$258 Cheap flight deals from Panama City (PTY) to Quito (UIO)

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This Weekend's Flight Deals from Panama City to Quito

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 12 - Sun, Sep 13
PTY
Tocumen Intl.
UIO
Mariscal Sucre Intl.
$472 Roundtrip, found 5 days ago
$472
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Sep 12 from Tocumen Intl. to Mariscal Sucre Intl., returning Sun, Sep 13, priced at $472 found 5 days ago

Airfares from $258 One Way, $472 Round Trip from Panama City to Quito

Prices starting at $472 for return flights and $258 for one-way flights to Quito were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 12 - Sun, Sep 13
PTY
Panama City
UIO
Quito
$483 Roundtrip, found 5 days ago
$483
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Sep 12 from Panama City to Quito, returning Sun, Sep 13, priced at $483 found 5 days ago
Sat, Sep 12 - Sun, Sep 13
PTY
Panama City
UIO
Quito
$504 Roundtrip, found 5 days ago
$504
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Sep 12 from Panama City to Quito, returning Sun, Sep 13, priced at $504 found 5 days ago
Sun, Nov 1 - Fri, Nov 6
PTY
Panama City
UIO
Quito
$509 Roundtrip, found 6 days ago
$509
Roundtrip
found 6 days ago
Select avianca flight, departing Sun, Nov 1 from Panama City to Quito, returning Fri, Nov 6, priced at $509 found 6 days ago
Sat, Sep 12 - Sun, Sep 13
PTY
Panama City
UIO
Quito
$523 Roundtrip, found 5 days ago
$523
Roundtrip
found 5 days ago
Select Copa flight, departing Sat, Sep 12 from Panama City to Quito, returning Sun, Sep 13, priced at $523 found 5 days ago
Mon, Nov 2 - Sat, Nov 7
PTY
Panama City
UIO
Quito
$523 Roundtrip, found 6 days ago
$523
Roundtrip
found 6 days ago
Select avianca flight, departing Mon, Nov 2 from Panama City to Quito, returning Sat, Nov 7, priced at $523 found 6 days ago

Quito economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Quito
3.5-star property

Hotel Quito

8.4/10 Very Good! (293 reviews)

Nov 1 - Nov 7

6 night stay

Panama City (PTY) to Quito (UIO)

Copa • Roundtrip • Coach
Price was $939, price is now $693 per person
$693
per person
found 1 day ago

Old Town Quito Suites, Apartments & Boutique hotel
4.0-star property

Old Town Quito Suites, Apartments & Boutique hotel

10/10 Exceptional! (185 reviews)

Nov 1 - Nov 7

6 night stay

Panama City (PTY) to Quito (UIO)

Copa • Roundtrip • Coach
Price was $1,164, price is now $841 per person
$841
per person
found 1 day ago
Fantastic. Its rare that I get surprised by hotel but Old Town customer service, status and design of the rooms really knocked my socks off. The staff was so kind and attentive, I’ve never seen anything like it at this style of hotel. Hats off to the whole team.

Reviewed on Aug 14, 2026

Hotel Dann Carlton Quito
5.0-star property

Hotel Dann Carlton Quito

9.2/10 Wonderful! (1,005 reviews)

Nov 1 - Nov 7

6 night stay

Panama City (PTY) to Quito (UIO)

Copa • Roundtrip • Coach
Price was $1,217, price is now $908 per person
$908
per person
found 1 day ago
A nice hotel in a safe area with multiple restaurants

Reviewed on Sep 6, 2026

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More About Flying To Quito from Panama City

Route Information for Flights from Panama City to Quito

Origin Airport IATA Code
PTY
Destination Airport IATA Code
UIO
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Quito

Orbitz can provide you with the greatest deals on a wide range of Panama City to Quito flights. Orbitz offers guaranteed low prices and offers you the convenience of cutting-edge mobile tools thus providing you with your best travel experience ever.

Mobile Apps for Panama City to Quito Flights

You can use our mobile app to find the cheapest prices for flights from Panama City to Quito. With this cutting-edge technology, you can check up on your flight’s status, gate number and luggage claim handling, and reserve exclusive deals on top hotels at short notice.

Loyalty Rewarded

For travelers who regularly book Panama City to Quito flights, our frequent flyer program offers even more low-cost air tickets. You will be able to store your miles in your personal Orbitz account and add them with ease to your future reservations.

Trouble-Free Traveling With Flight Alerts

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 Budget Flying Made Simple

Finding cheap flights from Panama City to Quito is easy with Orbitz. You can pick and choose airlines for your international flights to create inexpensive yet convenient travel arrangements.

Frequently asked questions

Are there non-stop flights from Panama City to Quito?
Copa Airlines will fly you nonstop from Tocumen Intl. Airport (PTY) to UIO, so you won't have to worry about swapping planes or missing your next flight on this route.
What is the shortest flight from Panama City to Quito?
If the weather is good and all goes as planned, you could be touching down at UIO from Panama City (PTY-Tocumen Intl.) in as little as 1 hour and 47 minutes. With such a brief flight time, consider taking just hand luggage.
What airlines fly from Panama City to Quito most frequently?
Copa Airlines is the most frequent airline operating on the Panama City to Quito route. You can select from 117 flights per month with this carrier.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.