Book 5 Star Hotels in Greenville

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Featured Greenville 5 Stars Hotels

Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG

3 out of 5
930 Crosswind Street, Greenville, NC
Free Cancellation
1.54 mi from city center
$95 nightly
The price is $107 total per night
$107 total
Oct 26 - Oct 27
Total with taxes and fees
Staybridge Suites Greenville Medical Center by IHG features free WiFi in public areas, a computer station, and laundry facilities. Free parking is included with your stay. Helpful staff can provide luggage storage, a safe deposit box at the front desk, and access to locker space. Additional amenities include a convenience store, a water dispenser, and a TV in a common area.
Breakfast included
Parking included
Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic

2 out of 5
450 Moye Blvd, Greenville, NC
Free Cancellation
Reserve now, pay when you stay
1.65 mi from city center
$72 nightly
The price is $82 total per night
$82 total
Oct 7 - Oct 8
Total with taxes and fees
At Microtel Inn & Suites by Wyndham Greenville/University Medic, guests have access to a 24-hour gym, free WiFi in public areas, and a conference center. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, laundry facilities, and a TV in a common area.
Breakfast included
Parking included
Comfort Inn & Suites Greenville Near Convention Center

Comfort Inn & Suites Greenville Near Convention Center

2.5 out of 5
3212 S Memorial Dr, Greenville, NC
Free Cancellation
Reserve now, pay when you stay
3.04 mi from city center
$107 nightly
The price is $121 total per night
$121 total
Oct 12 - Oct 13
Total with taxes and fees
At Comfort Inn & Suites Greenville Near Convention Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a business center, express check-out, and a vending machine.
Pool
Breakfast included
Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville

2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
Free Cancellation
Reserve now, pay when you stay
2.34 mi from city center
$109 nightly
The price is $123 total per night
$123 total
Oct 26 - Oct 27
Total with taxes and fees
Guests staying at Best Western Plus Suites-Greenville enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include a 24-hour business center, a meeting room, and free newspapers.
Pool
Breakfast included
Quality Inn Greenville near University

Quality Inn Greenville near University

2.5 out of 5
821 Memorial Dr, Greenville, NC
Free Cancellation
Reserve now, pay when you stay
1.35 mi from city center
$80 nightly
The price is $91 total per night
$91 total
Oct 6 - Oct 7
Total with taxes and fees
Quality Inn Greenville near University features a gym, free WiFi in public areas, and a seasonal outdoor pool. Free parking is included with your stay. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include coffee/tea in a common area, free newspapers, and laundry facilities.
Pool
Breakfast included
Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG

3 out of 5
203 Greenville Blvd SW, Greenville, NC
Free Cancellation
2.76 mi from city center
$111 nightly
The price is $125 total per night
$125 total
Oct 6 - Oct 7
Total with taxes and fees
Guests staying at Holiday Inn Greenville by IHG enjoy a children's pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a conference center, a business center, and a seasonal outdoor pool.
Pool
Parking included
Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG

2.5 out of 5
909 Moye Blvd, Greenville, NC
Free Cancellation
1.55 mi from city center
$99 nightly
The price is $112 total per night
$112 total
Oct 12 - Oct 13
Total with taxes and fees
Guests of Holiday Inn Express Greenville by IHG enjoy a 24-hour gym, free WiFi in public areas, and a business center. There's free parking, as well as a free airport shuttle (available on request). The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Additional amenities include a meeting room, a computer station, and express check-out.
Pool
Breakfast included
Baymont by Wyndham Greenville

Baymont by Wyndham Greenville

2.5 out of 5
3439 S Memorial Drive, Greenville, NC
Free Cancellation
Reserve now, pay when you stay
3.49 mi from city center
$65 nightly
The price is $73 total per night
$73 total
Oct 11 - Oct 12
Total with taxes and fees
Guests of Baymont by Wyndham Greenville have access to an outdoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC

3 out of 5
420 Moye Blvd, Greenville, NC
Free Cancellation
Reserve now, pay when you stay
1.6 mi from city center
$119 nightly
The price is $135 total per night
$135 total
Oct 12 - Oct 13
Total with taxes and fees
Homewood Suites By Hilton Greenville, NC features a 24-hour gym, free WiFi in public areas, and meeting rooms. There's free parking if you drive. The 24-hour front desk has staff always at the ready. Additional amenities include a meeting room, a picnic area, and a banquet hall.
Breakfast included
Pet friendly
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best 5 star hotels in Greenville

Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Greenville. After all, treating yourself to the finer things is what vacations are about. 

What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Greenville hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.

What amenities can I expect at a 5 star hotel?
Greenville 5 star hotels and resorts typically offer luxury amenities such as:

  • Gourmet restaurant
  • Full-service fitness center with pool
  • Luxury spa 
  • Welcome gifts upon arrival
  • Top-of-the-line beds and linens 
  • Designer personal care products
  • Premium cable, free Wi-Fi and device docking stations

How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Greenville with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place: 

  • Search hotels by price, ranging from $73 to $135
  • Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
  • Choose from 247 5 star hotels in Greenville!

Greenville hotels essential information

Accommodation
247 hotels
Lowest Price
$73
Highest Price
$135
Popular hotels
Staybridge Suites Greenville Medical Center by IHG, Microtel Inn & Suites by Wyndham Greenville/University Medic, Comfort Inn & Suites Greenville Near Convention Center, Best Western Plus Suites-Greenville, Quality Inn Greenville near University, Holiday Inn Greenville by IHG, Holiday Inn Express Greenville by IHG, Baymont by Wyndham Greenville, Homewood Suites By Hilton Greenville, NC

Recent Reviews

Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG

5/5 Excellent
"We enjoyed our day. Everything was just perfect."
A verified traveler stayed at Staybridge Suites Greenville Medical Center by IHG
Posted 6 days ago
Staybridge Suites Greenville Medical Center by IHG

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