COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Compare La Mesa Guest House Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Guest Houses in La Mesa

Don't see what you're looking for?
See all available properties in La Mesa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in La Mesa

    Holiday Inn La Mesa, an IHG Hotel

    Holiday Inn La Mesa, an IHG Hotel

    8000 Parkway Dr, La Mesa, CA
    The price is $72 per night from Apr 19 to Apr 20
    3.7/5Good! (37 reviews)
    Holiday Inn La Mesa, an IHG Hotel
    Heritage Inn La Mesa

    Heritage Inn La Mesa

    7851 Fletcher Pkwy, La Mesa, CA
    The price is $75 per night from May 11 to May 12
    2.8/5 (25 reviews)
    Heritage Inn La Mesa
    Best Western Plus La Mesa San Diego

    Best Western Plus La Mesa San Diego

    9550 Murray Dr, La Mesa, CA
    The price is $109 per night from Apr 18 to Apr 19
    4/5Very Good! (49 reviews)
    Best Western Plus La Mesa San Diego