Orangeburg County Vacation Rentals

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Top cities in Orangeburg County

Claflin University, located in Orangeburg, South Carolina, was founded in 1869 by Alonzo Webster (1818-1887), a Vermont minister. Webster came to South Carolina to teach at the Baker Bible Institute in Charleston training African American ministers for the Methodist Episcopal Church (today the United Methodist Church). In 1869 he received a charter from the state of South Carolina to establish a college that would prepare freed slaves for the responsibilities of citizenship. The first charter banned discrimination among the faculty, staff and students, making the Academy the first South Carolina university open to all regardless of race. Nonetheless, all of the students at the Academy were African American.
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Orangeburg

Orangeburg

Orangeburg County Vacation Rentals

Bells Marina & Resort

Bells Marina & Resort

2.5 out of 5
12907 Old Number Six Hwy, Eutawville, SC
$97 nightly
The price is $107 total per night
$107 total
Aug 21 - Aug 22
Total includes taxes and fees
Renovated in 2025, Bells Marina & Resort offers a marina, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk has multilingual staff that can answer questions about the accommodations, services, and more. Other amenities at this golf aparthotel include conference space, laundry facilities, and a picnic area.
Pet friendly
Parking included
Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property

$185 nightly
The price is $205 total per night
$205 total
Aug 21 - Aug 22
Total includes taxes and fees
At this cottage, guests have access to features like laundry facilities.
Kitchen
Washer
Private Dock + Pool Table: Lake Marion Getaway

Private Dock + Pool Table: Lake Marion Getaway

At this vacation home, guests have access to an arcade/game room, laundry facilities, and a garden. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer
Charming 2 Bedroom Waterfront Lake Marion Condo

Charming 2 Bedroom Waterfront Lake Marion Condo

This condo features an outdoor pool and laundry facilities.
Pool
Kitchen
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive, Santee, SC
Guests staying at Wyndham Vacation Resorts Lake Marion enjoy features like an outdoor pool. Free parking is included with your stay.
Pool
Kitchen
Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.

$136 nightly
The price is $151 total per night
$151 total
Aug 25 - Aug 26
Total includes taxes and fees
Guests of this cottage enjoy features like a water park and laundry facilities.
Kitchen
Washer
Waterfront King Beds Pet Friendly Deck Home with Dock & Views.

Waterfront King Beds Pet Friendly Deck Home with Dock & Views.

Guests staying at this apartment have access to laundry facilities, barbecue grills, and a garden.
Kitchen
Washer
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

$298 nightly
The price is $330 total per night
$330 total
Aug 21 - Aug 22
Total includes taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer
Lake Marion Getaway!

Lake Marion Getaway!

2 out of 5
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
Kitchen
Washer
The Bunkhouse at St Julien - Vintage Waterfront Lake House

The Bunkhouse at St Julien - Vintage Waterfront Lake House

Guests of this vacation home enjoy access to a water park, laundry facilities, and a garden. This family-friendly vacation home also has barbecue grills.
Kitchen
Pet friendly
Relax by Lake Marion - A lake home with you in mind.

Relax by Lake Marion - A lake home with you in mind.

At this vacation home, guests have access to features like laundry facilities. This family-friendly vacation home also has barbecue grills.
Kitchen
Washer
Charming 3-bedroom house in Vance with WiFi and beautiful lake view

Charming 3-bedroom house in Vance with WiFi and beautiful lake view

At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Washer
Dryer
Lake Marion Lakehouse with 180° lake view

Lake Marion Lakehouse with 180° lake view

Guests of this vacation home enjoy access to a water park, laundry facilities, and barbecue grills. This family-friendly vacation home also has a garden.
Kitchen
Washer
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

At this vacation home, guests have access to an arcade/game room, laundry facilities, and barbecue grills. This beach vacation home also has a garden.
Kitchen
Washer
Archie's Lake Daze Cottage

Archie's Lake Daze Cottage

Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
Kitchen
Washer
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer
Welcome to our 5-bedroom home located in charming Lexington, S.C.

Welcome to our 5-bedroom home located in charming Lexington, S.C.

At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Washer
Dryer
WHITE KNOLL BUNGALOW

WHITE KNOLL BUNGALOW

2 out of 5
At this vacation home, guests have access to features like laundry facilities.
Washer
Dryer
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Orangeburg County

    Tru By Hilton Santee

    Tru By Hilton Santee

    263 Britain St. and 273 Britain St., Santee, SC
    $101 nightly
    The price is $112 total per night from Aug 26 to Aug 27
    $112 total
    Aug 26 - Aug 27
    Total includes taxes and fees
    9/10 Wonderful! (502 reviews)
    Baymont by Wyndham Santee

    Baymont by Wyndham Santee

    249 Britain Street, Santee, SC
    $75 nightly
    The price is $83 total per night from Aug 21 to Aug 22
    $83 total
    Aug 21 - Aug 22
    Total includes taxes and fees
    7.8/10 Good! (1,330 reviews)
    Super 8 by Wyndham, Orangeburg

    Super 8 by Wyndham, Orangeburg

    3608 Saint Matthews Rd, Orangeburg, SC
    $58 nightly
    The price is $64 total per night from Aug 24 to Aug 25
    $64 total
    Aug 24 - Aug 25
    Total includes taxes and fees
    6.6/10 (842 reviews)

Orbitz makes it easy to find vacation rentals in Orangeburg County 

🏠 What is the best price for a Orangeburg County vacation rental?


Orangeburg County rentals range between $64 and $330 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in Orangeburg County can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next Orangeburg County getaway. Orbitz filters your search results so you can find the best Orangeburg County vacation rental for you. We have tons of options.


🏠 Are cancellations free on Orangeburg County vacation rentals with Orbitz?


You may be able to cancel or amend your Orangeburg County vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in Orangeburg County?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in Orangeburg County by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in Orangeburg County?


When you book a Orangeburg County vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in Orangeburg County?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across Orangeburg County—with plenty of hidden gems. We also have plenty of inventory in Orangeburg County main cities and near popular attraction spots.


🏠 Why should I book my Orangeburg County vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream Orangeburg County vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


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