$147 Cheap flight deals from Des Moines (DSM) to Palo Alto (SJC)
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This Weekend's Flight Deals from Des Moines to Palo Alto
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $147 One Way, $286 Round Trip from Des Moines to Palo Alto
Prices starting at $286 for return flights and $147 for one-way flights to Palo Alto were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Palo Alto economy flight packages
Bay Landing San Francisco Airport Hotel
Aug 29 - Sep 2
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on Jul 7, 2025
The Donatello
Aug 29 - Sep 2
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on May 25, 2025
Marriott San Francisco Fisherman's Wharf
Aug 29 - Sep 2
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on Jul 16, 2025
More About Flying To Palo Alto from Des Moines
Route Information for Flights from Des Moines to Palo Alto
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SJC |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Palo Alto
Orbitz is the best place to find guaranteed low prices on Des Moines to Palo Alto flights. Because of our cutting-edge mobile tools and low fares on domestic and international flights, Orbitz is the best starting point for travelers.
Find Cheap Des Moines to Palo Alto Flights
Orbitz offers free mobile apps for iPhone and Android devices—a great way to find fantastic deals on flights from Des Moines to Palo Alto. Not only that, but you can check the status of your flight or even book low cost hotel rooms with the apps or on m.orbitz.com.
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Discount Travel Planning Made Simple
You will have no problems finding budget flights from Des Moines to Palo Alto on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.
Flights from Des Moines
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- Des Moines to New Orleans
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.