San Diego Vacation Homes

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Featured Vacation Homes in San Diego

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in San Diego

    San Diego Mission Bay Resort

    San Diego Mission Bay Resort

    1775 E Mission Bay Dr, San Diego, CA
    $218 nightly
    The price is $251 total per night from May 14 to May 15
    $251 total
    May 14 - May 15
    Total includes taxes and fees
    8.2/10 Very Good! (1,209 reviews)
    The Dana on Mission Bay

    The Dana on Mission Bay

    1710 W Mission Bay Dr, San Diego, CA
    $179 nightly
    The price is $206 total per night from May 26 to May 27
    $206 total
    May 26 - May 27
    Total includes taxes and fees
    8.8/10 Excellent! (3,379 reviews)
    Days Inn by Wyndham San Diego Hotel Circle

    Days Inn by Wyndham San Diego Hotel Circle

    543 Hotel Circle S, San Diego, CA
    $107 nightly
    The price is $123 total per night from May 18 to May 19
    $123 total
    May 18 - May 19
    Total includes taxes and fees
    7.6/10 Good! (2,170 reviews)

San Diego Vacation Homes

Book vacation homes in San Diego
Next time you take a group getaway top San Diego, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of San Diego vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every San Diego vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in San Diego; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a San Diego rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to San Diego is sure to be a winner.

San Diego Vacation Homes essential information

Accommodation
2601 Vacation Homes
Lowest Price
$123 total
Highest Price
$693 total
Popular accommodation
Isthmus Oasis at Belmont Park, 2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay, Beachside Getaway with Rooftop Spa & Parking, Beautiful Normal Heights Living, Serene 4 Bedroom with Canyon and Ocean Views, Cozy beach house just one house off from beach and boardwalk, Adorable Spanish style casita in fantastic area of Historic North Park, Storybook Beach House 2 blocks from the Beach or Mission Bay with Pool & Hot tub, Ocean Front Luxury Beach House #5 - Sleeps 6 - Penthouse View - 180 degrees Full