
$128 Cheap flight deals from Knoxville (TYS) to Saint Joseph (RFD)
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This Weekend's Flight Deals from Knoxville to Saint Joseph
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $128 One Way, $189 Round Trip from Knoxville to Saint Joseph
Prices starting at $189 for return flights and $128 for one-way flights to Saint Joseph were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Saint Joseph economy flight packages

Fairmont Chicago at Millennium Park
Nov 7 - Nov 9
Knoxville (TYS) to Chicago (ORD)
Reviewed on Sep 21, 2025

Hotel Riu Plaza Chicago
Nov 7 - Nov 9
Knoxville (TYS) to Chicago (ORD)
Reviewed on Sep 2, 2025

Trump International Hotel & Tower Chicago
Nov 7 - Nov 9
Knoxville (TYS) to Chicago (ORD)
Reviewed on Sep 14, 2025
More About Flying To Saint Joseph from Knoxville
Route Information for Flights from Knoxville to Saint Joseph
Origin Airport IATA Code | TYS |
---|---|
Destination Airport IATA Code | RFD |
Distance | 475 mi |
Direct Flight Airlines | American Airlines, Qatar Airways, Air Canada, JAL, Alaska Airlines, Aer Lingus, Avianca, ANA, Lufthansa, Air New Zealand, United Airlines, British Airways |
Earliest Flight Arrival | 11:55AM UTC |
Latest Flight Arrival | 10:55PM UTC |
Knoxville to Saint Joseph
If you are looking online for bargain Knoxville to Saint Joseph flights, Orbitz is your ideal destination. We understand that vacations can be expensive and offer guaranteed low prices on our domestic and international tickets.
Orbitz Uses Cutting-Edge Mobile Tools
Orbitz may offer low cost Knoxville to Saint Joseph flights but this does not mean that we skimp on giving you the latest mobile apps. You don’t have to worry about checking your flight status as we send the info for your flights from Knoxville to Saint Joseph directly to your smartphone.
Fly Cheap and Earn Miles on Your Knoxville to Saint Joseph Flights
Frequent flyer miles and points are great—and even better when you earn them on cheap flights from Knoxville to Saint Joseph. With Orbitz, you can earn miles for your frequent flyer program on qualified flights. Enter your frequent flyer number when you book with us to get rewarded for your flight.
Orbitz Takes the Hassle Out Of Flying
We know that flying can be stressful, particularly if you are traveling with young children. That’s why we make sure you are aware of any changes or delays to your flights from Knoxville to Saint Joseph via your phone or email address. We can even inform family members too.
Orbitz Flights Fit Around Your Lifestyle
Orbitz understands that you don’t necessarily want to fly at 5:00 a.m—and that sometimes you do. This is why we allow you to find the best Knoxville to Saint Joseph flights at the times you want with ease.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.