$333 Cheap flight deals from Quito (UIO) to Santiago (SCL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Quito to Santiago

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Mar 27 - Fri, Apr 3
UIO
Mariscal Sucre Intl.
SCL
Arturo Merino Benitez
$651 Roundtrip, found 2 days ago
$651
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, Mar 27 from Mariscal Sucre Intl. to Arturo Merino Benitez, returning Fri, Apr 3, priced at $651 found 2 days ago

Airfares from $333 One Way, $585 Round Trip from Quito to Santiago

Prices starting at $585 for return flights and $333 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 22 - Wed, Apr 29
UIO
Quito
SCL
Santiago
$585 Roundtrip, just found
$585
Roundtrip
just found
Select avianca flight, departing Wed, Apr 22 from Quito to Santiago, returning Wed, Apr 29, priced at $585 just found
Tue, Apr 14 - Tue, Apr 28
UIO
Quito
SCL
Santiago
$590 Roundtrip, found 10 hours ago
$590
Roundtrip
found 10 hours ago
Select avianca flight, departing Tue, Apr 14 from Quito to Santiago, returning Tue, Apr 28, priced at $590 found 10 hours ago
Thu, May 7 - Mon, May 11
UIO
Quito
SCL
Santiago
$594 Roundtrip, found 5 days ago
$594
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Thu, May 7 from Quito to Santiago, returning Mon, May 11, priced at $594 found 5 days ago
Wed, Apr 22 - Wed, Apr 29
UIO
Quito
SCL
Santiago
$599 Roundtrip, just found
$599
Roundtrip
just found
Select avianca flight, departing Wed, Apr 22 from Quito to Santiago, returning Wed, Apr 29, priced at $599 just found
Wed, Apr 22 - Wed, Apr 29
UIO
Quito
SCL
Santiago
$600 Roundtrip, just found
$600
Roundtrip
just found
Select avianca flight, departing Wed, Apr 22 from Quito to Santiago, returning Wed, Apr 29, priced at $600 just found

More About Flying To Santiago from Quito

Route Information for Flights from Quito to Santiago

Origin Airport IATA Code
UIO
Destination Airport IATA Code
SCL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Quito to Santiago

Looking for guaranteed low prices on Quito to Santiago flights? Orbitz is your source and much more. From cutting-edge mobile tools to great deals, Orbitz makes it easy to book your dream vacation.

Frequent Flyers Earn Miles

Earn frequent flyer miles or points on Orbitz flights from Quito to Santiago. When booking your Quito to Santiago flights, have your frequent flyer number on hand and add it where prompted. Your Orbitz account can store your number for future use, meaning you never miss out on your rewards.

Book Orbitz on the Go

With the Orbitz mobile apps for Android and iPhone, you no longer have to be sitting at your desk to book Quito to Santiago flights. With a few easy clicks, you can book your flights, research hotel rooms, and check your flight status and other important flight information.

Easily Plan Your Vacation

Not only does Orbitz offer great prices on flights from Quito to Santiago, but you will also find fantastic deals on hotels, cruises, and vacation activities. Never miss out on that dream trip or waste hours waiting in long lines—you can buy tickets to attraction in advance with Orbitz to guarantee admission to your favorite places.

Best Deals At Your Fingertips

Orbitz combines low prices on Quito to Santiago flights with discounts on quality hotels. Using Orbitz’s Display Matrix, you can see all your options and savings easily. With our low price guarantee, you know you have the best deals at your fingertips.

Frequently asked questions

What is the shortest flight from Quito to Santiago?
With the flight from Quito to Santiago taking a minimum of 3 hours and 9 minutes, there's plenty of time to kick back and enjoy the ride. Order a glass of red and get comfortable in your seat with an engrossing movie or novel.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.