$119 Cheap flight deals from Des Moines (DSM) to Myrtle Beach (MYR)

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This Weekend's Flight Deals from Des Moines to Myrtle Beach

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 5 - Mon, Jul 14
DSM
Des Moines Intl.
MYR
Myrtle Beach Intl.
$566 Roundtrip, found 1 day ago
$566
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jul 5 from Des Moines Intl. to Myrtle Beach Intl., returning Mon, Jul 14, priced at $566 found 1 day ago

Airfares from $119 One Way, $237 Round Trip from Des Moines to Myrtle Beach

Prices starting at $237 for return flights and $119 for one-way flights to Myrtle Beach were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Nov 11 - Tue, Nov 18
DSM
Des Moines
MYR
Myrtle Beach
$237 Roundtrip, just found
$237
Roundtrip
just found
Select American Airlines flight, departing Tue, Nov 11 from Des Moines to Myrtle Beach, returning Tue, Nov 18, priced at $237 just found
Tue, Nov 11 - Tue, Nov 18
DSM
Des Moines
MYR
Myrtle Beach
$237 Roundtrip, just found
$237
Roundtrip
just found
Select Delta flight, departing Tue, Nov 11 from Des Moines to Myrtle Beach, returning Tue, Nov 18, priced at $237 just found
Tue, Nov 11 - Tue, Nov 18
DSM
Des Moines
MYR
Myrtle Beach
$240 Roundtrip, just found
$240
Roundtrip
just found
Select American Airlines flight, departing Tue, Nov 11 from Des Moines to Myrtle Beach, returning Tue, Nov 18, priced at $240 just found
Tue, Nov 11 - Tue, Nov 18
DSM
Des Moines
MYR
Myrtle Beach
$242 Roundtrip, just found
$242
Roundtrip
just found
Select Southwest Airlines flight, departing Tue, Nov 11 from Des Moines to Myrtle Beach, returning Tue, Nov 18, priced at $242 just found
Wed, Aug 27 - Wed, Sep 3
DSM
Des Moines
MYR
Myrtle Beach
$246 Roundtrip, found 4 hours ago
$246
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Wed, Aug 27 from Des Moines to Myrtle Beach, returning Wed, Sep 3, priced at $246 found 4 hours ago

Myrtle Beach economy flight packages

Price found within the past 48 hours. Click for updated prices.
Sands Ocean Club Resort
3.0-star property

Sands Ocean Club Resort

7.6/10 Good! (2,188 reviews)

Aug 8 - Aug 11

3 night stay

Des Moines (DSM) to Myrtle Beach (MYR)

American Airlines • Non-stop roundtrip • Coach
per person
just found
My family loved it.very affordable. Little outdated. Parking was a challenge. Butttt. I can’t wait to go back. Only disappointment was we booked 2 rooms and they couldn’t put us in same tower because we booked from a 3rd party. That was our only issue. It was clean staff were polite they really need a loyalty program

Reviewed on Jun 24, 2025

Marina Inn At Grande Dunes
4.5-star property

Marina Inn At Grande Dunes

9.2/10 Wonderful! (1,709 reviews)

Aug 8 - Aug 11

3 night stay

Des Moines (DSM) to Myrtle Beach (MYR)

American Airlines • Non-stop roundtrip • Coach
per person
just found
This place is great for a short or long stay

Reviewed on Dec 15, 2024

Caribbean Resort & Villas
3.0-star property

Caribbean Resort & Villas

7.8/10 Good! (117 reviews)

Aug 8 - Aug 11

3 night stay

Des Moines (DSM) to Myrtle Beach (MYR)

American Airlines • Non-stop roundtrip • Coach
per person
just found
Good hotel. Clean good customer service.

Reviewed on May 29, 2025

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More About Flying To Myrtle Beach from Des Moines

Route Information for Flights from Des Moines to Myrtle Beach

Origin Airport IATA Code
DSM
Destination Airport IATA Code
MYR
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to Myrtle Beach

Find fantastic fares on domestic and international flights that suit your travel requirements and budget needs by heading to Orbitz. Orbitz has your cheap air tickets for flights from Des Moines to Myrtle Beach.

Flights from Des Moines to Myrtle Beach at bargain prices

Budgeting and hidden costs should be the least of your concerns when planning a trip. Your priority should be planning all the things you want to do during your stay. With our low fares on Des Moines to Myrtle Beach flights, you know you are getting the best deal for your vacation or business trip budget—and not incurring hidden costs or paying for over-priced tickets offered by some airlines. We want to help you enjoy your trip the way you deserve.

Remain up-to-date on your flights from Des Moines to Myrtle Beach

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Orbitz booking discounts for Des Moines to Myrtle Beach flights

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Frequently asked questions

What is the shortest flight from Des Moines to Myrtle Beach?
The shortest flight time from Des Moines Intl. Airport (DSM) to Myrtle Beach, SC (MYR-Myrtle Beach Intl.) is 3 hours and 5 minutes. Grab your favorite tipple from the drink trolley, get stuck into your travel journal or get to know your seat mate --- you'll have enough time on this medium-haul journey.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.