$146 Cheap flight deals from Gainesville (MCO) to Nicholasville (LEX)

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Airfares from $146 One Way, $290 Round Trip from Gainesville to Nicholasville

Prices starting at $290 for return flights and $146 for one-way flights to Nicholasville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 30 - Mon, Oct 5
MCO
Orlando
LEX
Lexington
$290 Roundtrip, found 5 days ago
$290
Roundtrip
found 5 days ago
Select United flight, departing Wed, Sep 30 from Orlando to Lexington, returning Mon, Oct 5, priced at $290 found 5 days ago
Wed, Sep 30 - Mon, Oct 5
MCO
Orlando
LEX
Lexington
$295 Roundtrip, found 5 days ago
$295
Roundtrip
found 5 days ago
Select United flight, departing Wed, Sep 30 from Orlando to Lexington, returning Mon, Oct 5, priced at $295 found 5 days ago
Tue, Aug 18 - Tue, Aug 25
MCO
Orlando
LEX
Lexington
$304 Roundtrip, found 14 hours ago
$304
Roundtrip
found 14 hours ago
Select United flight, departing Tue, Aug 18 from Orlando to Lexington, returning Tue, Aug 25, priced at $304 found 14 hours ago
Wed, Sep 30 - Mon, Oct 5
MCO
Orlando
LEX
Lexington
$306 Roundtrip, found 5 days ago
$306
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Sep 30 from Orlando to Lexington, returning Mon, Oct 5, priced at $306 found 5 days ago
Wed, Sep 30 - Mon, Oct 5
MCO
Orlando
LEX
Lexington
$306 Roundtrip, found 5 days ago
$306
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 30 from Orlando to Lexington, returning Mon, Oct 5, priced at $306 found 5 days ago

Nicholasville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Capital Plaza Hotel
3.0-star property

Capital Plaza Hotel

8/10 Very Good! (1,062 reviews)

Sep 11 - Sep 13

2 night stay

Orlando (MCO) to Lexington (LEX)

American Airlines • Non-stop roundtrip • Coach
Price was $540, price is now $484 per person
$484
per person
found 16 hours ago
If you have literally any other option, take it. You can remodel a building, but you can’t renovate laziness. This place is filthy, the rooms smell like neglect, and the cigarette-infused pillows are a special kind of hospitality. At this point, the “free breakfast” feels less like a perk and more like a dare. I’m half expecting it to be leftovers from last week. Save yourself the disappointment and stay somewhere else.

Reviewed on Jul 24, 2026

The Manchester
4.0-star property

The Manchester

9.6/10 Exceptional! (1,363 reviews)

Sep 11 - Sep 13

2 night stay

Orlando (MCO) to Lexington (LEX)

American Airlines • Non-stop roundtrip • Coach
Price was $844, price is now $794 per person
$794
per person
found 16 hours ago
Very comfortable beds, helpful staff. Overall, great stay and would definitely stay again!

Reviewed on Jul 26, 2026

GuestHouse Lexington
2.5-star property

GuestHouse Lexington

8.4/10 Very Good! (1,626 reviews)

Sep 11 - Sep 13

2 night stay

Orlando (MCO) to Lexington (LEX)

American Airlines • Non-stop roundtrip • Coach
Price was $519, price is now $491 per person
$491
per person
found 16 hours ago

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Nicholasville first class flight packages

Price found within the past 48 hours. Click for updated prices.
21c Museum Hotel Lexington
4.0-star property

21c Museum Hotel Lexington

8.8/10 Excellent! (1,002 reviews)

Sep 11 - Sep 13

2 night stay

Orlando (MCO) to Lexington (LEX)

Delta • Non-stop roundtrip • FirstClass
Price was $1,138, price is now $1,058 per person
$1,058
per person
found 16 hours ago
We love the 21C properties normally and stayed at this location in 2019. It was lovely, a great location in the middle of downtown Lexington, and close to shopping and restaurants. Sadly, the hotel feels worn now. Our first room had a toilet that was leaking on the floor, needing to be pulled and resealed. We were then upgraded to a corner room on the 14th floor which was amazing with great views from two sides of downtown and beyond. However, some of the paint on trim was peeled or nicked, the refrigerator was leaking water, ruining the wood cabinet in which it sat, and the pull rod on a curtain was no longer attached, making it difficult to fully open the curtain. Since the restaurant is closed for renovation, we walked to the Hilton 3 blocks away for breakfast, although they did offer room service at the 21C. We considered using the room service option but the rooms had no menu. The desk and valet were staffed by one person each so there wasn’t always anyone to ask. That said, the valet on the evening shift was helpful and sweet and the person at the night desk quickly resolved our room issue when we called about the toilet. They did have a bar in the lobby in the evening and a coffee urn in the morning. I suggest that they have a cafe with coffee and pastries in the morning as well as drinks at night.

Reviewed on Jul 24, 2026

Origin Lexington a Wyndham Hotel
3.5-star property

Origin Lexington a Wyndham Hotel

9.4/10 Exceptional! (1,021 reviews)

Sep 11 - Sep 13

2 night stay

Orlando (MCO) to Lexington (LEX)

Delta • Non-stop roundtrip • FirstClass
Price was $1,160, price is now $1,100 per person
$1,100
per person
found 16 hours ago
LOVED my stay at the Origin so much, I’ll be returning to stay again for my annual trip to Lex next year. so quiet, clean, and the food downstairs was great :) I also felt very safe in the area.

Reviewed on Jul 26, 2026

Embassy Suites by Hilton Lexington Green
3.5-star property

Embassy Suites by Hilton Lexington Green

9.4/10 Exceptional! (1,013 reviews)

Sep 11 - Sep 13

2 night stay

Orlando (MCO) to Lexington (LEX)

Delta • Non-stop roundtrip • FirstClass
Price was $1,133, price is now $1,078 per person
$1,078
per person
found 16 hours ago

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More About Flying To Nicholasville from Gainesville

Route Information for Flights from Gainesville to Nicholasville

Origin Airport IATA Code
MCO
Destination Airport IATA Code
LEX
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Gainesville to Nicholasville

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

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