
$138 Cheap flight deals from Houston (HOU) to La Mesa (SAN)
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This Weekend's Flight Deals from Houston to La Mesa
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $138 One Way, $197 Round Trip from Houston to La Mesa
Prices starting at $197 for return flights and $138 for one-way flights to La Mesa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
La Mesa economy flight packages

InterContinental San Diego by IHG
Nov 6 - Nov 9
Houston (HOU) to San Diego (SAN)
San Diego (SAN) to Houston (HOU)
Reviewed on Aug 14, 2025


Sentral Gaslamp Quarter
Nov 6 - Nov 9
Houston (HOU) to San Diego (SAN)
San Diego (SAN) to Houston (HOU)
Reviewed on Jul 27, 2025
More About Flying To La Mesa from Houston
Route Information for Flights from Houston to La Mesa
Origin Airport IATA Code | HOU |
---|---|
Destination Airport IATA Code | SAN |
Distance | 1300 mi |
Direct Flight Airlines | Emirates, Lufthansa, United Airlines |
Earliest Flight Arrival | 5:53PM UTC |
Latest Flight Arrival | 4:45AM UTC |
Houston to La Mesa
If you are looking online for bargain Houston to La Mesa flights, Orbitz is your ideal destination. We understand that vacations can be expensive and offer guaranteed low prices on our domestic and international tickets.
Orbitz Uses Cutting-Edge Mobile Tools
Orbitz may offer low cost Houston to La Mesa flights but this does not mean that we skimp on giving you the latest mobile apps. You don’t have to worry about checking your flight status as we send the info for your flights from Houston to La Mesa directly to your smartphone.
Fly Cheap and Earn Miles on Your Houston to La Mesa Flights
Frequent flyer miles and points are great—and even better when you earn them on cheap flights from Houston to La Mesa. With Orbitz, you can earn miles for your frequent flyer program on qualified flights. Enter your frequent flyer number when you book with us to get rewarded for your flight.
Orbitz Takes the Hassle Out Of Flying
We know that flying can be stressful, particularly if you are traveling with young children. That’s why we make sure you are aware of any changes or delays to your flights from Houston to La Mesa via your phone or email address. We can even inform family members too.
Orbitz Flights Fit Around Your Lifestyle
Orbitz understands that you don’t necessarily want to fly at 5:00 a.m—and that sometimes you do. This is why we allow you to find the best Houston to La Mesa flights at the times you want with ease.
Flights from Houston
- Houston to New York
- Houston to Chicago
- Houston to Orlando
- Houston to Los Angeles
- Houston to Dallas
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- Houston to Phoenix
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- Houston to Detroit
- Houston to San Francisco
- Houston to Paris
- Houston to Rome
- Houston to Indianapolis
- Houston to Hartford
- Houston to Kansas City
- Houston to Beijing
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- Houston to Taipei
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.