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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Restaurant
Bar (on property)
Massages
Exterior
A modern lobby with a large glass sphere, seating areas, and a reception desk.

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, City Museum
    ‪5 min walk‬
  • Place, St. Louis Union Station
    ‪8 min walk‬
  • Place, Enterprise Center
    ‪8 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪20 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, 1 King Bed

9.0 out of 10
Wonderful
(118 reviews)
  • 309 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Luxury Double Room, 2 Queen Beds

A hotel room with two beds, a large window, a modern ceiling light, and a view of a staircase.

Luxury Double Room, 2 Queen Beds

9.4 out of 10
Exceptional
(36 reviews)
  • 423 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Room (Bunk Bed)

A hotel room with a bunk bed, a round table with a chair, a potted plant, and a colorful abstract painting on the wall.

Room (Bunk Bed)

8.4 out of 10
Very good
(7 reviews)
  • 237 sq ft
  • Sleeps 2
  • 1 Twin Bunk Bed
  • Free WiFi

View all photos for Loft, 2 Queen Beds

A hotel room with two beds, a large padded headboard, a flat-screen TV, a window with a city view, and a small side table with a plant.

Loft, 2 Queen Beds

9.0 out of 10
Wonderful
(2 reviews)
  • 431 sq ft
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, Accessible (Accessible)

10.0 out of 10
Exceptional
(1 review)
  • 269 sq ft
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed (21C)

A hotel room with a large bed, a desk, a chair, a nightstand, and a mirror.

Suite, 1 King Bed (21C)

  • 1119 sq ft
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Library)

  • City view
  • 732 sq ft
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | In-room safe, desk, laptop workspace, blackout drapes

Luxury Suite, 1 King Bed

9.4 out of 10
Exceptional
(3 reviews)
  • 549 sq ft
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Deluxe Room, 1 Double Bed, Accessible

A hotel room with two beds, a sofa, a TV, and a large abstract painting.

Deluxe Room, 1 Double Bed, Accessible

  • 388 sq ft
  • Sleeps 4
  • 1 Double Bed
  • Free WiFi

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Suite, 1 Double Bed, Accessible

  • 517 sq ft
  • Sleeps 2
  • 1 Double Bed
  • Free WiFi

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About the neighborhood

St. Louis

Located in Downtown West, 21C Museum Hotel St Louis is within a 10-minute walk of popular sights such as St. Louis Union Station and City Museum. This 4.5-star hotel welcomes guests with 104 rooms and conveniences like an indoor pool, free in-room WiFi, and a gym.

What's nearby

  • Washington Avenue Historic District - 2 min walk - 0.1 miles
  • City Museum - 5 min walk - 0.3 miles
  • St. Louis Union Station - 8 min walk - 0.4 miles
  • Enterprise Center - 8 min walk - 0.5 miles
  • St. Louis Aquarium at Union Station - 11 min walk - 0.6 miles

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 24 min drive

Restaurants

  • ‪Imo's Pizza Headquarters & Retail Store - ‬7 min walk
  • ‪Budweiser Kiel Club - ‬6 min walk
  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Guests of 21C Museum Hotel St Louis have access to an indoor pool, a gym, and a steam room. Valet parking is offered for USD 50 per day. The front desk is staffed 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Other amenities at this luxury hotel include free WiFi in public areas, meeting rooms, and a business center.
Guests can expect free WiFi and flat-screen TVs with cable channels. Bathrooms offer hair dryers, free toiletries, and bathrobes. Espresso makers, safes, and phones are also available. Change of towels is available on request.
Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

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Embassy Suites by Hilton St. Louis Downtown
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  • Pool
  • Breakfast included
  • Pet friendly
  • Restaurant
8.8 out of 10, Excellent, 1,309 reviews
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The price is $155
Jul 12 - Jul 13
Total with taxes and fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Non-plastic coffee stirrers available
  • Non-plastic drinking straws available
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 100 per accommodation, per stay
  • Dogs only
  • Service animals exempt from fees

Property payment types

Important information

Fees

  • Service fee: USD 5 per accommodation, per stay

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and outdoor lighting
  • Check-in: 4:00 PM—-11:00 AM
  • Check-out: 11:00 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers valet parking (fees apply).

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a fire extinguisher, a smoke detector, and outdoor lighting.

Additional information about polices, regulations, and more:

  • Reservations need to be made in advance for massage services. Contact the hotel at the phone number listed on your booking confirmation.
  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Is free cancellation available at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. If you'd like to learn more, look at the cancellation policy on Orbitz.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of Jul 2, 2026, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on Jul 12, 2026 start from $183, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to do close to 21C Museum Hotel St Louis ?

This hotel is situated in Downtown West, just steps from City Museum, and within a 10-minute walk of St. Louis Union Station and Enterprise Center. You'll also find Busch Stadium and Dome at America’s Center less than a mile away.

Will I be able to park at 21C Museum Hotel St Louis ?

Yes, valet parking is offered for USD 50 per day with in/out privileges.

Is there a spa available at 21C Museum Hotel St Louis ?

