$190 Cheap flight deals from Guayaquil (GYE) to Medellín (MDE)

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This Weekend's Flight Deals from Guayaquil to Medellín

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Oct 4 - Wed, Oct 7
GYE
Jose Joaquin de Olmedo Intl.
MDE
José María Córdova Intl.
$494 Roundtrip, found 10 hours ago
$494
Roundtrip
found 10 hours ago
Select avianca flight, departing Sun, Oct 4 from Jose Joaquin de Olmedo Intl. to José María Córdova Intl., returning Wed, Oct 7, priced at $494 found 10 hours ago

Airfares from $190 One Way, $388 Round Trip from Guayaquil to Medellín

Prices starting at $388 for return flights and $190 for one-way flights to Medellín were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Nov 23 - Tue, Dec 1
GYE
Guayaquil
MDE
Medellín
$388 Roundtrip, found 15 hours ago
$388
Roundtrip
found 15 hours ago
Select LATAM Airlines Group flight, departing Mon, Nov 23 from Guayaquil to Medellín, returning Tue, Dec 1, priced at $388 found 15 hours ago
Thu, Nov 12 - Mon, Nov 16
GYE
Guayaquil
MDE
Medellín
$389 Roundtrip, found 22 hours ago
$389
Roundtrip
found 22 hours ago
Select LATAM Airlines Group flight, departing Thu, Nov 12 from Guayaquil to Medellín, returning Mon, Nov 16, priced at $389 found 22 hours ago
Fri, Nov 6 - Wed, Nov 11
GYE
Guayaquil
MDE
Medellín
$395 Roundtrip, found 6 days ago
$395
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, Nov 6 from Guayaquil to Medellín, returning Wed, Nov 11, priced at $395 found 6 days ago
Fri, Nov 6 - Fri, Nov 13
GYE
Guayaquil
MDE
Medellín
$397 Roundtrip, found 6 days ago
$397
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, Nov 6 from Guayaquil to Medellín, returning Fri, Nov 13, priced at $397 found 6 days ago
Thu, Nov 12 - Sun, Nov 15
GYE
Guayaquil
MDE
Medellín
$403 Roundtrip, found 6 days ago
$403
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Thu, Nov 12 from Guayaquil to Medellín, returning Sun, Nov 15, priced at $403 found 6 days ago

Medellín economy flight packages

Price found within the past 48 hours. Click for updated prices.
Lettera Hotel
3.5-star property

Lettera Hotel

9.6/10 Exceptional! (623 reviews)

Nov 2 - Nov 5

3 night stay

Guayaquil (GYE) to Medellín (MDE)

Avianca • Roundtrip • Coach
Price was $917, price is now $727 per person
$727
per person
found 1 day ago
Our time staying at the Lettera Hotel in Medellín was great. It was a beautiful, well maintained hotel with great staff. Everyone on the property was eager to help and very amicable. The view from our balcony was great, our room was amazing, and overall a perfect experience. The restaurant had great dishes and the bar had a well-stocked variety of local and imported drinks to try. We would certainly stay here again without hesitation.

Reviewed on Sep 28, 2026

Devú
5.0-star property

Devú

9.8/10 Exceptional! (37 reviews)

Nov 2 - Nov 5

3 night stay

Guayaquil (GYE) to Medellín (MDE)

Avianca • Roundtrip • Coach
Price was $1,053, price is now $803 per person
$803
per person
found 1 day ago
Wonderful place, very comfortable, great customer service just don’t get the airport transportation offered as it is more expensive than getting a regular Uber. Location is great and overall fantastic

Reviewed on Sep 27, 2026

The Charlee Hotel
5.0-star property

The Charlee Hotel

8.8/10 Excellent! (1,001 reviews)

Nov 2 - Nov 5

3 night stay

Guayaquil (GYE) to Medellín (MDE)

Avianca • Roundtrip • Coach
Price was $1,081, price is now $826 per person
$826
per person
found 1 day ago
Unexpected fees and disappointing experience I booked The Charlee Hotel through Expedia based on the price and information presented during the booking process. After arriving, I was surprised by a mandatory resort fee and an additional fee for having a visitor, even when the visitor was not staying overnight. I have stayed at many hotels and have never encountered a visitor fee like this. If these are important conditions of staying at the property, they should be clearly disclosed before the reservation is completed. I contacted Expedia about the issue. They told me the resort fee was included somewhere under “Taxes and Fees” or “Due at Property,” while the visitor policy was listed under “Hotel Policies.” However, I believe significant additional charges and restrictions should be clearly communicated upfront. My issue is not simply the money—it’s the lack of transparency. Make sure you carefully review all fees and visitor policies before booking. Based on my experience, I would not stay here again.

Reviewed on Oct 1, 2026

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More About Flying To Medellín from Guayaquil

Route Information for Flights from Guayaquil to Medellín

Origin Airport IATA Code
GYE
Destination Airport IATA Code
MDE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Guayaquil to Medellín

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Frequently asked questions

What is the shortest flight from Guayaquil to Medellin?
The journey from Guayaquil to Medellin can be as quick as 2 hours and 51 minutes. With an easy flight time like this, why not take off on a spontaneous getaway?
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.