San Diego Vacation Homes

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Featured Vacation Homes in San Diego

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in San Diego

    Sheraton San Diego Resort

    Sheraton San Diego Resort

    1380 Harbor Island Dr San Diego CA
    $138 nightly
    The price is $158 total per night from Dec 23 to Dec 24
    $158 total
    Dec 23 - Dec 24
    Total with taxes and fees
    8.2/10 Very Good! (3,155 reviews)
    Lafayette Hotel & Club

    Lafayette Hotel & Club

    2223 El Cajon Blvd San Diego CA
    $229 nightly
    The price is $263 total per night from Dec 29 to Dec 30
    $263 total
    Dec 29 - Dec 30
    Total with taxes and fees
    9.2/10 Wonderful! (1,341 reviews)
    Hard Rock Hotel San Diego

    Hard Rock Hotel San Diego

    207 5th Ave San Diego CA
    $210 nightly
    The price is $243 total per night from Jan 1 to Jan 2
    $243 total
    Jan 1 - Jan 2, 2026
    Total with taxes and fees
    8.8/10 Excellent! (3,153 reviews)

San Diego Vacation Homes

Book vacation homes in San Diego
Next time you take a group getaway top San Diego, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of San Diego vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every San Diego vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in San Diego; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a San Diego rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to San Diego is sure to be a winner.

San Diego Vacation Homes essential information

Accommodation
2557 Vacation Homes
Lowest Price
$158
Highest Price
$318
Popular accommodation
3 bdr, 3 bath Home Walk to bay, ocean, restaurants and shops!, Palisades By the Bay Whole House Rental, Fox Canyon Hideaway-San Diego, Storybook Beach House 2 blocks from the Beach or Mission Bay with Pool & Hot tub, Perfect Family Vacation Home In Crown Point Pacific Beach , Clean! Best DECK... VIEW... 1 min to sand. PARKING... BIKES. Cal King., Relax, recharge and enjoy panoramic sunset views over the bay and ocean in this luxurious home, Beachcomber Bliss Sleeps 4 Free Parking 2BLKS to Ocean, Beautiful Normal Heights Living

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