$119 Cheap flight deals from Des Moines (DSM) to Upstate South Carolina (GSP)
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This Weekend's Flight Deals from Des Moines to Upstate South Carolina
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $119 One Way, $217 Round Trip from Des Moines to Upstate South Carolina
Prices starting at $217 for return flights and $119 for one-way flights to Upstate South Carolina were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Upstate South Carolina economy flight packages
La Quinta Inn & Suites by Wyndham Greenville Haywood
Oct 1 - Oct 4
Des Moines (DSM) to Greenville (GSP)
Reviewed on May 10, 2025
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Sep 11 - Sep 14
Des Moines (DSM) to Greenville (GSP)
Reviewed on Mar 20, 2025
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Sep 11 - Sep 14
Des Moines (DSM) to Greenville (GSP)
Reviewed on Aug 3, 2025
More About Flying To Upstate South Carolina from Des Moines
Route Information for Flights from Des Moines to Upstate South Carolina
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | GSP |
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Earliest Flight Arrival | |
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Des Moines to Upstate South Carolina
If you are looking to get guaranteed low prices for Des Moines to Upstate South Carolina flights then Orbitz is the place to go. We use cutting edge mobile tools to find the best deals on air tickets and to keep you updated on delays and changes.
Get Package Savings by Booking Flights and Hotels at the Same Time
Using the Orbitz Matrix display, you can see how much you will save on flights from Des Moines to Upstate South Carolina if the discount fare is combined with a hotel. You can also look at hotel reviews, photos and maps of the area, so it will be convenient to make your budget travel plans.
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Using Online Check-In Makes Flying Simple
You can use the Orbitz website to check-in for your flights from Des Moines to Upstate South Carolina. You can also make changes to your schedule or even cancel a flight.
Flights from Des Moines
- Des Moines to Phoenix
- Des Moines to Dallas
- Des Moines to Orlando
- Des Moines to Chicago
- Des Moines to Atlanta
- Des Moines to Los Angeles
- Des Moines to Houston
- Des Moines to Seattle
- Des Moines to New York
- Des Moines to New Orleans
- Des Moines to Detroit
- Des Moines to Charlotte
- Des Moines to Washington
- Des Moines to London
- Des Moines to Toronto
- Des Moines to San Francisco
- Des Moines to Rome
- Des Moines to Sacramento
- Des Moines to San José
- Des Moines to Hartford
Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.