Hotels near Main Street Cultural District
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Check prices close to Main Street Cultural District for tomorrow night, Nov 4 - Nov 5Featured Hotels near Main Street Cultural District

Days Inn by Wyndham Ames
229 S. Duff Avenue Ames IA
Free Cancellation
Reserve now, pay when you stay
0.38 mi from Main Street Cultural District
$77 nightly
The price is $86 total per night
$86 total
Nov 26 - Nov 27
Total with taxes and fees
Guest of Days Inn by Wyndham Ames enjoy features like conference space, a 24-hour business center, and coffee in a common area. There's free parking if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include express check-in, laundry facilities, and a vending machine.
Breakfast included
Parking included

Comfort Inn and Suites Ames near ISU Campus
603 South 16th Street Ames IA
Free Cancellation
Reserve now, pay when you stay
1.1 mi from Main Street Cultural District
$87 nightly
The price is $97 total per night
$97 total
Nov 24 - Nov 25
Total with taxes and fees
Guests of Comfort Inn and Suites Ames near ISU Campus have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include a 24-hour business center, laundry facilities, and a vending machine.
Pool
Breakfast included

GrandStay Hotel & Suites
1606 S Kellogg Ave Ames IA
Free Cancellation
Reserve now, pay when you stay
1.22 mi from Main Street Cultural District
$87 nightly
The price is $97 total per night
$97 total
Dec 2 - Dec 3
Total with taxes and fees
At GrandStay Hotel & Suites, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and express check-out.
Pool
Breakfast included

Sonesta Essential Ames
1400 S Dayton Place Ames IA
Free Cancellation
Reserve now, pay when you stay
2.02 mi from Main Street Cultural District
$63 nightly
The price is $70 total per night
$70 total
Nov 9 - Nov 10
Total with taxes and fees
At Sonesta Essential Ames, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. Other amenities at this family-friendly hotel include a 24-hour business center, coffee/tea in a common area, and laundry facilities.
Pool
Breakfast included

Microtel Inn & Suites by Wyndham Ames
2216 Se 16th St Ames IA
Free Cancellation
Reserve now, pay when you stay
2.04 mi from Main Street Cultural District
$68 nightly
The price is $76 total per night
$76 total
Nov 26 - Nov 27
Total with taxes and fees
Guests of Microtel Inn & Suites by Wyndham Ames enjoy a 24-hour gym, free WiFi in public areas, and a 24-hour business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include coffee/tea in a common area, a meeting room, and express check-out.
Breakfast included
Pet friendly

Best Western Plus University Park Inn & Suites
2500 University Blvd. Ames IA
2.07 mi from Main Street Cultural District
$74 nightly
The price is $83 total per night
$83 total
Nov 8 - Nov 9
Total with taxes and fees
At Best Western Plus University Park Inn & Suites, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, a business center, and coffee/tea in a common area.
Pool
Hot Tub

Gateway Hotel and Conference Center at Iowa State University
2100 Green Hills Drive Ames IA
2.1 mi from Main Street Cultural District
$81 nightly
The price is $91 total per night
$91 total
Nov 15 - Nov 16
Total with taxes and fees
At Gateway Hotel and Conference Center at Iowa State University, guests enjoy an indoor pool, a gym, and a sauna. You can put free parking to good use if you drive. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area and litter boxes. Additional amenities include free WiFi in public areas, a hot tub, and a conference center.
Pool
Hot Tub

Country Inn & Suites by Radisson, Ames, IA
2605 Se 16th St Ames IA
Free Cancellation
2.15 mi from Main Street Cultural District
$75 nightly
The price is $84 total per night
$84 total
Nov 23 - Nov 24
Total with taxes and fees
Guests staying at Country Inn & Suites by Radisson, Ames, IA enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and luggage storage. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

Spark by Hilton Ames
2609 University Blvd Ames IA
2.19 mi from Main Street Cultural District
$89 nightly
The price is $100 total per night
$100 total
Nov 10 - Nov 11
Total with taxes and fees
Renovated in 2025, Spark by Hilton Ames offers an indoor pool, free WiFi in public areas, and meeting rooms. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include conference space, coffee/tea in a common area, and a vending machine.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Main Street Cultural District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Main Street Cultural District hotels essential information
Accommodation | 712 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $100 |
Popular hotels | Gateway Hotel and Conference Center at Iowa State University, Best Western Plus University Park Inn & Suites, Comfort Inn and Suites Ames near ISU Campus, Days Inn by Wyndham Ames, GrandStay Hotel & Suites, Sonesta Essential Ames, Spark by Hilton Ames, Country Inn & Suites by Radisson, Ames, IA, Microtel Inn & Suites by Wyndham Ames |
Recent Reviews

Gateway Hotel and Conference Center at Iowa State University
5/5 Excellent
"The restaurant and bar are beautiful and the staff is excellent."
A verified traveler stayed at Gateway Hotel and Conference Center at Iowa State University
Posted 18 hours ago

Comfort Inn and Suites Ames near ISU Campus
4/5 Good
"Enjoyable stay"
A verified traveler stayed at Comfort Inn and Suites Ames near ISU Campus
Posted 6 days ago
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