Hotels near Main Street Cultural District

Guests of Comfort Inn and Suites Ames near ISU Campus have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include a 24-hour business center, laundry facilities, and a vending machine.

At GrandStay Hotel & Suites, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and express check-out.

Guests of SpringHill Suites by Marriott Ames have access to an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a meeting room and laundry facilities.

Guests of Home2 Suites By Hilton Ames enjoy features like an indoor pool, free WiFi in public areas, and laundry facilities. You can take advantage of free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests.

Guests of Microtel Inn & Suites by Wyndham Ames enjoy a 24-hour gym, free WiFi in public areas, and a 24-hour business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include coffee/tea in a common area, a meeting room, and express check-out.

At Best Western Plus University Park Inn & Suites, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, a business center, and coffee/tea in a common area.

At Gateway Hotel and Conference Center at Iowa State University, guests enjoy an indoor pool, a gym, and a sauna. You can put free parking to good use if you drive. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area and litter boxes. Additional amenities include free WiFi in public areas, a hot tub, and a conference center.

AmericInn by Wyndham Ames offers an indoor pool, free WiFi in public areas, and a hot tub. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with luggage storage and concierge services. Additional amenities include a business center, a meeting room, and a computer station.

Renovated in 2025, Spark by Hilton Ames offers an indoor pool, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include conference space, coffee/tea in a common area, and a vending machine.