
$113 Cheap flight deals from Des Moines (DSM) to Destin (VPS)
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This Weekend's Flight Deals from Des Moines to Destin
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $113 One Way, $254 Round Trip from Des Moines to Destin
Prices starting at $254 for return flights and $113 for one-way flights to Destin were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Destin economy flight packages

Home2 Suites By Hilton Destin
Nov 30 - Dec 5
Des Moines (DSM) to Fort Walton Beach (VPS)
Reviewed on Oct 22, 2025

The Henderson Beach Resort & Spa
Nov 30 - Dec 5
Des Moines (DSM) to Fort Walton Beach (VPS)
Reviewed on Sep 1, 2025

Harborside by Avantstay Expansive Destin Retreat
Nov 30 - Dec 5
Des Moines (DSM) to Fort Walton Beach (VPS)
More About Flying To Destin from Des Moines
Route Information for Flights from Des Moines to Destin
Origin Airport IATA Code | DSM |
|---|---|
Destination Airport IATA Code | VPS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Destin
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Flights from Des Moines
- Des Moines to Houston
- Des Moines to Dallas
- Des Moines to Atlanta
- Des Moines to Phoenix
- Des Moines to Orlando
- Des Moines to Seattle
- Des Moines to Chicago
- Des Moines to Los Angeles
- Des Moines to New York
- Des Moines to Charlotte
- Des Moines to Detroit
- Des Moines to Washington
- Des Moines to London
- Des Moines to New Orleans
- Des Moines to Sacramento
- Des Moines to Toronto
- Des Moines to San Francisco
- Des Moines to Rome
- Des Moines to Paris
- Des Moines to Hartford
Des Moines Airports
Destin Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
