 - Dec 4
Knoxville (TYS) to Denver (DEN)
Denver (DEN) to Knoxville (TYS)
Reviewed on Sep 20, 2025

Lodge at Vail Condominiums
Nov 30 - Dec 4
Knoxville (TYS) to Denver (DEN)
Denver (DEN) to Knoxville (TYS)

Hotel Alpenrock Breckenridge, Curio Collection by Hilton
Nov 30 - Dec 4
Knoxville (TYS) to Denver (DEN)
Denver (DEN) to Knoxville (TYS)
Reviewed on Oct 11, 2025
More About Flying To Littleton from Knoxville
Route Information for Flights from Knoxville to Littleton
| Origin Airport IATA Code | TYS | 
|---|---|
| Destination Airport IATA Code | DEN | 
| Distance | |
| Direct Flight Airlines | |
| Earliest Flight Arrival | |
| Latest Flight Arrival | 
Knoxville to Littleton
Getting a spectacularly low fare on Knoxville to Littleton flights is always possible when you use Orbitz as your personal travel planner. Orbitz is your essential travel resource for low cost flights from Knoxville to Littleton, discount hotel accommodations, cheap car rentals, and more.
Research and Book Knoxville to Littleton Flights on the Go
Our free cutting-edge mobile apps for iPad, Android, and iPhone make it easy to find the best fares when researching and booking flights from Knoxville to Littleton. You can also use the apps to check your flight status, find baggage claims details, and get exclusive mobile discount rates on car rentals and hotels.
Earn Miles and Points for Your Frequent Flyer Program
Build up points or miles for your frequent flyer plan with qualifying Knoxville to Littleton flights. Simply add your frequent flyer number when booking your domestic or international flights or enter the numbers in your Orbitz account profile to automatically add them to your bookings.
Flight Alerts Take the Hassle out of Travel
You can get email, SMS text, or voicemail updates regarding any major changes to your flights from Knoxville to Littleton. These free alerts can also be sent to as many as six additional contacts, ensuring that your friends, colleagues, or family are aware of changes to your arrival time.
Stay in Your Budget and Still Get Great Accommodations
Orbitz shoppers can access affordable vacation packages and have the option of booking their departure and arrival flights through different airlines, making travel less costly and more convenient. The best prices on flights from Knoxville to Littletonare always found on Orbitz.
Flights from Knoxville
- Knoxville to Orlando
- Knoxville to New York
- Knoxville to Dallas
- Knoxville to Chicago
- Knoxville to Houston
- Knoxville to Los Angeles
- Knoxville to Washington
- Knoxville to Detroit
- Knoxville to New Orleans
- Knoxville to Toronto
- Knoxville to London
- Knoxville to Kansas City
- Knoxville to Sacramento
- Knoxville to San Francisco
- Knoxville to Hartford
- Knoxville to Rome
- Knoxville to Anchorage
- Knoxville to Paris
- Knoxville to Killeen
- Knoxville to Beijing
Knoxville Airports
More Destinations
- Flights from Baltimore to Southeast Denver
- Flights from Charlotte to Southeast Denver
- Flights from New York to Southeast Denver
- Flights from Phoenix to Southeast Denver
- Flights from Seattle to Southeast Denver
- Flights from Chicago to Southwest
- Flights from Dallas to Southwest
- Flights from Detroit to Southwest
- Flights from Houston to Southwest
- Flights from Miami to Southwest
- Flights from Minneapolis - St. Paul to Southwest
- Flights from New York to Southwest
- Flights from Orlando to Southwest
- Flights from Phoenix to Southwest
- Flights from Salt Lake City to Southwest
- Flights from Washington to Southwest
- Flights from Atlanta to Englewood
- Flights from Boston to Englewood
- Flights from Chicago to Englewood
- Flights from Dallas to Englewood
- Flights from Detroit to Englewood
- Flights from Houston to Englewood
- Flights from London to Englewood
- Flights from Los Angeles to Englewood
- Flights from Miami to Englewood
- Flights from Minneapolis - St. Paul to Englewood
- Flights from New York to Englewood
- Flights from Orlando to Englewood
- Flights from Phoenix to Englewood
- Flights from Seattle to Englewood
- Flights from Washington to Englewood
- Flights from Durango to Englewood
- Flights from Sacramento to Englewood
- Flights from Fort Lauderdale to Englewood
- Flights from Newark to Englewood
- Flights from Burlington to Englewood
- Flights from Syracuse to Englewood
- Flights from Fort Myers to Englewood
- Flights from Grand Rapids to Englewood
- Flights from Shenzhen to Englewood
- Flights from El Paso to Denver
- Flights from Grand Junction to Denver
- Flights from Atlanta to Denver
- Flights from Austin to Denver
- Flights from Boston to Denver
- Flights from Charlotte to Denver
- Flights from Chicago to Denver
- Flights from Columbus to Denver
- Flights from Dallas to Denver
- Flights from Detroit to Denver
- Flights from Houston to Denver
- Flights from Indianapolis to Denver
- Flights from Kansas City to Denver
- Flights from Las Vegas to Denver
- Flights from Los Angeles to Denver
- Flights from Memphis to Denver
- Flights from Miami to Denver
- Flights from Minneapolis - St. Paul to Denver
- Flights from New Orleans to Denver
- Flights from New York to Denver
- Flights from Orlando to Denver
- Flights from Philadelphia to Denver
- Flights from Phoenix to Denver
- Flights from Salt Lake City to Denver
- Flights from San Antonio to Denver
- Flights from Seattle to Denver
- Flights from Toronto to Denver
- Flights from Charleston to Denver
- Flights from Santa Fe to Denver
- Flights from Durango to Denver
- Flights from Sacramento to Denver
- Flights from Des Moines to Denver
- Flights from Pittsburgh to Denver
- Flights from Richmond to Denver
- Flights from Syracuse to Denver
- Flights from Tulsa to Denver
- Flights from Bentonville - Fayetteville to Denver
- Flights from Milwaukee to Denver
- Flights from Albuquerque to Denver
- Flights from Buffalo to Denver
- Flights from Reno to Denver
- Flights from Madison to Denver
- Flights from Little Rock to Denver
- Flights from Spokane to Denver
- Flights from Springfield to Denver
- Flights from Oklahoma City to Denver
- Flights from Knoxville to Denver
- Flights from Provo to Denver
- Flights from Cedar Rapids - Iowa City to Denver
- Flights from Tucson to Denver
- Flights from Colorado Springs to Denver
- Flights from Tampa to Denver
- Flights from Jacksonville to Denver
- Flights from Boise to Denver
- Flights from Louisville to Denver
- Flights from Grand Rapids to Denver
- Flights from Wichita to Denver
- Flights from Fargo to Denver
- Flights from Sioux Falls to Denver
- Flights from Burbank to Denver
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
