Top St. Louis Union Station vacation deals

Price found within the past 48 hours. Click for updated prices.
MainStay Suites St. Louis - Galleria
The Cheshire
 White House at Grand Central
Crowne Plaza St. Louis Airport by IHG
St. Louis Union Station Hotel, Curio Collection by Hilton
Hotel Saint Louis, Autograph Collection
The Knight Center at Washington University
The Westin St. Louis
Hilton Garden Inn Chesterfield
Embassy Suites by Hilton St. Louis St. Charles
Home2 Suites by Hilton St. Louis Downtown
21C Museum Hotel St Louis
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Hotel Deals near your St. Louis Union Station Vacation

Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street St. Louis MO
9.4/10 Exceptional! (3,324 reviews)
Nice staff, clean rooms, dinner and breakfast for quests.

Reviewed on Jan 25, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Drury Inn & Suites St. Louis Union Station
3 out of 5
201 S 20th St St. Louis MO
9.2/10 Wonderful! (1,338 reviews)
Staff was very helpful and courteous. Looking forward to staying again.

Reviewed on Jan 24, 2026

Opens in a new windowDrury Inn & Suites St. Louis Union Station
Live by Loews - St.Louis
4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Jan 29 to Jan 30
$177 total
Jan 29 - Jan 30
Total with taxes and fees
9.2/10 Wonderful! (1,114 reviews)
Great check in staff... Parking valet attendant wonderful... Rooms clean, quiet and spacious!!! Highly recommend!!!

Reviewed on Jan 25, 2026

Opens in a new windowLive by Loews - St.Louis
Save an average of 15% on thousands of hotels when you're signed in
21C Museum Hotel St Louis
4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Feb 22 to Feb 23
$153 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (1,569 reviews)
Room was clean and staff was very informative. Top tier customer service

Reviewed on Jan 20, 2026

Opens in a new window21C Museum Hotel St Louis
Pear Tree Inn St. Louis Near Union Station
3 out of 5
2211 Market Street St. Louis MO
8.8/10 Excellent! (1,808 reviews)
Nice breakfast. Clean comfortable room.

Reviewed on Jan 22, 2026

Opens in a new windowPear Tree Inn St. Louis Near Union Station
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $118 total per night from Feb 1 to Feb 2
$118 total
Feb 1 - Feb 2
Total with taxes and fees
8.6/10 Excellent! (1,216 reviews)
Hotel is beautiful and the room was very nice.

Reviewed on Jan 23, 2026

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $188 total per night from Jan 30 to Jan 31
$188 total
Jan 30 - Jan 31
Total with taxes and fees
8.4/10 Very Good! (4,035 reviews)
Great location and vibe. I will definitely return

Reviewed on Jan 23, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $209 total per night from Jan 29 to Jan 30
$209 total
Jan 29 - Jan 30
Total with taxes and fees
8.4/10 Very Good! (1,005 reviews)
Everything it was amazing

Reviewed on Jan 20, 2026

Opens in a new windowSt. Louis Union Station Hotel, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.