Compare Hotels in Mississippi County
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Top cities in Mississippi County
Top Rated Mississippi County Hotels

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $66 total per night
$66 total
Jun 14 - Jun 15
Total with taxes and fees
At Super 8 by Wyndham Charleston/Sikeston East MO, guests have access to free WiFi in public areas, a business center, and a computer station. A stay here includes free parking. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Additional amenities include laundry facilities, a vending machine, and a TV in a common area.
Breakfast included
Pet friendly

The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Jun 14 - Jun 15
Total with taxes and fees
Guests of The Riverstone Hotel Charleston-Sikeston enjoy access to free WiFi in public areas, a 24-hour business center, and a seasonal outdoor pool. A stay here includes free parking. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include coffee/tea in a common area and a vending machine.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $128 total per night
$128 total
Jun 21 - Jun 22
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $79 total per night
$79 total
Jun 16 - Jun 17
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a banquet hall.
Breakfast included
Pet friendly

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $115 total per night
$115 total
Jul 12 - Jul 13
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Peaceful secluded cabin located near Horseshoe Lake
Miller City IL
$175 nightly
The price is $185 total per night
$185 total
Jun 14 - Jun 15
Total with taxes and fees
At this cabin, guests have access to barbecue grills.
Kitchen
Pet friendly

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $99 total per night
$99 total
Jul 14 - Jul 15
Total with taxes and fees
Guests of Best Western Plus Sikeston I-55 have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $78 total per night
$78 total
Jun 21 - Jun 22
Total with taxes and fees
Guests staying at Super 8 by Wyndham Sikeston/Miner Area enjoy free WiFi in public areas, a library, and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Breakfast included
Pet friendly

Sleep Inn at Discovery Park of America
1111 BLue Heron Lane Union City TN
Free Cancellation
$79 nightly
The price is $94 total per night
$94 total
Jul 12 - Jul 13
Total with taxes and fees
At Sleep Inn at Discovery Park of America, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a meeting room.
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See all available properties in Mississippi County
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mississippi County hotels essential information
Accommodation | 111 hotels |
|---|---|
Lowest Price | $66 |
Highest Price | $185 |
Popular hotels | Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston, Drury Inn & Suites Sikeston, MO, Days Inn and Suites by Wyndham Sikeston, Hampton Inn Sikeston, Peaceful secluded cabin located near Horseshoe Lake , Best Western Plus Sikeston I-55, Super 8 by Wyndham Sikeston/Miner Area, Sleep Inn at Discovery Park of America |
Recent Reviews

Drury Inn & Suites Sikeston, MO
5/5 Excellent
"Evening drinks and meal were included. Breakfast was also included and very good"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Posted 1 day ago
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