Hotels in Santee

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Sep 25 - Sep 26
Tonight
Check prices in Santee for tonight, Sep 25 - Sep 26
Sep 26 - Sep 27
Tomorrow night
Check prices in Santee for tomorrow night, Sep 26 - Sep 27

Top Rated Santee Hotels

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.26 mi from city center
$112 nightly
The price is $124 total per night
$124 total
Sep 28 - Sep 29
Total with taxes and fees
At Tru By Hilton Santee, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. This hotel also has a 24-hour business center.
Pool
Breakfast included
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.26 mi from city center
$75 nightly
The price is $83 total per night
$83 total
Sep 28 - Sep 29
Total with taxes and fees
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.
Breakfast included
Pet friendly
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.62 mi from city center
$125 nightly
The price is $139 total per night
$139 total
Oct 1 - Oct 2
Total with taxes and fees
Guests staying at Fairfield Inn & Suites by Marriott Santee enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Breakfast included
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
0.59 mi from city center
$140 nightly
The price is $156 total per night
$156 total
Oct 6 - Oct 7
Total with taxes and fees
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.
Pool
Breakfast included
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
Free Cancellation
0.17 mi from city center
$127 nightly
The price is $141 total per night
$141 total
Oct 26 - Oct 27
Total with taxes and fees
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.
Pool
Pet friendly
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.17 mi from city center
$107 nightly
The price is $119 total per night
$119 total
Sep 28 - Sep 29
Total with taxes and fees
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.14 mi from city center
$64 nightly
The price is $71 total per night
$71 total
Oct 1 - Oct 2
Total with taxes and fees
Quality Inn & Suites features free WiFi in public areas, a seasonal outdoor pool, and microwave in a common area. If you drive, put free parking to good use. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include a refrigerator in a common area, a computer station, and laundry facilities.
Pool
Breakfast included
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.56 mi from city center
$114 nightly
The price is $126 total per night
$126 total
Oct 6 - Oct 7
Total with taxes and fees
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.
Pool
Breakfast included
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.73 mi from city center
$62 nightly
The price is $69 total per night
$69 total
Sep 28 - Sep 29
Total with taxes and fees
Travelodge by Wyndham Santee features free WiFi in public areas, a business center, and coffee in a common area. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with tours/tickets and securing valuables. Additional amenities include a vending machine and an ATM.
Breakfast included
Pet friendly
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.17 mi from city center
$73 nightly
The price is $81 total per night
$81 total
Sep 28 - Sep 29
Total with taxes and fees
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a vending machine.
Breakfast included
Pet friendly
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.45 mi from city center
$72 nightly
The price is $80 total per night
$80 total
Sep 28 - Sep 29
Total with taxes and fees
Guests of Ramada by Wyndham Santee I-95 have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking, and an airport shuttle (available 24 hours) for USD 80 per room roundtrip. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include meeting rooms, a conference center, and a 24-hour business center.
Pool
Breakfast included
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive, Santee, SC
0.16 mi from city center
Guests staying at Wyndham Vacation Resorts Lake Marion enjoy features like an outdoor pool. Free parking is included with your stay.
Pool
Kitchen
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Santee hotels options

    Baymont by Wyndham Santee

    Baymont by Wyndham Santee

    249 Britain Street, Santee, SC
    $75 nightly
    The price is $83 total per night from Sep 28 to Sep 29
    $83 total
    Sep 28 - Sep 29
    Total with taxes and fees
    7.8/10 Good! (1,348 reviews)
    Red Roof Inn Santee

    Red Roof Inn Santee

    9091 Old Hwy 6, Santee, SC
    $73 nightly
    The price is $81 total per night from Sep 28 to Sep 29
    $81 total
    Sep 28 - Sep 29
    Total with taxes and fees
    6.4/10 (625 reviews)
    Travelodge by Wyndham Santee

    Travelodge by Wyndham Santee

    9117 Old Number Six Hwy, Santee, SC
    $62 nightly
    The price is $69 total per night from Sep 28 to Sep 29
    $69 total
    Sep 28 - Sep 29
    Total with taxes and fees
    7/10 Good! (656 reviews)
    Super 8 by Wyndham Santee

    Super 8 by Wyndham Santee

    9125 Old Highway 6, Santee, SC
    $75 nightly
    The price is $83 total per night from Sep 28 to Sep 29
    $83 total
    Sep 28 - Sep 29
    Total with taxes and fees
    6.6/10 (433 reviews)
    Econo Lodge

    Econo Lodge

    9112 Old 6 Highway, Santee, SC
    $61 nightly
    The price is $68 total per night from Oct 26 to Oct 27
    $68 total
    Oct 26 - Oct 27
    Total with taxes and fees
    6.2/10 (308 reviews)
    Comfort Inn & Suites Santee

    Comfort Inn & Suites Santee

    221 Britain St, Santee, SC
    $107 nightly
    The price is $119 total per night from Sep 28 to Sep 29
    $119 total
    Sep 28 - Sep 29
    Total with taxes and fees
    7.8/10 Good! (1,004 reviews)

Where is a good place to stay in Santee?

What are the best family-friendly hotels in Santee?

Check out these hotels for your family's stay in Santee. Fairfield Inn & Suites by Marriott Santee is a hotel offering an outdoor pool, free parking, and free breakfast. You and your family can also consider Comfort Inn & Suites Santee, a hotel offering free parking, free buffet breakfast, and laundry facilities.

What are the best hotels in central Santee?

Here are some of the most popular hotels in the center of Santee:

While you're enjoying local activities like golfing, take some time to check out the restaurants in family-friendly Santee. Santee Cooper Country Club and Santee National Golf Club are a couple of sights to visit in the heart of Santee.

What are some of the best hotels near Santee State Park?

Get some fresh air at this natural setting, which is 2.7 mi from the heart of Santee. You'll find 20 hotels within 5 miles of Santee State Park, giving you plenty of options to choose from including:

Santee hotels essential information

Accommodation
288 hotels
Lowest Price
$68
Highest Price
$156
Popular hotels
Tru By Hilton Santee, Baymont by Wyndham Santee, Fairfield Inn & Suites by Marriott Santee, Hampton Inn Santee-I-95, Holiday Inn Santee by IHG, Comfort Inn & Suites Santee, Quality Inn & Suites, Best Western Plus Santee Inn, Travelodge by Wyndham Santee, Red Roof Inn Santee, Ramada by Wyndham Santee I-95, Wyndham Vacation Resorts Lake Marion

Recent Reviews

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

5/5 Excellent
"The desk clerk was very friendly"
A verified traveler from Alexandria stayed at Hampton Inn Santee-I-95
Posted 3 days ago
Hampton Inn Santee-I-95

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