$126 Cheap flight deals from St. Louis (STL) to Middlesboro (TYS)
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This Weekend's Flight Deals from St. Louis to Middlesboro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $126 One Way, $277 Round Trip from St. Louis to Middlesboro
Prices starting at $277 for return flights and $126 for one-way flights to Middlesboro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Middlesboro economy flight packages
River Terrace Resort & Convention Center
May 24 - May 27
St. Louis (STL) to Knoxville (TYS)
Knoxville (TYS) to St. Louis (STL)
Reviewed on Jun 20, 2025
River Edge Inn
May 24 - May 27
St. Louis (STL) to Knoxville (TYS)
Knoxville (TYS) to St. Louis (STL)
Reviewed on Nov 9, 2025
More About Flying To Middlesboro from St. Louis
Route Information for Flights from St. Louis to Middlesboro
Origin Airport IATA Code | STL |
|---|---|
Destination Airport IATA Code | TYS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
St. Louis to Middlesboro
Whether you want to book cheap flights from St. Louis to Middlesboro or are looking for the perfect package holiday, Orbitz is your one-stop source. Taking the stress and expense out of travel, Orbitz helps you find the best fares for St. Louis to Middlesboro flights.
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Middlesboro Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.