$168 Cheap flight deals from Houston (HOU) to Santee (CAE)
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This Weekend's Flight Deals from Houston to Santee
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $168 One Way, $295 Round Trip from Houston to Santee
Prices starting at $295 for return flights and $168 for one-way flights to Santee were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santee economy flight packages
Hilton Garden Inn Columbia Downtown, SC
Mar 26 - Mar 31
Houston (HOU) to Columbia (CAE)
Reviewed on Dec 13, 2025
Graduate by Hilton Columbia SC
Mar 26 - Mar 31
Houston (HOU) to Columbia (CAE)
Reviewed on Jul 29, 2025
Hyatt Place Columbia/Downtown/The Vista
Mar 26 - Mar 31
Houston (HOU) to Columbia (CAE)
Reviewed on Oct 19, 2025
More About Flying To Santee from Houston
Route Information for Flights from Houston to Santee
Origin Airport IATA Code | HOU |
|---|---|
Destination Airport IATA Code | CAE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Houston to Santee
Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from Houston to Santee to give you a travel experience that is second to none.
Bargain Travel at Your Fingertips
Orbitz provides the cheapest fares from Houston to Santee. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.
Modern Tools for Fast-Paced Travel
Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your Houston to Santee flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from Houston to Santee and choose a range of cheap hotels to stay in.
Enjoy Stress-Free Travel with Flight Alerts
Once you have booked your flights from Houston to Santee on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your Houston to Santee flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.
Frequent Flyer Program
For loyal Orbitz customers who fly from Houston to Santee the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.
Flights from Houston
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Santee Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.