$170 Cheap flights to Distrito Colón
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Top places to visit in Distrito Colón
Cheap flights to Distrito Colón from $170 One Way, $248 Round Trip
$248 return flights and $170 one-way flights to Distrito Colón were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| SJO | Tocumen | November 7 to November 14 | $283 |
| CCS | Tocumen | November 6 to November 9 | $529 |
| MIA | Tocumen | November 6 to November 8 | $612 |
| FLL | Tocumen | November 7 to November 18 | $630 |
| ATL | Tocumen | November 7 to November 18 | $712 |
| MEX | Tocumen | November 6 to November 13 | $718 |
| JFK | Tocumen | November 6 to November 9 | $788 |
| JFK | Tocumen | November 6 to November 9 | $788 |
| LAX | Tocumen | November 6 to November 13 | $899 |
Find The Perfect Hotel For After Your Flight
Score Epic Distrito Colón Accommodation Deals
Hotel Riu Plaza Panama
"The hotel is very well located, and the breakfast is decent. However, our room had a strong mildew smell and seemed poorly ventilated. The air conditioning appeared to have been left off before our arrival. Although it was turned on as soon as we arrived, the unpleasant smell persisted and kept me ..."
Reviewed on Nov 2, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
"Clean room."
Reviewed on Nov 2, 2026
Megapolis Hotel Panamá
"Excellent"
Reviewed on Nov 2, 2026
Crowne Plaza Panama Airport by IHG
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
Distrito Colón
Are you in the mood for a cruise? Shop Orbitz today for cheap cruises and flights to Distrito Colón. Our award-winning cruise site features exclusive offers, information for first-timers and top destinations and activities. Make discount domestic and international travel plans in an instant with cutting-edge mobile tools from Orbitz.
Top Pick
Orbitz holds a “Best of the Web” Cruise Site Award from Forbes Magazine. You won’t find better deals anywhere on low cost cruises and low fare Distrito Colón flights. Our Customer Care and guaranteed low prices make Orbitz the team to beat in budget cruises and air ticket sales.
Exclusive Offers
Register for Orbitz email updates and our cruise experts will notify you of bargain tickets on cruises as they’re posted. Install our free mobile apps on your iPad, iPhone or Android for easy booking and mobile-only savings on flights to Distrito Colón. Visit www.Orbitz.com to learn more about these amazing benefits and our 110% Best Price Guarantee.
First-Timers
Are you and your family cruise newbies? Orbitz offers Cruising 101 and Cruise FAQ to answer any questions you may have. Book your cruise and air travel with Orbitz On the Go for greater savings on Distrito Colón flights.
Ports and Play
Be sure to check our cruise page for free shore excursions, onboard spending, balcony upgrades and other perks. Orbitz offers last-minute, luxury, weekend and summer cruises. You can even designate which port you want to sail from and pre-book on-shore activities. Get there on the cheap with discounts on flights to Distrito Colón and Distrito Colón flights. Get more bang for your travel buck at Orbitz.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.