
$119 Cheap flight deals from Des Moines (DSM) to Myrtle Beach (MYR)
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This Weekend's Flight Deals from Des Moines to Myrtle Beach
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $119 One Way, $237 Round Trip from Des Moines to Myrtle Beach
Prices starting at $237 for return flights and $119 for one-way flights to Myrtle Beach were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Myrtle Beach economy flight packages

Sands Ocean Club Resort
Aug 8 - Aug 11
Des Moines (DSM) to Myrtle Beach (MYR)
Reviewed on Jun 24, 2025


More About Flying To Myrtle Beach from Des Moines
Route Information for Flights from Des Moines to Myrtle Beach
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | MYR |
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Des Moines to Myrtle Beach
Find fantastic fares on domestic and international flights that suit your travel requirements and budget needs by heading to Orbitz. Orbitz has your cheap air tickets for flights from Des Moines to Myrtle Beach.
Flights from Des Moines to Myrtle Beach at bargain prices
Budgeting and hidden costs should be the least of your concerns when planning a trip. Your priority should be planning all the things you want to do during your stay. With our low fares on Des Moines to Myrtle Beach flights, you know you are getting the best deal for your vacation or business trip budget—and not incurring hidden costs or paying for over-priced tickets offered by some airlines. We want to help you enjoy your trip the way you deserve.
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Orbitz booking discounts for Des Moines to Myrtle Beach flights
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Frequently asked questions
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Flights from Des Moines
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.