Orangeburg County Vacation Rentals

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top cities in Orangeburg County

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina
Vacation RentalsVacation Rentals
Vacation RentalsVacation Rentals

Orangeburg

Orangeburg

Orangeburg County Vacation Rentals

Bells Marina & Resort

Bells Marina & Resort

2.5 out of 5
12907 Old Number Six Hwy Eutawville SC
$108 nightly
The price is $120 total per night
$120 total
Mar 8 - Mar 9
Total with taxes and fees
Renovated in 2025, Bells Marina & Resort offers a marina, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk has multilingual staff that can answer questions about the accommodations, services, and more. Other amenities at this golf aparthotel include conference space, laundry facilities, and barbecue grills.
Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property

Holly Hill SC
$195 nightly
The price is $216 total per night
$216 total
Mar 23 - Mar 24
Total with taxes and fees
At this cottage, guests have access to features like laundry facilities.
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee SC
$337 nightly
The price is $374 total per night
$374 total
Mar 12 - Mar 13
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Lake Home walking distance to Marina and 2 more boat landings within a Mile!

Lake Home walking distance to Marina and 2 more boat landings within a Mile!

Eutawville SC
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Waterfront King Beds Pet Friendly Deck Home with Dock & Views.

Waterfront King Beds Pet Friendly Deck Home with Dock & Views.

Eutawville SC
Guests staying at this apartment have access to laundry facilities, a garden, and barbecue grills.
The Bunkhouse at St Julien - Vintage Waterfront Lake House

The Bunkhouse at St Julien - Vintage Waterfront Lake House

Eutawville SC
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
Lake Marion - Majestic Big Water View!

Lake Marion - Majestic Big Water View!

Santee SC
At this condo, guests have access to an outdoor pool, laundry facilities, and barbecue grills.
Lake Marion Lakehouse with 180° lake view

Lake Marion Lakehouse with 180° lake view

Elloree SC
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Summerton SC
Guests staying at this vacation home enjoy a gym, an arcade/game room, and laundry facilities. Other amenities at this family-friendly vacation home include a garden and barbecue grills.
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Summerton SC
$158 nightly
The price is $176 total per night
$176 total
Mar 10 - Mar 11
Total with taxes and fees
At this cabin, guests have access to features like laundry facilities.
Beautiful Cottage between Lake Moultrie and Lake Marion

Beautiful Cottage between Lake Moultrie and Lake Marion

Cross SC
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Summerton SC
$455 nightly
The price is $505 total per night
$505 total
Mar 22 - Mar 23
Total with taxes and fees
At this vacation home, guests have access to an arcade/game room, laundry facilities, and a garden. This beach vacation home also has barbecue grills.
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

Summerton SC
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
Jewel on the Lake - Relaxing Lakefront Home

Jewel on the Lake - Relaxing Lakefront Home

Manning SC
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Manning SC
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Lake Moultrie Home With Private Boat Ramp

Lake Moultrie Home With Private Boat Ramp

Moncks Corner SC
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
Cottage Tree House B&B

Cottage Tree House B&B

Hopkins SC
At this vacation home, guests have access to features like laundry facilities. This family-friendly vacation home also has barbecue grills.
Summervielle Beautiful House

Summervielle Beautiful House

Summerville SC
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.
Don't see what you're looking for?
See all available properties in Orangeburg County
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Orangeburg County

    Tru By Hilton Santee

    Tru By Hilton Santee

    263 Britain St. and 273 Britain St. Santee SC
    $112 nightly
    The price is $124 total per night from Mar 16 to Mar 17
    $124 total
    Mar 16 - Mar 17
    Total with taxes and fees
    9.2/10 Wonderful! (750 reviews)
    Tru by Hilton Orangeburg

    Tru by Hilton Orangeburg

    739 Citadel Road Orangeburg SC
    $114 nightly
    The price is $127 total per night from Mar 24 to Mar 25
    $127 total
    Mar 24 - Mar 25
    Total with taxes and fees
    9.2/10 Wonderful! (1,002 reviews)
    Baymont by Wyndham Santee

    Baymont by Wyndham Santee

    249 Britain Street Santee SC
    $80 nightly
    The price is $89 total per night from Mar 8 to Mar 9
    $89 total
    Mar 8 - Mar 9
    Total with taxes and fees
    8/10 Very Good! (1,440 reviews)

Orbitz makes it easy to find vacation rentals in Orangeburg County 

🏠 What is the best price for a Orangeburg County vacation rental?


Orangeburg County rentals range between $89 and $505 per night. At Orbitz, we have a vacation rental for every budget.


🏠 What types of vacation rentals in Orangeburg County can I rent?


Choose from apartments to beautifully decorated vacation homes, condo resorts or even B&Bs or motels for your next Orangeburg County getaway. Orbitz filters your search results so you can find the best Orangeburg County vacation rental for you. We have tons of options.


🏠 Are cancellations free on Orangeburg County vacation rentals with Orbitz?


You may be able to cancel or amend your Orangeburg County vacation rental booking free of charge before a pre-agreed deadline. Make sure to check the terms of cancellation before you book—so you know exactly where you stand. 


🏠 How do I find the best vacation rental deals in Orangeburg County?


Enter your travel dates, and we’ll do the rest. You can then browse our exciting deals and all the tempting vacation rentals we have on offer in Orangeburg County by filtering your search by amenities, prices, and property types and look at customers ratings to help you pick.


🏠 How do I cancel my vacation rental booking through Orbitz


Vacation rentals have slightly different rules to other bookings on Orbitz. Usually, you need to contact your property manager, you may be able to get a full refund before the cancellation date. Click My TripsOpens in a new window on your Orbitz account page to find the right information contact. If you need more help, visit our Customer ServiceOpens in a new window page. 


🏠 What are the advantages of booking a vacation rental in Orangeburg County?


When you book a Orangeburg County vacation rental, you have the privacy of home and can add on those luxury amenities of a hotel. Filter your vacation rental results to find a place with a hot tub or pool, games rooms or large patio with a barbecue. With so much choice on offer, it’s easy to plan the perfect trip with Orbitz. 


🏠 Where can I find vacation rentals in Orangeburg County?


Escape back to nature and check out some of the smaller towns. You’ll find great vacation rentals right across Orangeburg County—with plenty of hidden gems. We also have plenty of inventory in Orangeburg County main cities and near popular attraction spots.


🏠 Why should I book my Orangeburg County vacation rental with Orbitz?


At Orbitz, we search the market for the best accommodation, flights, and car rental deals, so you don’t have to. We’ll help you build your dream Orangeburg County vacation. With plenty of vacation rentals on offer, you can be sure to find the one that’s right for you in just a few clicks. 


More to Explore