Spa services at the hotel include massages.

Does 21C Museum Hotel St Louis have luxury amenities?

Yes, guests can indulge in luxuries such as an indoor pool, a restaurant, and massages at this hotel.

Does 21C Museum Hotel St Louis include a casino at the property?

No, 21C Museum Hotel St Louis doesn't have a casino.

Will I find an indoor pool at 21C Museum Hotel St Louis ?

Yes, this hotel has an indoor pool.

What amenities will couples enjoy at 21C Museum Hotel St Louis ?

There are plenty of amenities for couples at this hotel, including a restaurant, an indoor pool, and a bar/lounge.

Are there hot tubs at 21C Museum Hotel St Louis ?

No, but guests can enjoy a steam room at this hotel.

Does 21C Museum Hotel St Louis have a restaurant with a breakfast menu?

Yes, 21C Museum Hotel St Louis serves a cooked-to-order breakfast each morning for a surcharge from its restaurant.

Will 21C Museum Hotel St Louis allow pets to stay for free?

Although they can't stay for free, dogs are welcome at 21C Museum Hotel St Louis for a fee of USD 100 per accommodation, per stay.

Are there connecting rooms at 21C Museum Hotel St Louis ?

No, there aren't connecting guestrooms at this hotel.

What is the closest airport to 21C Museum Hotel St Louis ?

The closest major airport to 21C Museum Hotel St Louis is St. Louis Lambert Intl. Airport (STL), which is 18.4 mi away (24 minutes by car). Another top airport is Belleville, IL (BLV-MidAmerica-St. Louis), which is located 25.9 mi away (32-minute drive).

Can I book a room with a balcony at 21C Museum Hotel St Louis ?

No, you won't find guestrooms with balconies at 21C Museum Hotel St Louis .

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1368 out of 1945 reviews
Rating 8 - Good. 297 out of 1945 reviews
Rating 6 - Okay. 143 out of 1945 reviews
Rating 4 - Poor. 64 out of 1945 reviews
Rating 2 - Terrible. 73 out of 1945 reviews

9.2/10

Cleanliness

9.0/10

Staff & service

9.0/10

Amenities

9.2/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Rebecca

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful hotel
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Absolutely beautiful, amazing breakfast, comfy bed!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Sheronda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fun hotel.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Crystal

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Gorgeous, clean, unique, and within walking distance of everything fun! Valets were so helpful and friendly, right off the bat. They set an excellent first impression. The hotel alone provided a fantastic experience with the art exhibit and the main floor entertainment options. The gym area was the best we have ever seen at a hotel. We were so pleased with our stay and the affordability of it all! We can’t wait to book again.
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Chad

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
A fantastic stay. Great breakfast and excellent pool area. Would stay again
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Donna

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel with a friendly staff. The on-site restaurant is a great spot fir a cocktail after a day of exploring.
Stayed 2 nights in Mar 2026
Verified

8/10 Good

Charles

Liked: Cleanliness, amenities
A very unique hotel with art center, excellent à la cart breakfast (included) and ample parking options.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful place, friendly staff! Enjoyed our stay and will definitely come back!!!
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Malisa

Liked: Cleanliness, staff & service, property conditions & facilities
It is a nice hotel
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Great place to stay. I recommend it and will stay again.
Stayed 1 night in Feb 2026
Verified

8/10 Good

Jawanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Helpful staff and fun environment…interesting art gallery and nearby Enterprise Center
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stay was great and the hotel was a close walk to Enterprise Center.
Stayed 1 night in Mar 2026
Verified

8/10 Good

Kevin

Liked: Cleanliness, staff & service, property conditions & facilities
Unique hotel, would stay again
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

RICHARD

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Outstanding hotel! Everything about it was great. Easy walks to Enterprise Center, to Busch Stadium and the Arch!
Stayed 2 nights in Mar 2026
Verified

8/10 Good

Muriel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room excellent and large with great decor and amenities like robes!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Kelly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We had a great stay at the Museum hotel! Place was gorgeous, room very clean & the staff was wonderful! Highly recommend!
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Darrell

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is the ONLY hotel that we stay at when we come to St. Louis!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Alex

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff!!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Stephanie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Gorgeous amenities. Room was tiptop shape! Food was good.
Stayed 3 nights in Mar 2026
Verified

8/10 Good

Kristen

Liked: Cleanliness, staff & service, amenities
Friendly staff, beautiful atmosphere, modern finishes.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Barry

Liked: Cleanliness, amenities, property conditions & facilities
Great atmosphere, excellent room accommodations. Staff at the Idlewolf restaurant inside the hotel were great, and the happy hour is excellent for the modest price. Will be staying again soon!
Stayed 3 nights in Feb 2026
Verified

10/10 Excellent

Hanna

Liked: Cleanliness, staff & service, amenities
The one of the best hotels in stl
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Kimbriel

Liked: Cleanliness, amenities, property conditions & facilities
Everything was great i can’t wait to stay again
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Ann

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful facility. Convenient to events
Stayed 5 nights in Mar 2026

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