Book 5 Star Hotels in Florida Keys
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Florida Keys 5 Stars Hotels
Hawks Cay Resort
61 Hawks Cay Blvd, Marathon, FL
Free Cancellation
Reserve now, pay when you stay
16.01 mi from city center
$361 nightly
The price is $405 total per night
$405 total
Aug 22 - Aug 23
Total includes taxes and fees
Hawks Cay Resort features a private beach, a marina, and a full-service spa. Parking is available for USD 28.13 per day (USD 50.63 per day for valet parking), and there's also limo/town car service. The 24-hour front desk has multilingual staff ready to assist with securing valuables and concierge services. Other amenities at this beach hotel include 5 outdoor pools, a children's pool, and a gym.
On private beach
Pool
Isla Bella Beach Resort & Spa
1 Knights Key Boulevard, MM 47, Marathon, FL
Free Cancellation
Reserve now, pay when you stay
6.94 mi from city center
$317 nightly
The price is $357 total per night
$357 total
Aug 28 - Aug 29
Total includes taxes and fees
Guests of Isla Bella Beach Resort & Spa have access to a full-service spa, 5 outdoor pools, and a gym. Valet parking is offered for USD 50 per day. Front-desk staff can answer questions 24/7, and assist with tours or tickets, luggage storage, and securing valuables. Other amenities at this beach hotel include a steam room, free WiFi in public areas, and meeting rooms.
Pool
Spa
Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
Free Cancellation
Reserve now, pay when you stay
34.15 mi from city center
$259 nightly
The price is $291 total per night
$291 total
Jul 31 - Aug 1
Total includes taxes and fees
Cheeca Lodge & Spa features a private beach, a golf course, and a full-service spa. Free valet and self parking are available, and there's also limo/town car service. The front desk has multilingual staff on hand 24/7 to help with tours or tickets, luggage storage, and securing valuables. Other amenities at this beach resort include 3 outdoor pools, a 24-hour gym, and a sauna.
On private beach
Pool
Chesapeake Beach Resort
83409 Overseas Hwy, Islamorada, FL
Free Cancellation
Reserve now, pay when you stay
35.77 mi from city center
$201 nightly
The price is $226 total per night
$226 total
Aug 12 - Aug 13
Total includes taxes and fees
Chesapeake Beach Resort features a private beach, a marina, and 2 outdoor pools. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Other amenities at this beach hotel include free WiFi in public areas, coffee/tea in a common area, and free use of bicycles.
On private beach
Pool
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy, Key Largo, FL
47.1 mi from city center
$364 nightly
The price is $409 total per night
$409 total
Aug 12 - Aug 13
Total includes taxes and fees
Guests of Baker's Cay Resort Key Largo, Curio Collection by Hilton have access to a private beach, 2 outdoor pools, and a gym. Parking is available for USD 11.20 per night (USD 16.80 per night for valet parking), and there's also limo/town car service. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this beach resort include a hot tub, a conference center, and a 24-hour business center.
On private beach
Pool
Hampton Inn Key Largo Manatee Bay
102400 Overseas Hwy, Key Largo, FL
Free Cancellation
Reserve now, pay when you stay
51.86 mi from city center
$118 nightly
The price is $133 total per night
$133 total
Aug 17 - Aug 18
Total includes taxes and fees
At Hampton Inn Key Largo Manatee Bay, guests enjoy a private beach, an outdoor pool, and a gym. A stay here includes free parking. The 24-hour front desk has multilingual staff ready to assist with luggage storage, concierge services, and securing valuables. Other amenities at this beach hotel include free WiFi in public areas, a 24-hour business center, and coffee/tea in a common area.
On private beach
Pool
Islander Resort
82100 Overseas Highway, Islamorada, FL
Free Cancellation
Reserve now, pay when you stay
34.56 mi from city center
$268 nightly
The price is $302 total per night
$302 total
Aug 11 - Aug 12
Total includes taxes and fees
Guests of Islander Resort have access to a private beach, 2 outdoor pools, and a gym. Free parking is available if you drive. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, concierge services, and luggage storage. Other amenities at this beach hotel include free WiFi in public areas, meeting rooms, and a conference center.
