Business Hotels in South Indianapolis, IN
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured South Indianapolis Business Hotels

La Quinta Inn & Suites by Wyndham Indianapolis South
5120 Victory Drive Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$92 nightly
The price is $107 total per night
$107 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Indianapolis South, guests have access to a gym, free WiFi in public areas, and meeting rooms. If you drive, take advantage of free parking. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included

Comfort Inn Indianapolis South I-65
3514 S Keystone Avenue Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$62 nightly
The price is $73 total per night
$73 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
At Comfort Inn Indianapolis South I-65, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk has multilingual staff standing by 24 hours a day to assist with dry cleaning/laundry and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Country Inn & Suites by Radisson, Indianapolis South, IN
4325 Southport Crossings Way Indianapolis IN
Free Cancellation
$88 nightly
The price is $103 total per night
$103 total
Jan 19 - Jan 20, 2026
Total with taxes and fees
Renovated in 2016, Country Inn & Suites by Radisson, Indianapolis South, IN offers an indoor pool, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include laundry facilities, an ATM, and a fireplace in the lobby.
Pool
Breakfast included

Holiday Inn Express Indianapolis South by IHG
5151 S East St Indianapolis IN
Free Cancellation
$77 nightly
The price is $90 total per night
$90 total
Dec 27 - Dec 28
Total with taxes and fees
At Holiday Inn Express Indianapolis South by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and free newspapers.
Pool
Breakfast included

Comfort Suites Southport
4125 Kildeer Dr Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $98 total per night
$98 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Comfort Suites Southport have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.

Baymont by Wyndham Indianapolis South
4402 E Creek View Rd Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $77 total per night
$77 total
Jan 13 - Jan 14, 2026
Total with taxes and fees
Guests of Baymont by Wyndham Indianapolis South enjoy a 24-hour gym, free WiFi in public areas, and meeting rooms. Free parking is available if you drive. The 24-hour front desk has staff always at the ready. Additional amenities include conference space, a 24-hour business center, and express check-in.
Breakfast included
Pet friendly

Hampton Inn by Hilton Indianapolis-South
7045 Mcfarland Blvd Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$91 nightly
The price is $106 total per night
$106 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Hampton Inn by Hilton Indianapolis-South, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, concierge services, and securing valuables. Additional amenities include conference space, coffee/tea in a common area, and express check-in.
Pool
Breakfast included

Hilton Garden Inn Indianapolis South/Greenwood
5255 Noggle Way Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $92 total per night
$92 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Hilton Garden Inn Indianapolis South/Greenwood, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with concierge services, dry cleaning/laundry, and securing valuables. Additional amenities include conference space, coffee/tea in a common area, and express check-out.
Pool
Pet friendly

Holiday Inn Express Indianapolis - Southeast by IHG
5302 Victory Dr Indianapolis IN
Free Cancellation
$78 nightly
The price is $91 total per night
$91 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Guests staying at Holiday Inn Express Indianapolis - Southeast by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. Multilingual staff at the 24-hour front desk can assist with luggage storage, concierge services, and securing valuables. Additional amenities include conference space, a 24-hour business center, and express check-out.
Pool
Breakfast included

Red Roof Inn Indianapolis South
5221 Victory Dr Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$49 nightly
The price is $57 total per night
$57 total
Dec 29 - Dec 30
Total with taxes and fees
Guests of Red Roof Inn Indianapolis South enjoy free WiFi in public areas, coffee in a common area, and a TV in a common area. Free parking is included with your stay. The 24-hour front desk has staff always at the ready. Additional amenities include a vending machine and a water dispenser.

Super 8 by Wyndham Indianapolis/Southport Rd
4033 East Southport Rd Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $70 total per night
$70 total
Jan 13 - Jan 14, 2026
Total with taxes and fees
Super 8 by Wyndham Indianapolis/Southport Rd features free WiFi in public areas, coffee in a common area, and express check-out. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a TV in a common area and a vending machine.

Super 8 by Wyndham Indianapolis South
450 Bixler Road Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$57 nightly
The price is $67 total per night
$67 total
Dec 29 - Dec 30
Total with taxes and fees
Super 8 by Wyndham Indianapolis South features free WiFi in public areas, a 24-hour business center, and express check-out. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include an ATM and a TV in a common area.

Best Western Indianapolis South
4450 Southport Crossing Dr Indianapolis IN
Best Western Indianapolis South features an indoor pool, an outdoor pool, and a gym. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include free WiFi in public areas, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Courtyard by Marriott Indianapolis South
4650 Southport Crossing Drive Indianapolis IN
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $121 total per night
$121 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Guests of Courtyard by Marriott Indianapolis South enjoy a 24-hour gym, free WiFi in public areas, and a business center. A stay here includes free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a refrigerator in a common area, a meeting room, and a computer station.

