$281 Cheap flight deals from Quito (UIO) to Santiago (SCL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Quito to Santiago

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Feb 15 - Wed, Feb 25
UIO
Mariscal Sucre Intl.
SCL
Arturo Merino Benitez
$923 Roundtrip, found 4 days ago
$923
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Sun, Feb 15 from Mariscal Sucre Intl. to Arturo Merino Benitez, returning Wed, Feb 25, priced at $923 found 4 days ago

Airfares from $281 One Way, $357 Round Trip from Quito to Santiago

Prices starting at $357 for return flights and $281 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 3 - Sun, Apr 19
UIO
Quito
SCL
Santiago
$357 Roundtrip, found 7 hours ago
$357
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Fri, Apr 3 from Quito to Santiago, returning Sun, Apr 19, priced at $357 found 7 hours ago
Sun, Apr 5 - Sun, Apr 19
UIO
Quito
SCL
Santiago
$393 Roundtrip, found 7 hours ago
$393
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Sun, Apr 5 from Quito to Santiago, returning Sun, Apr 19, priced at $393 found 7 hours ago
Fri, Apr 3 - Fri, Apr 17
UIO
Quito
SCL
Santiago
$401 Roundtrip, found 7 hours ago
$401
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Fri, Apr 3 from Quito to Santiago, returning Fri, Apr 17, priced at $401 found 7 hours ago
Wed, Apr 1 - Sun, Apr 19
UIO
Quito
SCL
Santiago
$402 Roundtrip, found 7 hours ago
$402
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Wed, Apr 1 from Quito to Santiago, returning Sun, Apr 19, priced at $402 found 7 hours ago
Sun, Apr 5 - Fri, Apr 17
UIO
Quito
SCL
Santiago
$437 Roundtrip, found 7 hours ago
$437
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Sun, Apr 5 from Quito to Santiago, returning Fri, Apr 17, priced at $437 found 7 hours ago

More About Flying To Santiago from Quito

Route Information for Flights from Quito to Santiago

Origin Airport IATA Code
UIO
Destination Airport IATA Code
SCL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Quito to Santiago

It has never been easier to find cheap Quito to Santiago flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.

Plan Your Quito to Santiago Flights on the Go

Orbitz offers cutting-edge mobile tools that let you search and book flights anywhere. All you need is a smartphone or mobile device to find discounts on flights from Quito to Santiago. Use the app to check to make sure your flight is on time or book a last-minute cheap hotel room.

Get the Best Deals on Quito to Santiago Flights

Finding great deals on flights from Quito to Santiago is a snap with Orbitz. With our guaranteed low prices, you don’t have to worry if you are getting the best prices on air tickets, hotels, and cruises. And with all that money you saved, you can enjoy your Santiago vacation even more.

Pile Up Miles With Discount Air Tickets

Not only can you find great bargains on Quito to Santiago flights, but you can rack up frequent flyer miles on the flights too. Enter your frequent flyer number on qualified flights when booking for Orbitz to see the miles pile up in your account.

Flight Alerts Keep You Informed

Stay on top of the latest updates for flights from Quito to Santiago. We send you free email and mobile alerts to keep you informed about delays to Quito to Santiago flights.

Frequently asked questions

What is the shortest flight from Quito to Santiago?
With the flight from Quito to Santiago taking a minimum of 3 hours and 9 minutes, there's plenty of time to kick back and enjoy the ride. Order a glass of red and get comfortable in your seat with an engrossing movie or novel.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.