$292 Cheap flight deals from Quito (UIO) to Santiago (SCL)

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This Weekend's Flight Deals from Quito to Santiago

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jun 7 - Thu, Jun 11
UIO
Mariscal Sucre Intl.
SCL
Arturo Merino Benitez
$530 Roundtrip, found 20 hours ago
$530
Roundtrip
found 20 hours ago
Select LATAM Airlines Group flight, departing Sun, Jun 7 from Mariscal Sucre Intl. to Arturo Merino Benitez, returning Thu, Jun 11, priced at $530 found 20 hours ago

Airfares from $292 One Way, $474 Round Trip from Quito to Santiago

Prices starting at $474 for return flights and $292 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 24 - Sun, Sep 27
UIO
Quito
SCL
Santiago
$474 Roundtrip, found 9 hours ago
$474
Roundtrip
found 9 hours ago
Select LATAM Airlines Group flight, departing Thu, Sep 24 from Quito to Santiago, returning Sun, Sep 27, priced at $474 found 9 hours ago
Fri, Jun 26 - Thu, Jul 23
UIO
Quito
SCL
Santiago
$485 Roundtrip, found 4 hours ago
$485
Roundtrip
found 4 hours ago
Select LATAM Airlines Group flight, departing Fri, Jun 26 from Quito to Santiago, returning Thu, Jul 23, priced at $485 found 4 hours ago
Tue, Jul 14 - Mon, Aug 17
UIO
Quito
SCL
Santiago
$487 Roundtrip, found 17 hours ago
$487
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Jul 14 from Quito to Santiago, returning Mon, Aug 17, priced at $487 found 17 hours ago
Sat, Oct 24 - Sun, Dec 13
UIO
Quito
SCL
Santiago
$492 Roundtrip, found 10 hours ago
$492
Roundtrip
found 10 hours ago
Select LATAM Airlines Group flight, departing Sat, Oct 24 from Quito to Santiago, returning Sun, Dec 13, priced at $492 found 10 hours ago
Thu, Jun 25 - Fri, Oct 2
UIO
Quito
SCL
Santiago
$493 Roundtrip, found 1 day ago
$493
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Thu, Jun 25 from Quito to Santiago, returning Fri, Oct 2, priced at $493 found 1 day ago

Santiago economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Capital Bellet
3.0-star property

Hotel Capital Bellet

9.2/10 Wonderful! (1,012 reviews)

Jul 21 - Jul 24

3 night stay

Quito (UIO) to Santiago (SCL)

Avianca • Non-stop • Coach

Santiago (SCL) to Quito (UIO)

LATAM Airlines Group • Non-stop • Coach
Price was $943, price is now $699 per person
$699
per person
found 1 day ago
Ubicación del hotel y limpieza

Reviewed on Nov 16, 2025

ICON Hotel
4.0-star property

ICON Hotel

8.6/10 Excellent! (1,002 reviews)

Jul 21 - Jul 25

4 night stay

Quito (UIO) to Santiago (SCL)

Avianca • Non-stop • Coach

Santiago (SCL) to Quito (UIO)

LATAM Airlines Group • Non-stop • Coach
Price was $1,242, price is now $885 per person
$885
per person
found 1 day ago
Nice Location and nice hotel

Reviewed on Mar 22, 2026

Aubrey Hotel Boutique
3.5-star property

Aubrey Hotel Boutique

9.4/10 Exceptional! (151 reviews)

Jul 21 - Jul 24

3 night stay

Quito (UIO) to Santiago (SCL)

Avianca • Non-stop • Coach

Santiago (SCL) to Quito (UIO)

LATAM Airlines Group • Non-stop • Coach
Price was $972, price is now $761 per person
$761
per person
found 1 day ago
Very friendly and cared for our health and well being during the Covid Pandemic. Helped arrange everything that we needed. They had just opened the hotel back up due to the pandemic shutdown one week prior, so we were the only ones there during our weekday stay. Easy walking access to the old downtown and right next the the funicular that goes up the Cerro San Cristobal hill. I highly recommend this hotel as a place to stay.

Reviewed on Dec 16, 2021

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More About Flying To Santiago from Quito

Route Information for Flights from Quito to Santiago

Origin Airport IATA Code
UIO
Destination Airport IATA Code
SCL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Quito to Santiago

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Frequently asked questions

What is the shortest flight from Quito to Santiago?
With the flight from Quito to Santiago taking a minimum of 3 hours and 9 minutes, there's plenty of time to kick back and enjoy the ride. Order a glass of red and get comfortable in your seat with an engrossing movie or novel.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.