Hotels with Restaurants in Orangeburg
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Featured Orangeburg Hotels with Restaurants

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $131 total per night
$131 total
Dec 21 - Dec 22
Total with taxes and fees
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.
Pool
Breakfast included

Spark by Hilton Orangeburg
731 Citadel Road Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $97 total per night
$97 total
Dec 16 - Dec 17
Total with taxes and fees
Renovated in 2025, Spark by Hilton Orangeburg offers a gym, free WiFi in public areas, and a seasonal outdoor pool. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, express check-out, and a terrace.
Pool
Breakfast included

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$55 nightly
The price is $61 total per night
$61 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Baymont by Wyndham Orangeburg North enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this adults-only hotel include coffee/tea in a common area, express check-out, and laundry facilities.
Pool
Breakfast included

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$112 nightly
The price is $124 total per night
$124 total
Dec 23 - Dec 24
Total with taxes and fees
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.
Pool
Breakfast included

Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
Free Cancellation
$104 nightly
The price is $115 total per night
$115 total
Dec 15 - Dec 16
Total with taxes and fees
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.
Pool
Pet friendly

Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $78 total per night
$78 total
Dec 14 - Dec 15
Total with taxes and fees
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a vending machine.
Breakfast included
Pet friendly

Hampton Inn & Suites Orangeburg
749 Citadel Road Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $123 total per night
$123 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Hampton Inn & Suites Orangeburg have access to an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and express check-in.
Pool
Breakfast included

Travelodge by Wyndham Orangeburg
3620 Saint Matthews Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $88 total per night
$88 total
Dec 14 - Dec 15
Total with taxes and fees
Travelodge by Wyndham Orangeburg features free WiFi in public areas, coffee in a common area, and express check-out. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests. This smoke-free motel also has a vending machine.
Parking included
Free WiFi

Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $114 total per night
$114 total
Dec 21 - Dec 22
Total with taxes and fees
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Baymont by Wyndham Santee
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $79 total per night
$79 total
Dec 14 - Dec 15
Total with taxes and fees
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.
Breakfast included
Pet friendly

Comfort Inn & Suites Orangeburg
746 Citadel Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $105 total per night
$105 total
Dec 21 - Dec 22
Total with taxes and fees
At Comfort Inn & Suites Orangeburg, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and tours or tickets. Additional amenities include a business center, a meeting room, and express check-out.
Pool
Breakfast included

Days Inn by Wyndham Orangeburg
3691 Saint Matthews Rd Orangeburg SC
Free Cancellation
Reserve now, pay when you stay
$43 nightly
The price is $48 total per night
$48 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Days Inn by Wyndham Orangeburg enjoy free WiFi in public areas, a business center, and express check-out. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities and a vending machine.
Breakfast included
Pet friendly

Super 8 by Wyndham Santee
9125 Old Highway 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $78 total per night
$78 total
Dec 14 - Dec 15
Total with taxes and fees
Guests of Super 8 by Wyndham Santee enjoy access to free WiFi in public areas, meeting rooms, and a business center. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Other amenities at this golf motel include a seasonal outdoor pool, express check-in, and express check-out.
Pool
Breakfast included

Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $68 total per night
$68 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Travelodge by Wyndham Santee features free WiFi in public areas, a business center, and coffee in a common area. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and tours/tickets. Additional amenities include an ATM and a vending machine.
Breakfast included
Pet friendly

Holiday Inn Express & Suites Orangeburg by IHG
118 Sleep Inn Road Orangeburg SC
Free Cancellation
$114 nightly
The price is $127 total per night
$127 total
Dec 21 - Dec 22
Total with taxes and fees
At Holiday Inn Express & Suites Orangeburg by IHG, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and express check-out.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Orangeburg hotels essential information
Accommodation | 256 hotels |
|---|---|
Lowest Price | $48 |
Highest Price | $131 |
Popular hotels | Best Western Plus Santee Inn, Spark by Hilton Orangeburg, Baymont by Wyndham Orangeburg North, Hampton Inn Santee-I-95, Holiday Inn Santee by IHG, Red Roof Inn Santee, Hampton Inn & Suites Orangeburg, Travelodge by Wyndham Orangeburg, Comfort Inn & Suites Santee, Baymont by Wyndham Santee, Comfort Inn & Suites Orangeburg, Days Inn by Wyndham Orangeburg, Super 8 by Wyndham Santee, Travelodge by Wyndham Santee, Holiday Inn Express & Suites Orangeburg by IHG |
Recent Hotels with Restaurants Reviews

Comfort Inn & Suites Orangeburg
5/5 Excellent
"STAFF"
A verified traveler stayed at Comfort Inn & Suites Orangeburg
Posted 3 days ago
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