$145 Cheap flight deals from Buffalo (BUF) to Gatlinburg (TYS)

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Airfares from $145 One Way, $329 Round Trip from Buffalo to Gatlinburg

Prices starting at $329 for return flights and $145 for one-way flights to Gatlinburg were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 17 - Sat, Sep 19
BUF
Buffalo
TYS
Knoxville
$329 Roundtrip, found 3 days ago
$329
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Sep 17 from Buffalo to Knoxville, returning Sat, Sep 19, priced at $329 found 3 days ago
Tue, Sep 1 - Thu, Sep 3
BUF
Buffalo
TYS
Knoxville
$333 Roundtrip, found 6 days ago
$333
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Sep 1 from Buffalo to Knoxville, returning Thu, Sep 3, priced at $333 found 6 days ago
Tue, Sep 1 - Thu, Sep 3
BUF
Buffalo
TYS
Knoxville
$339 Roundtrip, found 6 days ago
$339
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Sep 1 from Buffalo to Knoxville, returning Thu, Sep 3, priced at $339 found 6 days ago
Thu, Sep 17 - Sat, Sep 19
BUF
Buffalo
TYS
Knoxville
$350 Roundtrip, found 3 days ago
$350
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Sep 17 from Buffalo to Knoxville, returning Sat, Sep 19, priced at $350 found 3 days ago
Fri, Sep 18 - Sun, Sep 20
BUF
Buffalo
TYS
Knoxville
$432 Roundtrip, found 2 days ago
$432
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Fri, Sep 18 from Buffalo to Knoxville, returning Sun, Sep 20, priced at $432 found 2 days ago

Gatlinburg economy flight packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Knoxville Papermill
3.0-star property

La Quinta Inn & Suites by Wyndham Knoxville Papermill

9/10 Wonderful! (1,104 reviews)

Sep 11 - Sep 15

4 night stay

Buffalo (BUF) to Knoxville (TYS)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $700, price is now $596 per person
$596
per person
found 1 day ago
The hotel was very nice and looked like it had been recently remodeled with a gray and teal palette. The staff were efficient and friendly. Check-in and check-out took less than 5 minutes each. There were plenty of well-maintained luggage carts available. The room was clean and updated. It did take around 2-3 hours for it to completely cool off and filter out the humidity. There's a large church up on the hill behind the hotel. The church uses the hotel parking lot as a convenience. There was a lot of foot and vehicle traffic because of this, which complicated getting packed up and checked out on Sunday. It's a 4.5 mile straight shot down I-40 West to the Knoxville Convention Center, which was great for making it to & from our event quickly. I would use this hotel again if I ever have to travel to the Knoxville area.

Reviewed on Aug 5, 2026

The Oliver Hotel
3.5-star property

The Oliver Hotel

9.8/10 Exceptional! (834 reviews)

Sep 11 - Sep 15

4 night stay

Buffalo (BUF) to Knoxville (TYS)

Southwest Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,451, price is now $1,112 per person
$1,112
per person
found 1 day ago
Clean rooms helpful and FRIENDLY staff. GREAT location right around the corner from Market Square and a short walk from three top notch performance centers, and shopping.

Reviewed on Aug 3, 2026

Hyatt Place Knoxville Downtown
3.0-star property

Hyatt Place Knoxville Downtown

9.4/10 Exceptional! (1,040 reviews)

Sep 11 - Sep 15

4 night stay

Buffalo (BUF) to Knoxville (TYS)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $771, price is now $668 per person
$668
per person
found 1 day ago

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More About Flying To Gatlinburg from Buffalo

Route Information for Flights from Buffalo to Gatlinburg

Origin Airport IATA Code
BUF
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Gatlinburg

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.