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Top Rated Mississippi County Hotels

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Free Cancellation
Reserve now, pay when you stay
$62 nightly
The price is $69 total per night
$69 total
Mar 23 - Mar 24
Total with taxes and fees
At Super 8 by Wyndham Charleston/Sikeston East MO, guests have access to free WiFi in public areas, a business center, and a computer station. A stay here includes free parking. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Additional amenities include laundry facilities, a TV in a common area, and a vending machine.

The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $78 total per night
$78 total
Mar 23 - Mar 24
Total with taxes and fees
Guests of The Riverstone Hotel Charleston-Sikeston enjoy free WiFi in public areas, a business center, and a vending machine. A stay here includes free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $108 total per night
$108 total
Mar 26 - Mar 27
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$97 nightly
The price is $110 total per night
$110 total
Apr 12 - Apr 13
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include meeting rooms, conference space, and a 24-hour business center.

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $106 total per night
$106 total
Mar 29 - Mar 30
Total with taxes and fees
Guests of Best Western Plus Sikeston I-55 have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $75 total per night
$75 total
Mar 23 - Mar 24
Total with taxes and fees
Guests of Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.

Sleep Inn at Discovery Park of America
1111 BLue Heron Lane Union City TN
Free Cancellation
$76 nightly
The price is $90 total per night
$90 total
Apr 5 - Apr 6
Total with taxes and fees
At Sleep Inn at Discovery Park of America, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a meeting room.

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $78 total per night
$78 total
Mar 25 - Mar 26
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mississippi County hotels essential information
Accommodation | 105 hotels |
|---|---|
Lowest Price | $69 |
Highest Price | $179 |
Popular hotels | Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston, Drury Inn & Suites Sikeston, MO, Hampton Inn Sikeston, Best Western Plus Sikeston I-55, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67), Sleep Inn at Discovery Park of America, Days Inn and Suites by Wyndham Sikeston, Great location just across the street from Reelfoot Lake close to boat ramps |
Recent Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
5/5 Excellent
"Very nice place, very nice stay! They were out of cream cheese for the bagels at breakfast though.:-)"
A verified traveler stayed at Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Posted 3 hours ago
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