$246 Cheap flight deals from Panama City (PTY) to Quito (UIO)

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This Weekend's Flight Deals from Panama City to Quito

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 31 - Fri, Aug 7
PTY
Tocumen Intl.
UIO
Mariscal Sucre Intl.
$481 Roundtrip, found 2 days ago
$481
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, Jul 31 from Tocumen Intl. to Mariscal Sucre Intl., returning Fri, Aug 7, priced at $481 found 2 days ago

Airfares from $246 One Way, $426 Round Trip from Panama City to Quito

Prices starting at $426 for return flights and $246 for one-way flights to Quito were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jan 25 - Tue, Jan 26
PTY
Panama City
UIO
Quito
$426 Roundtrip, found 1 day ago
$426
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Jan 25 from Panama City to Quito, returning Tue, Jan 26, priced at $426 found 1 day ago
Mon, Jan 25 - Tue, Jan 26
PTY
Panama City
UIO
Quito
$452 Roundtrip, found 1 day ago
$452
Roundtrip
found 1 day ago
Select avianca flight, departing Mon, Jan 25 from Panama City to Quito, returning Tue, Jan 26, priced at $452 found 1 day ago
Mon, Jan 25 - Tue, Jan 26
PTY
Panama City
UIO
Quito
$454 Roundtrip, found 1 day ago
$454
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Jan 25 from Panama City to Quito, returning Tue, Jan 26, priced at $454 found 1 day ago
Mon, Jan 25 - Tue, Jan 26
PTY
Panama City
UIO
Quito
$475 Roundtrip, found 1 day ago
$475
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Jan 25 from Panama City to Quito, returning Tue, Jan 26, priced at $475 found 1 day ago
Fri, Oct 30 - Thu, Nov 5
PTY
Panama City
UIO
Quito
$481 Roundtrip, found 6 hours ago
$481
Roundtrip
found 6 hours ago
Select avianca flight, departing Fri, Oct 30 from Panama City to Quito, returning Thu, Nov 5, priced at $481 found 6 hours ago

Quito economy flight packages

Price found within the past 48 hours. Click for updated prices.
La Casona de la Ronda Boutique Hotel
3.5-star property

La Casona de la Ronda Boutique Hotel

9.6/10 Exceptional! (231 reviews)

Aug 26 - Aug 31

5 night stay

Panama City (PTY) to Quito (UIO)

Copa • Roundtrip • Coach
Price was $904, price is now $635 per person
$635
per person
found 24 hours ago
Great location unless you have a rental car as there is no parking and you cannot drive on the streets where the hotel is located. Great staff and very helpful

Reviewed on Jul 27, 2026

Old Town Quito Suites, Apartments & Boutique hotel
4.0-star property

Old Town Quito Suites, Apartments & Boutique hotel

10/10 Exceptional! (182 reviews)

Aug 26 - Aug 31

5 night stay

Panama City (PTY) to Quito (UIO)

Copa • Roundtrip • Coach
Price was $1,242, price is now $828 per person
$828
per person
found 24 hours ago
The apartment was a nice size one bedroom with all the amenities advertised...The apartment was very clean & well kept...The staff was friendly & helpful in suggesting & setting up tours, restaurants etc...I would definitely recommend Old Town Quito Suites Apartment & would definitely stay there again.

Reviewed on Jul 22, 2026

Hotel Mama Cuchara by Art Hotels Ecuador
4.5-star property

Hotel Mama Cuchara by Art Hotels Ecuador

10/10 Exceptional! (38 reviews)

Aug 26 - Aug 31

5 night stay

Panama City (PTY) to Quito (UIO)

Copa • Roundtrip • Coach
Price was $1,193, price is now $840 per person
$840
per person
found 24 hours ago
Great hotel, awesome staff. Loved the rooftop bar (great service by Dino). Highly recommended.

Reviewed on Jul 14, 2026

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More About Flying To Quito from Panama City

Route Information for Flights from Panama City to Quito

Origin Airport IATA Code
PTY
Destination Airport IATA Code
UIO
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Quito

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Frequently asked questions

Are there non-stop flights from Panama City to Quito?
Copa Airlines will fly you nonstop from Tocumen Intl. Airport (PTY) to UIO, so you won't have to worry about swapping planes or missing your next flight on this route.
What is the shortest flight from Panama City to Quito?
If the weather is good and all goes as planned, you could be touching down at UIO from Panama City (PTY-Tocumen Intl.) in as little as 1 hour and 47 minutes. With such a brief flight time, consider taking just hand luggage.
What airlines fly from Panama City to Quito most frequently?
Copa Airlines is the most frequent airline operating on the Panama City to Quito route. You can select from 117 flights per month with this carrier.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.