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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with a fitness center and a steam room

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Indoor pool
1 bedroom, in-room safe, desk, laptop workspace
Lobby
Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • City Museum
    ‪6 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

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Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | 1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

  • 309 sq ft
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

  • 369 sq ft
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Room, 1 King Bed, Corner

  • 326 sq ft
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

  • 423 sq ft
  • Sleeps 4
  • 2 Queen Beds

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About the neighborhood

St. Louis

Located in Downtown West, 21C Museum Hotel St Louis is within a 10-minute walk of popular sights such as Enterprise Center and City Museum. This 4.5-star hotel welcomes guests with 104 rooms and conveniences like an indoor pool, free in-room WiFi, and a gym.

What's nearby

  • St. Louis Union Station - 6 min walk - 0.4 miles
  • Enterprise Center - 6 min walk - 0.4 miles
  • City Museum - 6 min walk - 0.4 miles
  • Busch Stadium - 14 min walk - 0.8 miles
  • Gateway Arch - 2 min drive - 1.1 miles

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with a fitness center and a steam room
Guests of 21C Museum Hotel St Louis have access to an indoor pool, a gym, and a steam room. Valet parking is offered for USD 50 per day. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and concierge services. Other amenities at this luxury hotel include free WiFi in public areas, meeting rooms, and a business center.
Guests can expect free WiFi and flat-screen TVs with cable channels. Bathrooms offer hair dryers, free toiletries, and bathrobes. Espresso makers, safes, and phones are also available. Change of towels is available on request.
Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

Languages

English

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 100 per accommodation, per stay
  • Dogs only
  • Service animals exempt from fees

Property payment types

Important information

Fees

  • Service fee: USD 5 per accommodation, per stay

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
  • Check-in: 4:00 PM—-11:00 AM
  • Check-out: 11:00 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers valet parking (fees apply).

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a smoke detector and outdoor lighting.

Additional information about polices, regulations, and more:

  • Reservations need to be made in advance for massage services. Contact the hotel at the phone number listed on your booking confirmation.
  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Is free cancellation available at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. If you'd like to learn more, look at the cancellation policy on Orbitz.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of Jun 15, 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on Jun 24, 2025 start from $246.05, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to do close to 21C Museum Hotel St Louis ?

This hotel is situated in Downtown West within a 10-minute walk of Enterprise Center and City Museum. You'll also find St. Louis Union Station and Busch Stadium less than a mile away.

Is parking available on site at 21C Museum Hotel St Louis ?

Yes, valet parking is offered for USD 50 per day with in/out privileges.

Is there a spa available at 21C Museum Hotel St Louis ?

Spa services at the hotel include massages.

Does 21C Museum Hotel St Louis include a casino at the property?

No, 21C Museum Hotel St Louis doesn't have a casino.

Will I find an indoor pool at 21C Museum Hotel St Louis ?

Yes, this hotel has an indoor pool.

What amenities will couples enjoy at 21C Museum Hotel St Louis ?

There are plenty of amenities for couples at this hotel, including an indoor pool, a bar, and a restaurant.

Are there hot tubs at 21C Museum Hotel St Louis ?

No, but this hotel does have a steam room.

Does 21C Museum Hotel St Louis have a restaurant with a breakfast menu?

Yes, 21C Museum Hotel St Louis serves a cooked-to-order breakfast each morning for a surcharge from its restaurant.

Will 21C Museum Hotel St Louis allow pets to stay for free?

Although they can't stay for free, dogs are welcome at 21C Museum Hotel St Louis for a fee of USD 100 per accommodation, per stay.

Are there connecting rooms at 21C Museum Hotel St Louis ?

No, this hotel doesn't feature connecting guestrooms.

What is the closest airport to 21C Museum Hotel St Louis ?

The closest major airport to 21C Museum Hotel St Louis is St. Louis Lambert Intl. Airport (STL), which is 18.4 mi away (26 minutes by car). Another top airport is St. Louis, MO (SUS-Spirit of St. Louis), which is located 25.8 mi away (32-minute drive).

Are there rooms with balconies at 21C Museum Hotel St Louis ?

No, you won't find guestrooms with balconies at 21C Museum Hotel St Louis .

