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Fares from $196 One Way, $301 Round Trip from Santa Cruz to Santiago

Prices starting at $301 for return flights and $196 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

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More About Flying To Santiago from Santa Cruz

Santa Cruz to Santiago

When you’re ready to take your next trip, get the most affordable prices on flights from Santa Cruz to Santiago with Orbitz! The guaranteed low prices and cutting-edge mobile tools on Orbits make it easy for you to plan your next great vacation.

Keep Up With Sudden Flight Changes

As any traveler knows, air travel can suddenly be temporarily halted due to service disruptions. Along with offering the best fares for flights from Santa Cruz to Santiago, Orbitz also offers free mobile phone and email alerts that help you keep up with sudden changes to your flight plans. Choose from email, text, or voice message alerts.

Get Great Prices for Santa Cruz to Santiago Flights

Orbitz features both an Android app and an iPhone app to give you the lowest prices for Santa Cruz to Santiago flights. Use these mobile apps to get updates on your flight, the details of your itinerary, and to learn about available hotel deals in the area.

Fly for Less and Earn Miles

Did you know you can earn miles and points for your frequent flyer program with Orbitz? To do this with specific flights from Santa Cruz to Santiago, enter your frequent flyer account number when you book your ticket online. For even more convenience, keep a record of your loyalty travel program numbers directly with Orbitz by storing them in your account profile. This way, you can add your account numbers to your next reservation for Santa Cruz to Santiago flights automatically without the annoying hassle of having to look them up.

Flights from Santa Cruz to Santiago - Frequently Asked Questions

Are there non-stop flights from Santa Cruz to Santiago?

There is. You can fly straight from Santa Cruz to Santiago with LATAM Airlines. It's the only carrier that travels nonstop from Santa Cruz (VVI-Viru Viru Intl.) to Santiago (SCL-Arturo Merino Benitez).

What is the shortest flight from Santa Cruz to Santiago?

Flying from Santa Cruz (VVI-Viru Viru Intl.) to Santiago (SCL-Arturo Merino Benitez) will take a minimum of 3 hours and 3 minutes. Indulge in a tipple and watch a show or two — this is a great opportunity to kick back and unwind.

What airlines fly from Santa Cruz to Santiago (and vicinity) most frequently?

LATAM Airlines is the most frequent flyer along this route. This trusted air carrier operates 13 flights from Santa Cruz to Santiago (and vicinity) every month.

If I am not able to travel due to COVID-19, can I cancel my flight to Santiago?

We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Santiago have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.

Are there flights to Santiago with flexible change policies?

In most cases you'll have the option to reschedule your flight to Santiago without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.

What is the cheapest day of the week to fly?

Consider flying out early in the week to save on your airfare. Orbitz data from 2019 shows that Tuesday is the cheapest day to depart, followed by Monday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.

What is the cheapest month to fly?

We won't keep you guessing, according to Orbitz data the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a fresh start to the new year. Be aware that the most expensive time to fly isn't the height of summer, as most people assume, but the festive month of December.

How can I save money on flights?

To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2019 saved over 50% on their airfares. Get mixing and matching today!

*According to flight demand on Orbitz.com from January to December 2019. Savings are subject to change based on departure location, date and destination.

^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.