Hotels near Santee National Wildlife Refuge
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Check prices close to Santee National Wildlife Refuge for tonight, Nov 3 - Nov 4Tomorrow night
Check prices close to Santee National Wildlife Refuge for tomorrow night, Nov 4 - Nov 5Featured Hotels near Santee National Wildlife Refuge

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly.
Summerton SC
2.27 mi from Santee National Wildlife Refuge
The price is $157 total per night
$157 total
per night
Nov 16 - Nov 17
This cabin is a smoke-free cabin.
Kitchen
Pet friendly

Sunset Serenity, Lake Marions Ultimate Dream Getaway Pool/swimspa/sleeps 16
Summerton SC
2.56 mi from Santee National Wildlife Refuge
Guests staying at this vacation home enjoy a hot tub, laundry facilities, and barbecue grills. This smoke-free vacation home also has a garden.
Pool
Hot Tub

Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway.
Summerton SC
2.78 mi from Santee National Wildlife Refuge
The price is $271 total per night
$271 total
per night
Nov 16 - Nov 17
At this cabin, guests have access to features like laundry facilities. This smoke-free cabin also has a garden.
Kitchen
Washer

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
The price is $137 total per night
$137 total
per night
Nov 25 - Nov 26
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.
Pool
Breakfast included

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
The price is $132 total per night
$132 total
per night
Nov 22 - Nov 23
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
The price is $154 total per night
$154 total
per night
Nov 15 - Nov 16
Guests staying at Fairfield Inn & Suites by Marriott Santee enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, luggage storage, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Breakfast included

Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
4.46 mi from Santee National Wildlife Refuge
The price is $111 total per night
$111 total
per night
Nov 22 - Nov 23
At Tru By Hilton Santee, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. This hotel also has a 24-hour business center.
Pool
Breakfast included

Baymont by Wyndham Santee
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
4.48 mi from Santee National Wildlife Refuge
The price is $89 total per night
$89 total
per night
Nov 4 - Nov 5
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.
Breakfast included
Pet friendly

Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
4.49 mi from Santee National Wildlife Refuge
The price is $110 total per night
$110 total
per night
Nov 29 - Nov 30
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
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See all available properties in Santee National Wildlife Refuge
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santee National Wildlife Refuge hotels essential information
Accommodation | 435 hotels |
|---|---|
Lowest Price | $89 |
Highest Price | $271 |
Popular hotels | Tru By Hilton Santee, Baymont by Wyndham Santee, Fairfield Inn & Suites by Marriott Santee, Lakefront tiny cabin amazing view on Lake Marion! Pet friendly., Best Western Plus Santee Inn, Sunset Serenity, Lake Marions Ultimate Dream Getaway Pool/swimspa/sleeps 16, Hampton Inn Santee-I-95, Comfort Inn & Suites Santee, Relax and unwind near Lake Marion - 2-bedroom 1.5 bath cabin getaway. |
Recent Reviews

Baymont by Wyndham Santee
5/5 Excellent
"Great location very clean"
A verified traveler stayed at Baymont by Wyndham Santee
Posted 3 hours ago
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