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Top Orangeburg County hotels

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $144 total per night from Jun 8 to Jun 9
$144 total
Jun 8 - Jun 9
Total includes taxes and fees
Guests staying at Fairfield Inn & Suites by Marriott Santee enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use ...
9.8/10 Exceptional! (1,002 reviews)
"Property was a convenient location for our trip south."

Reviewed on May 29, 2025

Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $151 total per night from Jun 9 to Jun 10
$151 total
Jun 9 - Jun 10
Total includes taxes and fees
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. ...
9.4/10 Exceptional! (1,001 reviews)
"CLEAN"

Reviewed on May 28, 2025

Hampton Inn Santee-I-95
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from Jun 8 to Jun 9
$122 total
Jun 8 - Jun 9
Total includes taxes and fees
At Tru By Hilton Santee, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front ...
9/10 Wonderful! (433 reviews)
"Easy access to 95 highway and many food restaurants."

Reviewed on May 30, 2025

Tru By Hilton Santee
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 out of 5
739 Citadel Road, Orangeburg, SC
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $146 total per night from Jun 30 to Jul 1
$146 total
Jun 30 - Jul 1
Total includes taxes and fees
At Tru by Hilton Orangeburg, guests have access to a gym, free WiFi in public areas, and a business center. Free parking is available if you drive. The 24-hour ...
9/10 Wonderful! (1,000 reviews)
"Clean and quiet property"

Reviewed on May 17, 2025

Tru by Hilton Orangeburg
Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG

2.5 out of 5
118 Sleep Inn Road, Orangeburg, SC
Fully refundable
$110 nightly
The price is $122 total per night from Jun 8 to Jun 9
$122 total
Jun 8 - Jun 9
Total includes taxes and fees
At Holiday Inn Express & Suites Orangeburg by IHG, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. If you drive, ...
8.4/10 Very Good! (743 reviews)
"Excellent hotel. Great staff and super clean all the way around. Would recommend for anyone in the area"

Reviewed on May 25, 2025

Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
Fully refundable
$127 nightly
The price is $141 total per night from Jul 2 to Jul 3
$141 total
Jul 2 - Jul 3
Total includes taxes and fees
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk ...
8/10 Very Good! (887 reviews)
"It was a good stay with friendly and helpful staff! My only complaint was the hallways smelled like per urine."

Reviewed on May 20, 2025

Holiday Inn Santee by IHG
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from Jun 8 to Jun 9
$122 total
Jun 8 - Jun 9
Total includes taxes and fees
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. ...
8/10 Very Good! (993 reviews)
Convenient and Friendly Staff
"Conveniently located off I-95. The staff were all very friendly. The rooms were very spacious. The breakfast was great! The only downside was the beds need updated. They were very springy and uncomfortable. Overall good stay."

Reviewed on May 28, 2025

Comfort Inn & Suites Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Jun 2 to Jun 3
$89 total
Jun 2 - Jun 3
Total includes taxes and fees
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good ...
7.8/10 Good! (1,302 reviews)
"Great place to break up the trip to Mrytle beach"

Reviewed on May 27, 2025

Baymont by Wyndham Santee
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

2 out of 5
3608 Saint Matthews Rd, Orangeburg, SC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $59 total per night from Jun 8 to Jun 9
$59 total
Jun 8 - Jun 9
Total includes taxes and fees
Super 8 by Wyndham, Orangeburg features free WiFi in public areas, a business center, and coffee in a common area. If you drive, put free parking to good use. ...
6.6/10 (803 reviews)
"Love it"

Reviewed on May 20, 2025

Super 8 by Wyndham, Orangeburg
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Jun 8 to Jun 9
$67 total
Jun 8 - Jun 9
Total includes taxes and fees
Quality Inn & Suites features free WiFi in public areas, a seasonal outdoor pool, and microwave in a common area. If you drive, put free parking to good use. ...
5.8/10 (382 reviews)
"Very friendly and helpful staff . Older property but very clean and the bed was comfy . Breakfast was very nice"

Reviewed on May 24, 2025

Quality Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cities in Orangeburg County

Orangeburg County Hotels

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