On private beach
Pool
Amara Cay Resort
80001 Overseas Hwy, Islamorada, FL
Free Cancellation
Reserve now, pay when you stay
32.61 mi from city center
$253 nightly
The price is $285 total per night
$285 total
Aug 10 - Aug 11
Total includes taxes and fees
At Amara Cay Resort, guests enjoy a private beach, an outdoor pool, and a gym. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this beach resort include a meeting room, a terrace, and laundry facilities.
On private beach
Pool
Holiday Inn Key Largo by IHG
99701 Overseas Hwy, Key Largo, FL
Free Cancellation
49.83 mi from city center
$148 nightly
The price is $167 total per night
$167 total
Aug 14 - Aug 15
Total includes taxes and fees
Guests of Holiday Inn Key Largo by IHG have access to a marina, 2 outdoor pools, and a 24-hour gym. If you decide to drive, there's free parking. The 24-hour front desk has multilingual staff ready to assist with securing valuables, luggage storage, and concierge services. Other amenities at this beach hotel include free WiFi in public areas, a hot tub, and conference space.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best 5 star hotels in Florida Keys
Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Florida Keys. After all, treating yourself to the finer things is what vacations are about.
What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Florida Keys hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.
What amenities can I expect at a 5 star hotel?
Florida Keys 5 star hotels and resorts typically offer luxury amenities such as:
- Gourmet restaurant
- Full-service fitness center with pool
- Luxury spa
- Welcome gifts upon arrival
- Top-of-the-line beds and linens
- Designer personal care products
- Premium cable, free Wi-Fi and device docking stations
How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Florida Keys with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place:
- Search hotels by price, ranging from $133 to $409
- Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
- Choose from 8,239 5 star hotels in Florida Keys!
Florida Keys hotels essential information
Accommodation | 8,239 hotels |
|---|---|
Lowest Price | $133 |
Highest Price | $409 |
Popular hotels | Hawks Cay Resort, Isla Bella Beach Resort & Spa, Cheeca Lodge & Spa, Chesapeake Beach Resort, Baker's Cay Resort Key Largo, Curio Collection by Hilton, Hampton Inn Key Largo Manatee Bay, Islander Resort, Amara Cay Resort, Holiday Inn Key Largo by IHG |
Recent Reviews
Isla Bella Beach Resort & Spa
5/5 Excellent
"The only thing we didn’t like is that there is no music around the resort. "
A verified traveler stayed at Isla Bella Beach Resort & Spa
Posted 1 day ago
Areas Of Florida Keys
Hotels Near
Hotel Themes
Flights To
Top Trending
Hotels
- Pocono Mountains All Inclusive Resorts & Hotels
- Pocono Mountains Romantic Getaways & Hotels
- Pocono Mountains Hotels with Hot Tubs
- Southern Indiana Waterpark Hotels & Resorts
- Northern California Hotels with Hot Tubs
- Gulf Coast Kid Friendly Hotels
- Gulf Coast Waterpark Hotels & Resorts
- Pocono Mountains Spa Resorts & Hotels
- Southern California Hotels with a Lazy River
- Western Maryland Spa Resorts & Hotels
- Northern California Casino Resorts & Hotels
- Southeastern United States All Inclusive Resorts & Hotels
- Western United States All Inclusive Resorts & Hotels
- Southern California Hotels with Waterslides
- Pocono Mountains Kid Friendly Hotels
- Southern California Romantic Getaways & Hotels
- Southern California Spa Resorts & Hotels
- Northern California Kid Friendly Hotels
- Pocono Mountains Hotel Deals
- Pocono Mountains Waterpark Hotels & Resorts
- Northern California All Inclusive Resorts & Hotels
- Ozarks Kid Friendly Hotels
- Northern California Beach Resorts & Hotels
- Southern California Hotels with Hot Tubs
- Gulf Coast Beach Resorts & Hotels
- Northern California Spa Resorts & Hotels
- Southern California Hotels with an Indoor Pool
- Pocono Mountains Hotels with an Indoor Pool
- Quad Cities Hotels with Hot Tubs