Fairfield Inn by Marriott Indianapolis South
4504 Southport Crossing Rd Indianapolis IN
Fairfield Inn by Marriott Indianapolis South features an outdoor pool, a 24-hour gym, and meeting rooms. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, free newspapers, and a water dispenser.
Don't see what you're looking for?
See all available properties in South Indianapolis
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Indianapolis hotels essential information
Accommodation | 2,508 hotels |
|---|---|
Lowest Price | $57 |
Highest Price | $121 |
Popular hotels | La Quinta Inn & Suites by Wyndham Indianapolis South, Comfort Inn Indianapolis South I-65, Country Inn & Suites by Radisson, Indianapolis South, IN, Holiday Inn Express Indianapolis South by IHG, Comfort Suites Southport, Baymont by Wyndham Indianapolis South, Hampton Inn by Hilton Indianapolis-South, Hilton Garden Inn Indianapolis South/Greenwood, Holiday Inn Express Indianapolis - Southeast by IHG, Red Roof Inn Indianapolis South, Super 8 by Wyndham Indianapolis/Southport Rd, Super 8 by Wyndham Indianapolis South, Best Western Indianapolis South, Courtyard by Marriott Indianapolis South, Fairfield Inn by Marriott Indianapolis South |
Recent Business Hotels Reviews

Bottleworks Hotel
5/5 Excellent
"Wonderful hotel. Unique, beautiful, clean and luxurious. Would love to come back. Great walking location as well."
A verified traveler stayed at Bottleworks Hotel
Posted 2 days ago
More to Explore
- Hotels near Smock Golf Course
- B&B in Greenwood
- Cottages in Greenwood
- Guest Houses in Greenwood
- Hostels in Greenwood
- Greenwood Hotels
- Motels in Greenwood
- Vacation Homes in Greenwood
- Hotels near Gainbridge Fieldhouse
- Hotels near Key Stadium
- Hotels near Lucas Oil Stadium
- Indianapolis Hotels
- 5 Star Hotels in Beech Grove
- Golf Resorts & in Beech Grove
- La Quinta Inn & Suites Hotels in Beech Grove
- Luxury Hotels in Beech Grove
- Pet Friendly Hotels in Beech Grove
- Red Roof Inn Hotels in Beech Grove
- Beech Grove Hotels
- Motels in Beech Grove
- 5 Star Hotels in South Village
- Hotels near Greatimes Familiy Fun Park
- Cheap Hotels in Southdale
- Golf Resorts & in Southdale
- Green Hotels in Southdale
- Historic Hotels in Southdale
- Hotels with WiFi in Southdale
- Hotels with a Lazy River in Southdale
- Hotels with Bar in Southdale
- Hotels with an Indoor Pool in Southdale
- Luxury Hotels in Southdale
- 3 Star Hotels in Southport
- Adventure Hotels in Southport
- Arcade Hotels in Southport
- Boutique Hotels in Southport
- Casino Resorts & in Southport
- Business Hotels in Southport
- Kid Friendly Hotels in Southport
- Golf Resorts & in Southport
- Hotels with Suites in Southport
- Hotels with Airport Transfers in Southport
- Hotels with Balconies in Southport
- Hotels with Bar in Southport
- Hotels with Childcare in Southport
- Hotels with Hot Tubs in Southport
- Hotels with an Indoor Pool in Southport
- Hotels with Room Service in Southport
- Hotels on the Lake in Southport
- Pet Friendly Hotels in Southport
- Spa Resorts & in Southport
- Southport Hotels
- Hotels near Greenwood Park Mall
- Hotels near Indiana Baptist College
- Hotels near Great Times Fun Park
- Flights to Greenwood
- Flights from Green Bay to Greenwood
- Flights from Charlotte to Greenwood
- Flights from Dallas to Greenwood
- Flights from Houston to Greenwood
- Flights from Los Angeles to Greenwood
- Flights from Minneapolis - St. Paul to Greenwood
- Flights from Phoenix to Greenwood
- Flights from Raleigh to Greenwood
- Flights from Edmonton to Greenwood
- Flights from Jacksonville to Greenwood
- Flights from Fort Lauderdale to Greenwood
- Flights from Newark to Greenwood
- Flights from Madison to Greenwood
- Flights from Shreveport to Greenwood
- Flights from Sioux Falls to Greenwood
- Flights from Brainerd to Greenwood
- Flights from Winnipeg to Greenwood
- Flights from Greenwood
- Flights to Indianapolis
- Flights from Atlanta to Indianapolis
- Flights from Boston to Indianapolis
- Flights from Charlotte to Indianapolis
- Flights from Chicago to Indianapolis
- Flights from Dallas to Indianapolis
- Flights from Denver to Indianapolis
- Flights from Detroit to Indianapolis
- Flights from Houston to Indianapolis
- Flights from Indianapolis
- Flights from Las Vegas to Indianapolis
- Flights from Los Angeles to Indianapolis
- Flights from Minneapolis - St. Paul to Indianapolis
- Flights from New York to Indianapolis
- Flights from Orlando to Indianapolis
- Flights from Philadelphia to Indianapolis
- Flights from Phoenix to Indianapolis
- Flights from San Francisco to Indianapolis
- Flights from Seattle to Indianapolis
- Flights from Washington to Indianapolis
- Flights from Newark to Indianapolis
- Flights from Tampa to Indianapolis
- Flights to Beech Grove
- Flights from Beech Grove


