$95 Cheap flight deals from Des Moines (DSM) to Salem (BOS)
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This Weekend's Flight Deals from Des Moines to Salem
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $95 One Way, $300 Round Trip from Des Moines to Salem
Prices starting at $300 for return flights and $95 for one-way flights to Salem were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Salem economy flight packages
The Godfrey Hotel Boston
Apr 9 - Apr 12
Des Moines (DSM) to Boston (BOS)
Boston (BOS) to Des Moines (DSM)
Reviewed on Nov 1, 2025
The Langham, Boston
Apr 9 - Apr 12
Des Moines (DSM) to Boston (BOS)
Boston (BOS) to Des Moines (DSM)
Reviewed on Jan 12, 2026
Omni Parker House
Apr 9 - Apr 12
Des Moines (DSM) to Boston (BOS)
Boston (BOS) to Des Moines (DSM)
Reviewed on Feb 9, 2026
More About Flying To Salem from Des Moines
Route Information for Flights from Des Moines to Salem
Origin Airport IATA Code | DSM |
|---|---|
Destination Airport IATA Code | BOS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Salem
If you are looking to get guaranteed low prices for Des Moines to Salem flights then Orbitz is the place to go. We use cutting edge mobile tools to find the best deals on air tickets and to keep you updated on delays and changes.
Get Package Savings by Booking Flights and Hotels at the Same Time
Using the Orbitz Matrix display, you can see how much you will save on flights from Des Moines to Salem if the discount fare is combined with a hotel. You can also look at hotel reviews, photos and maps of the area, so it will be convenient to make your budget travel plans.
Orbitz for Business Helps Corporations save Money
Orbitz can assist all businesses from the small to major corporations with discounts on flights from Des Moines to Salem. We fine- tune your needs for Des Moines to Salem flights and optimize your plans by assessing your business and coming up with ways for you to save on air tickets.
Using Online Check-In Makes Flying Simple
You can use the Orbitz website to check-in for your flights from Des Moines to Salem. You can also make changes to your schedule or even cancel a flight.
Flights from Des Moines
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Des Moines Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.