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 848 out of 1175 reviews
Rating 8 - Good. 180 out of 1175 reviews
Rating 6 - Okay. 66 out of 1175 reviews
Rating 4 - Poor. 35 out of 1175 reviews
Rating 2 - Terrible. 46 out of 1175 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Mary

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved this hotel!
Stayed 1 night in Jun 2025

10/10 Excellent

Michelle

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing
Stayed 2 nights in Apr 2025

10/10 Excellent

Bryan

Traveled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Great boutique hotel in downtown St. Louis, the hotel was busy when we checked in and the front desk staff was a bit harried, but they gave us the essential information we needed. The art gallery on the second floor was a great addition to our stay, as was the on sight restaurant, The Idol Wolf, amazing food, and service. The hotel itself has a very cool, and eclectic vibe, but is beginning to look a little “run down”. But overall a good experience, we will definitely stay here again if we are ever in the area.
Stayed 1 night in Mar 2025

10/10 Excellent

Lisa

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

chastity

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really clean and updated. The museum on the 2nd floor was nice to browse. Valet guys were funny and friendly. The gal at check in was not as friendly. Would stay here again for convenience to concerts, sporting events, etc.
Stayed 1 night in Mar 2025

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

March 21c couples stay

The hotel, bar, restaurants and art were amazing. Would definitely stay here again. Some improvements; need a hair dryer in room without asking, need hooks in bathroom and need higher quality toilet paper.
Stayed 2 nights in Mar 2025

10/10 Excellent

Brandi

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Mar 2025

10/10 Excellent

Latisha

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice and comfortable hotel.
Stayed 2 nights in Jan 2025

10/10 Excellent

Amy

Stayed 4 nights in Feb 2025

10/10 Excellent

Jonathan

Stayed 5 nights in Feb 2025

6/10 Okay

Erin

Traveled with family
Disliked: Cleanliness
It was disappointing to walk into hotel and see dirty carpeted stairs, glasses from the night before left in the pool and health club areas and a bathroom barn door that didn't close all the way in our room. No towels were available for pool use, we were told by the rude attendant to use our room towels and it was quite a process to get extra clean towels to use after showers. This hotel has a lot of potential but was underwhelming. I would not stay here again.
Stayed 1 night in Mar 2025

8/10 Good

Andrew

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Cool, hip downtown spot!

First time staying here and aside from a few issues, it was a worthwhile stay. Hotel is an old YMCA that has been modernized and upgraded in a major way! Food options are worthy and showcased art is a nice bonus. Pool is also great! Except for a few “misses”this place would be Excellent.
Stayed 4 nights in Feb 2025

6/10 Okay

Jerry, Grimes

Stayed 1 night in Mar 2025

10/10 Excellent

Alexander

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I like
Stayed 2 nights in Feb 2025

10/10 Excellent

Griffin

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

8/10 Good

Deana

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good for a fun getaway weekend

The hotel is charming, built in the old YMCA building with a restored fitness pool, hot tub and sauna. Be aware that there is no free breakfast, hotels.com will list it was an option for an extra $3 but there is no free buffet style breakfast but there is an overpriced trendy breakfast cafe in the hotel, the coffee was great but the food took an hour to make and was not worth the price in my opinion. The tv in the room also does not have streaming services, you have to connect to their wifi and stream from your phone which is absolutely ridiculous in my opinion. Just provide simple tv options that play netflix/spotify on the tv.
Stayed 1 night in Feb 2025

8/10 Good

Emily

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel is beautiful, bar and restaurant are lovely, the hot tub, pool, and fitness area were great. The housekeeping was not thorough (forgot to leave coffee cups day 2, and didn't have conditioner). I had to go down to the desk to get these as they didn't have staff available to bring them up. Otherwise, great.
Stayed 2 nights in Mar 2025

10/10 Excellent

Lauren

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great for hockey games!
Stayed 1 night in Jan 2025

10/10 Excellent

Chris

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Mar 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities
Beautiful hotel, friendly staff. Great pool, lobby and coffee shop
Stayed 1 night in Mar 2025

10/10 Excellent

SARAH

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to a lot of things. Great location!
Stayed 1 night in Mar 2025

10/10 Excellent

Deion

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Feb 2025

10/10 Excellent

Charvez

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice room that uses its space very well. Love that there is a museum in the hotel and the restaurants were delicious as well!
Stayed 2 nights in Feb 2025

10/10 Excellent

Brenda

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Rooms were clean, modern and comfortable. Great experience. Staff were friendly and helpful. Would definitely stay at this hotel again and have recommended it to others.
Stayed 1 night in Feb 2025

10/10 Excellent

Randi, Las Vegas

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 4 nights in Feb 2025