Hotels in Santee

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Top Rated Santee Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santee attractions

Cheap Santee hotels options

    Baymont by Wyndham Santee

    Baymont by Wyndham Santee

    249 Britain Street Santee SC
    $80 nightly
    The price is $89 total per night from Nov 10 to Nov 11
    $89 total
    Nov 10 - Nov 11
    Total with taxes and fees
    Red Roof Inn Santee

    Red Roof Inn Santee

    9091 Old Hwy 6 Santee SC
    $63 nightly
    The price is $70 total per night from Nov 12 to Nov 13
    $70 total
    Nov 12 - Nov 13
    Total with taxes and fees
    Travelodge by Wyndham Santee

    Travelodge by Wyndham Santee

    9117 Old Number Six Hwy Santee SC
    $64 nightly
    The price is $71 total per night from Nov 10 to Nov 11
    $71 total
    Nov 10 - Nov 11
    Total with taxes and fees
    7.2/10 Good! (787 reviews)
    Super 8 by Wyndham Santee/I-95

    Super 8 by Wyndham Santee/I-95

    9125 Old Highway 6 Santee SC
    $64 nightly
    The price is $71 total per night from Nov 15 to Nov 16
    $71 total
    Nov 15 - Nov 16
    Total with taxes and fees
    Econo Lodge Santee

    Econo Lodge Santee

    9112 Old 6 Highway Santee SC
    $63 nightly
    The price is $70 total per night from Dec 7 to Dec 8
    $70 total
    Dec 7 - Dec 8
    Total with taxes and fees
    6.4/10 (317 reviews)
    Comfort Inn & Suites Santee

    Comfort Inn & Suites Santee

    221 Britain St Santee SC
    $102 nightly
    The price is $113 total per night from Nov 29 to Nov 30
    $113 total
    Nov 29 - Nov 30
    Total with taxes and fees
    8/10 Very Good! (1,000 reviews)

Where is a good place to stay in Santee?

What are the best family-friendly hotels in Santee?

Check out these hotels for your family's stay in Santee. Fairfield Inn & Suites by Marriott Santee is a hotel offering an outdoor pool, free parking, and free breakfast. You and your family can also consider Comfort Inn & Suites Santee, a hotel offering free parking, free buffet breakfast, and laundry facilities.

What are the best hotels in central Santee?

Here are some of the most popular hotels in the center of Santee:

While you're enjoying local activities like golfing, take some time to check out the restaurants in family-friendly Santee. Close to central Santee, you'll find interesting places to visit like Santee Cooper Country Club.

What are some of the best hotels near Santee State Park?

Get some fresh air at this natural setting, which is 2.7 mi from the heart of Santee. You'll find 20 hotels within 5 miles of Santee State Park, giving you plenty of options to choose from including:

Santee hotels essential information

Accommodation
353 hotels
Lowest Price
$65
Highest Price
$154
Popular hotels
Tru By Hilton Santee, Baymont by Wyndham Santee, Fairfield Inn & Suites by Marriott Santee, Comfort Inn & Suites Santee, Best Western Plus Santee Inn, Hampton Inn Santee-I-95, Holiday Inn Santee by IHG, Quality Inn & Suites Santee I-95, Travelodge by Wyndham Santee, Ramada by Wyndham Santee I-95, CatDaddy Cabin - Lake Marion Cabin in Santee - lake view, fire pit, boat parking, Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

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