$87 Cheap flight deals from San Francisco (SJC) to Southern Indiana (SDF)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from San Francisco to Southern Indiana

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Aug 17 - Tue, Aug 26
SFO
San Francisco Intl.
CVG
Cincinnati - Northern Kentucky Intl.
$329 Roundtrip, found 3 hours ago
$329
Roundtrip
found 3 hours ago
Select Breeze Airways flight, departing Sun, Aug 17 from San Francisco Intl. to Cincinnati - Northern Kentucky Intl., returning Tue, Aug 26, priced at $329 found 3 hours ago
Sun, Aug 17 - Wed, Aug 20
SFO
San Francisco Intl.
SDF
Louisville Intl.
$426 Roundtrip, found 3 days ago
$426
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, Aug 17 from San Francisco Intl. to Louisville Intl., returning Wed, Aug 20, priced at $426 found 3 days ago
Sun, Aug 17 - Mon, Aug 25
SJC
Norman Y. Mineta San Jose Intl.
CVG
Cincinnati - Northern Kentucky Intl.
$438 Roundtrip, found 2 days ago
$438
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Aug 17 from Norman Y. Mineta San Jose Intl. to Cincinnati - Northern Kentucky Intl., returning Mon, Aug 25, priced at $438 found 2 days ago
Sat, Aug 16 - Tue, Aug 26
OAK
Oakland Intl.
CVG
Cincinnati - Northern Kentucky Intl.
$543 Roundtrip, found 1 day ago
$543
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sat, Aug 16 from Oakland Intl. to Cincinnati - Northern Kentucky Intl., returning Tue, Aug 26, priced at $543 found 1 day ago

Airfares from $87 One Way, $175 Round Trip from San Francisco to Southern Indiana

Prices starting at $175 for return flights and $87 for one-way flights to Southern Indiana were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 11 - Mon, Sep 15
OAK
Oakland
SDF
Louisville
$175 Roundtrip, found 5 days ago
$175
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Thu, Sep 11 from Oakland to Louisville, returning Mon, Sep 15, priced at $175 found 5 days ago
Fri, Sep 5 - Mon, Sep 8
SFO
San Francisco
SDF
Louisville
$186 Roundtrip, just found
$186
Roundtrip
just found
Select Breeze Airways flight, departing Fri, Sep 5 from San Francisco to Louisville, returning Mon, Sep 8, priced at $186 just found
Thu, Sep 11 - Fri, Sep 19
SJC
San Jose
SDF
Louisville
$188 Roundtrip, found 2 days ago
$188
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Thu, Sep 11 from San Jose to Louisville, returning Fri, Sep 19, priced at $188 found 2 days ago
Tue, Aug 26 - Tue, Sep 16
SFO
San Francisco
CVG
Cincinnati
$200 Roundtrip, found 6 days ago
$200
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Tue, Aug 26 from San Francisco to Cincinnati, returning Tue, Sep 16, priced at $200 found 6 days ago
Tue, Jan 6 - Tue, Jan 13
SFO
San Francisco
CVG
Cincinnati
$210 Roundtrip, found 3 days ago
$210
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Tue, Jan 6 from San Francisco to Cincinnati, returning Tue, Jan 13, priced at $210 found 3 days ago

Southern Indiana economy flight packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express Hotel & Suites Harrison by IHG
2.5-star property

Holiday Inn Express Hotel & Suites Harrison by IHG

8.2/10 Very Good! (493 reviews)

Oct 2 - Oct 6

4 night stay

San Francisco (SFO) to Cincinnati (CVG)

Frontier Airlines • Non-stop roundtrip • Coach
per person
found 16 hours ago
Clean hotel. Area nearby is on the rough side. Elevator was out.

Reviewed on Mar 6, 2022

Embassy Suites by Hilton Cincinnati Northeast Blue Ash
3.5-star property

Embassy Suites by Hilton Cincinnati Northeast Blue Ash

8/10 Very Good! (1,004 reviews)

Oct 2 - Oct 6

4 night stay

San Francisco (SFO) to Cincinnati (CVG)

Frontier Airlines • Non-stop roundtrip • Coach
per person
found 16 hours ago
I had stayed here 20 years ago and it was very nice. It now is getting very rundown. It’s a shame because it has potential

Reviewed on Jun 30, 2025

The Lytle Park Hotel, Autograph Collection
4.5-star property

The Lytle Park Hotel, Autograph Collection

9.6/10 Exceptional! (242 reviews)

Oct 2 - Oct 6

4 night stay

San Francisco (SFO) to Cincinnati (CVG)

Frontier Airlines • Non-stop roundtrip • Coach
per person
found 16 hours ago
We love this property. Amazing customer service but unfortunately we booked the room with a large tub and found out it was not available when we arrived. They did comp us breakfast for the inconvenience but the main reason I booked this hotel was for this specific room for our honeymoon. We did have another mishap where the valet accidently grabbed our other vehicles key (that’s was parked at home) from our cup holder and when we got home 2hrs away we realized it was gone. Unfortunately we had to have them ship the key to us which took a few days, had to pay for a pop-a-lock to unlock the vehicle for us to get valuables, and had to get a rental car since we were down a vehicle. Just unfortunate mishaps on this experience but the facility was beautiful.

Reviewed on Jan 2, 2025

Don't see what you're looking for?
See all available trips from San Francisco to Southern Indiana
View all trips

More About Flying To Southern Indiana from San Francisco

Route Information for Flights from San Francisco to Southern Indiana

Origin Airport IATA Code
SJC
Destination Airport IATA Code
SDF
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

San Francisco to Southern Indiana

Book your trip through Orbitz for the best deals on San Francisco to Southern Indiana flights. With our cutting-edge mobile tools, getting fantastic savings on international or domestic flights or updates on your flight status has never been easier. Find your low-priced flights from San Francisco to Southern Indiana today with Orbitz.

Frequent Flyer Rewards

If you are a member of a frequent flyer program, Orbitz will ensure you get points or miles for your qualifying San Francisco to Southern Indiana flights. Just provide your frequent flyer number or your loyalty program number when booking your flight online with Orbtiz.com.

Flight Deals on the Go

Never miss out on great savings! Get fantastic deals on flights from San Francisco to Southern Indiana on your mobile device with our apps for iPhone, Android, and iPad, or use your mobile Web browser to access m.orbitz.com. Find big discounts on the hotels you want to stay at to go along with your San Francisco to Southern Indiana flights. The app even gives you information for baggage claim and other important flight details.

Free Flight Alerts

With Orbitz, not do you get amazing low-cost deals on San Francisco to Southern Indiana flights, but we can send you flight alerts to your mobile phone or email. Instantly learn about delays to your flights from San Francisco to Southern Indiana, so you can plan ahead and make different travel arrangements if you need to.

Guaranteed low prices for San Francisco to Southern Indiana flights makes Orbitz the perfect online budget travel source.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.