$158 Cheap flight deals from Des Moines (DSM) to San Juan (SJU)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Airfares from $158 One Way, $390 Round Trip from Des Moines to San Juan

Prices starting at $390 for return flights and $158 for one-way flights to San Juan were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Feb 24 - Wed, Feb 25
DSM
Des Moines
SJU
San Juan
$390 Roundtrip, found 2 days ago
$390
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Feb 24 from Des Moines to San Juan, returning Wed, Feb 25, priced at $390 found 2 days ago
Mon, Jan 26 - Fri, Jan 30
DSM
Des Moines
SJU
San Juan
$395 Roundtrip, found 3 days ago
$395
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Mon, Jan 26 from Des Moines to San Juan, returning Fri, Jan 30, priced at $395 found 3 days ago
Sat, Feb 21 - Thu, Feb 26
DSM
Des Moines
SJU
San Juan
$395 Roundtrip, found 2 days ago
$395
Roundtrip
found 2 days ago
Select United flight, departing Sat, Feb 21 from Des Moines to San Juan, returning Thu, Feb 26, priced at $395 found 2 days ago
Sun, Jan 11 - Fri, Jan 16
DSM
Des Moines
SJU
San Juan
$397 Roundtrip, found 4 hours ago
$397
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sun, Jan 11 from Des Moines to San Juan, returning Fri, Jan 16, priced at $397 found 4 hours ago
Sat, Feb 21 - Fri, Feb 27
DSM
Des Moines
SJU
San Juan
$401 Roundtrip, found 2 days ago
$401
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Feb 21 from Des Moines to San Juan, returning Fri, Feb 27, priced at $401 found 2 days ago

San Juan economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Oliver Hotel
3.0-star property

The Oliver Hotel

9/10 Wonderful! (50 reviews)

Jan 5 - Jan 8

3 night stay

Des Moines (DSM) to San Juan (SJU)

American Airlines • Roundtrip • Coach
Price was $1,129, price is now $678 per person
$678
per person
found 1 day ago
Aire de O:live
4.0-star property

Aire de O:live

9/10 Wonderful! (328 reviews)

Jan 5 - Jan 8

3 night stay

Des Moines (DSM) to San Juan (SJU)

American Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $1,461, price is now $962 per person
$962
per person
found 1 day ago
The staff were all fantastic. Very nice people. I wasn't crazy about the room. The windows are like an office building- they don't open. The Wifi was quite spotty. The sliding door for the toilet didnt work. The clothes closet didn't close properly. The bathroom sink was beautiful but the joystick spout was weird. Small complaints, really. But I would really have loved an open window...Great beach!

Reviewed on Apr 9, 2025

Hyatt Regency Grand Reserve Puerto Rico
4.0-star property

Hyatt Regency Grand Reserve Puerto Rico

9/10 Wonderful! (2,764 reviews)

Jan 5 - Jan 8

3 night stay

Des Moines (DSM) to San Juan (SJU)

American Airlines • Roundtrip • Coach
Price was $1,347, price is now $920 per person
$920
per person
found 1 day ago
Great resort with a lot of amenities and for a reasonable price. The location on the island is far enough away from everything to feel secluded but close enough to get into town for shopping or nightlife if desired. I’d go back for sure.

Reviewed on Nov 11, 2025

Don't see what you're looking for?
See all available trips from Des Moines to San Juan
View all trips

More About Flying To San Juan from Des Moines

Route Information for Flights from Des Moines to San Juan

Origin Airport IATA Code
DSM
Destination Airport IATA Code
SJU
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to San Juan

Orbitz gives you great deals on your flights from Des Moines to San Juan. If you also need a discount car rental or a cheap hotel room after you arrived at your destination, Orbitz has you covered.

We Offer Great Travel Deals and Discounts

When you book flights from Des Moines to San Juan with Orbitz for, you can be assured that you are getting the lowest price possible. Orbitz works constantly with our airline partners to ensure guaranteed low prices on Des Moines to San Juan flights for your trip—whether you are traveling for business or for fun with your family.

Enjoy Savings on Last-Minute Flights

If you are looking for a discount price on last-minute flights from Des Moines to San Juan, chances are that Orbitz can offer you a deal that will save you lots of money. Whether you just want to get away for the weekend or go on a vacation lasting weeks, Orbitz can help you find the best deals on Des Moines to San Juan flights that fit your budget and your itinerary for the perfect trip.

Full-Service Mobile Apps

Need more mobility when it comes to travel planning? Orbitz has easy-to-use mobile apps for iPhone, iPad, and Android, to help the traveler on the go. Not only can use the apps to find huge savings on Des Moines to San Juan flights wherever you are, but you can also check out and book discount hotel rooms too. The apps will also keep you up-to-date when it’s time to fly. Get easy access to your itinerary for flights from Des Moines to San Juan and review gate and baggage claim details too.

Frequently asked questions

Am I able to catch a flight from Des Moines to San Juan now?
Head to our Covid-19 Travel Advisor for the most up-to-date information on travel restrictions and quarantine when catching a flight from Des Moines to San Juan.
What is the shortest flight from Des Moines to San Juan?
From Des Moines, the distinctive sights and sounds of San Juan are at least 5 hours and 31 minutes away. Book your favorite seat, or maybe even one with a bit more legroom, and fly to your destination in comfort.
If I am not able to travel due to COVID-19, can I cancel my flight to San Juan?
We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to San Juan have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to San Juan with flexible change policies?
In most cases you'll have the option to reschedule your flight to San Juan without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2020 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data the cheapest month to fly is August. Perfect for those who need a weekend getaway, or just a break from it all before the weather changes. Be aware that the most expensive time to fly is the height of summer, with ticket prices peaking in the month of June.
How can I save money on flights?
To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2020 saved up to 45% on their airfares. Get mixing and matching today!

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.