Depew, NY Vacation Packages

Book a Stay + Flight or Car to save on your Vacation Package

Choose two or more items and save on your trip:

Depew Vacation Packages

Just kick back, take it easy and let the travel specialists at Orbitz help you craft an amazing Depew escape. If you want to bundle your hotels and flights to save money and stress, you're on the right track!

You have the opportunity to save up to when you combine your bookings. All you have to do is select your desired airfares, hotels, experiences and rental cars.

With 500 partner airlines to pick from, you'll be fastening your seat-belt and preparing for take off in no time! And if you're wondering where to stay, we've got an extensive database of more than 500,000 accommodations across the globe.

When it comes to tailoring the vacation of your dreams, your options are limitless with Orbitz.

Where is Depew?

Venturing to someplace new is exciting — and somewhat daunting too. Take some of the worries out of your journey by researching Depew, starting with its location.

It's a neighborhood in the fantastic city of Buffalo. You'll find it located 9 miles to the east of the downtown area.

Ready to rub shoulders with the locals? 260,000 people reside in Buffalo.

Car Rentals in Depew

Want to see the region on your own terms? Be the architect of your own epic adventure by checking out car rentals in Depew with the help of Orbitz.After you disembark your flight, head on over to collect a vehicle from Buffalo Niagara International Airport. Budget and Avis are some trusty options here. Other places to investigate are Hertz and Alamo Rent A Car.Hertz is conveniently positioned in the heart of the city at 4800 Broadway. If you plan to stay nearby, this is a great place to go.

Where to stay in Depew – Hotel Accommodation

Let Orbitz help you secure an unbelievable deal! Currently, there are 49 hotels in Depew — pick one that suits your very own style.

Want us to make things easier? We recommend the Homewood Suites by Hilton Buffalo Airport and Residence Inn by Marriott Buffalo Galleria Mall.

Nearest Airports to Depew

Your adventure starts the moment you step out of the cabin at Buffalo Niagara International Airport (BUF). Situated 2 miles northwest of Depew, it's the neighborhood's main terminal.

Popular Places to Visit Near Depew

Cheektowaga and Buffalo Niagara International Airport are well worth visiting while you are in Depew. Cheektowaga is around 3 miles away, while Buffalo Niagara International Airport is 3 miles away.

No Cancellation Fees

Breathe easy knowing that whatever the motivation behind amending or canceling your booking, we won't charge you a fee.^ Why not touch base with your selected hotel and airline to check if they do the same?

Top rated hotels for your Depew vacation package

Don't see what you're looking for?
See all available properties in Depew
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More trip options