Hotels in Sikeston

Search over 289 hotels from $67

Start date: Check-in selected.
To Date
End date: Check-out

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Feb 8 - Feb 9
Tonight
Check prices in Sikeston for tonight, Feb 8 - Feb 9
Feb 9 - Feb 10
Tomorrow night
Check prices in Sikeston for tomorrow night, Feb 9 - Feb 10

Top Rated Sikeston Hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.13 mi from city center
$90 nightly
The price is $103 total per night
$103 total
Feb 15 - Feb 16
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.46 mi from city center
$96 nightly
The price is $109 total per night
$109 total
Feb 28 - Mar 1
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.35 mi from city center
$85 nightly
The price is $97 total per night
$97 total
Feb 22 - Feb 23
Total with taxes and fees
Guests of Best Western Plus Sikeston I-55 have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.07 mi from city center
$58 nightly
The price is $67 total per night
$67 total
Feb 9 - Feb 10
Total with taxes and fees
Guests of Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.
Breakfast included
Pet friendly
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.34 mi from city center
$68 nightly
The price is $78 total per night
$78 total
Feb 11 - Feb 12
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Breakfast included
Pet friendly
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
Free Cancellation
Reserve now, pay when you stay
2.87 mi from city center
$59 nightly
The price is $68 total per night
$68 total
Feb 9 - Feb 10
Total with taxes and fees
Guests staying at Super 8 by Wyndham Sikeston/Miner Area enjoy free WiFi in public areas, a library, and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Breakfast included
Pet friendly
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 out of 5
1239 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.56 mi from city center
$101 nightly
The price is $114 total per night
$114 total
Feb 19 - Feb 20
Total with taxes and fees
Guests of Fairfield Inn & Suites by Marriott Sikeston enjoy an indoor pool, free WiFi in public areas, and coffee in a common area. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. This hotel also has laundry facilities.
Pool
Breakfast included
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue Sikeston MO
3.06 mi from city center
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and a business center.
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Free Cancellation
1.41 mi from city center
$110 nightly
The price is $125 total per night
$125 total
Feb 15 - Feb 16
Total with taxes and fees
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.54 mi from city center
$144 nightly
The price is $163 total per night
$163 total
Feb 12 - Feb 13
Total with taxes and fees
At TownePlace Suites by Marriott Sikeston, guests have access to an indoor pool, free WiFi in public areas, and coffee in a common area. Free parking is included with your stay. The 24-hour front desk has multilingual staff ready to assist with securing valuables and concierge services. Additional amenities include a computer station, laundry facilities, and local meal delivery service.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
29.57 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Feb 12 - Feb 13
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
30.33 mi from city center
$96 nightly
The price is $109 total per night
$109 total
Feb 9 - Feb 10
Total with taxes and fees
Guests of The Riverview enjoy features like a casino, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a conference center, a microwave in a common area, and a vending machine.
Don't see what you're looking for?
See all available properties in Sikeston
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Sikeston hotels options

    Pear Tree Inn Sikeston

    Pear Tree Inn Sikeston

    2602 E Malone Avenue Sikeston MO
    9.2/10 Wonderful! (1,002 reviews)
    Pear Tree Inn Cape Girardeau West

    Pear Tree Inn Cape Girardeau West

    103 Cape West Pkwy Cape Girardeau MO
    $72 nightly
    The price is $81 total per night from Feb 12 to Feb 13
    $81 total
    Feb 12 - Feb 13
    Total with taxes and fees
    9/10 Wonderful! (1,001 reviews)
    Days Inn and Suites by Wyndham Sikeston

    Days Inn and Suites by Wyndham Sikeston

    220 S Interstate Dr Sikeston MO
    $68 nightly
    The price is $78 total per night from Feb 11 to Feb 12
    $78 total
    Feb 11 - Feb 12
    Total with taxes and fees
    7.2/10 Good! (1,000 reviews)
    Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

    Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

    3253 William Street Cape Girardeau MO
    $99 nightly
    The price is $112 total per night from Mar 1 to Mar 2
    $112 total
    Mar 1 - Mar 2
    Total with taxes and fees
    9.4/10 Exceptional! (1,004 reviews)
    Eagle Inn Charleston

    Eagle Inn Charleston

    2811 East Marshall Street Charleston MO
    $64 nightly
    The price is $71 total per night from Feb 9 to Feb 10
    $71 total
    Feb 9 - Feb 10
    Total with taxes and fees
    6.6/10 (105 reviews)
    Super 8 by Wyndham Charleston/Sikeston East MO

    Super 8 by Wyndham Charleston/Sikeston East MO

    310 S Story St Charleston MO
    $62 nightly
    The price is $69 total per night from Feb 9 to Feb 10
    $69 total
    Feb 9 - Feb 10
    Total with taxes and fees
    6.6/10 (621 reviews)

Where is a good place to stay in Sikeston?

What are the best hotels to stay with the kids in Sikeston?

Check out these hotels for you and the kids in Sikeston. Drury Inn & Suites Sikeston, MO is a hotel offering an outdoor pool, free parking, and free breakfast. You and your family can also consider Pear Tree Inn Sikeston, a hotel offering an outdoor pool, free breakfast, and laundry facilities.

What are some of the best hotels in central Sikeston?

These are some of our travelers' favorite hotels in central Sikeston:

You'll love Sikeston for its array of shops and popular restaurants.

What are some favorite hotels close to Isle Casino Cape Girardeau?

Try your luck at this well-known casino, 3.6 mi from central Cape Girardeau. You'll find 9 hotels within a mile of Isle Casino Cape Girardeau and here are some of the top choices in the area:

Sikeston hotels essential information

Accommodation
289 hotels
Lowest Price
$67
Highest Price
$163
Popular hotels
Drury Inn & Suites Sikeston, MO, Hampton Inn Sikeston, Best Western Plus Sikeston, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67), Days Inn and Suites by Wyndham Sikeston, Super 8 by Wyndham Sikeston/Miner Area, Fairfield Inn & Suites by Marriott Sikeston, Pear Tree Inn Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG, TownePlace Suites by Marriott Sikeston, Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview

Recent Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

5/5 Excellent
"Yes ever thing was great"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Posted 5 hours ago
Drury Inn & Suites Sikeston, MO

More to Explore