Cheap flights from TYS to LFT (McGhee Tyson to Lafayette Regional)
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Cheap Flights from TYS to LFT starting at $254 One Way, $319 Round Trip
Prices starting at $319 for return flights and $254 for one-way flights to Lafayette Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
TYS
Knoxville
LFT
Lafayette
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
TYS
Knoxville
LFT
Lafayette
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
TYS
Knoxville
LFT
Lafayette
$326 Roundtrip, found 1 day ago
$326
Roundtrip
found 1 day ago
TYS
Knoxville
LFT
Lafayette
$354 Roundtrip, found 15 hours ago
$354
Roundtrip
found 15 hours ago
TYS
Knoxville
LFT
Lafayette
$357 Roundtrip, found 15 hours ago
$357
Roundtrip
found 15 hours ago
Hotel Ideas near Lafayette Regional
Airport Hotels near Lafayette Regional
Sonesta ES Suites Lafayette Airport
807 Hugh Wallis Rd S Lafayette LA
$68 nightly
The price is $78 total per night from Jan 18 to Jan 19
$78 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (171 reviews)
The room and property were top notch. Everything you need was available in the room, which was also very neat and tidy. The staff were also very helpful.
Reviewed on Jan 7, 2026
DoubleTree by Hilton Hotel Lafayette
1521 W Pinhook Rd Lafayette LA
$86 nightly
The price is $99 total per night from Jan 25 to Jan 26
$99 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,000 reviews)
Unfortunately, I missed breakfast.
Reviewed on Jan 7, 2026
WoodSpring Suites Lafayette
200 Hugh Wallis Rd Lafayette LA
$65 nightly
The price is $75 total per night from Jan 13 to Jan 14
$75 total
Jan 13 - Jan 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Cajundome and Ostrich ...
6.6/10 (1,002 reviews)
Excellent
Reviewed on Dec 4, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Lafayette
Sonesta ES Suites Lafayette Airport
807 Hugh Wallis Rd S Lafayette LA
$68 nightly
The price is $78 total per night from Jan 18 to Jan 19
$78 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (171 reviews)
The room and property were top notch. Everything you need was available in the room, which was also very neat and tidy. The staff were also very helpful.
Reviewed on Jan 7, 2026
DoubleTree by Hilton Hotel Lafayette
1521 W Pinhook Rd Lafayette LA
$86 nightly
The price is $99 total per night from Jan 25 to Jan 26
$99 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,000 reviews)
Unfortunately, I missed breakfast.
Reviewed on Jan 7, 2026
Comfort Suites Oil Center
114 Rue Fernand Lafayette LA
$79 nightly
The price is $90 total per night from Jan 25 to Jan 26
$90 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Staff was very helpful
Reviewed on Jan 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lafayette Hotels With Airport Transportation
Comfort Suites Oil Center
114 Rue Fernand Lafayette LA
$79 nightly
The price is $90 total per night from Jan 25 to Jan 26
$90 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Staff was very helpful
Reviewed on Jan 8, 2026
Courtyard by Marriott Lafayette Airport
214 E Kaliste Saloom Rd Lafayette LA
$114 nightly
The price is $131 total per night from Jan 25 to Jan 26
$131 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.2/10 Very Good! (996 reviews)
Yes, we enjoyed out stay
Reviewed on Dec 12, 2025
Discovery Inn
120 E Kaliste Saloom Rd Lafayette LA
$53 nightly
The price is $62 total per night from Jan 18 to Jan 19
$62 total
Jan 18 - Jan 19
Total with taxes and fees
Stay at this hotel in Lafayette. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Cajundome and Acadian Village Shopping Center are ...
7.2/10 Good! (681 reviews)
Clean room good AC . Problem was people who apparently live at hotel were a bit sketchy. Vagrants coming through parking lot was unnerving. Not great place for small children.
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Lafayette Hotels
Sonesta ES Suites Lafayette Airport
807 Hugh Wallis Rd S Lafayette LA
$68 nightly
The price is $78 total per night from Jan 18 to Jan 19
$78 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (171 reviews)
The room and property were top notch. Everything you need was available in the room, which was also very neat and tidy. The staff were also very helpful.
Reviewed on Jan 7, 2026
Microtel Inn & Suites by Wyndham Scott/Lafayette
301 Ambassador Caffery Pkwy Scott LA
$60 nightly
The price is $69 total per night from Jan 13 to Jan 14
$69 total
Jan 13 - Jan 14
Total with taxes and fees
Stay at this hotel in Scott. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.6/10 Good! (1,002 reviews)
Breakfast generic, was in a rush before 9 to clean it almost ran into me twice. Felt rushed and the front desk forgot to give me back my credit card.
Reviewed on Jan 6, 2026
Days Inn by Wyndham Lafayette/University
1620 N University Ave Lafayette LA
$59 nightly
The price is $68 total per night from Jan 19 to Jan 20
$68 total
Jan 19 - Jan 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cajundome and Moore Park are ...
BAD experience.
We arrived and there was a construction fence around it. The office was closed with 2 phone numbers on the door to call for service. Called both numbers numerous times, with no answer. All the rooms were gutted and the furniture was outside. Looked like they are in the middle of renovating (hopefully, ...
Reviewed on Nov 15, 2021
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Lafayette
Home2 Suites by Hilton Parc Lafayette
1909 Kaliste Saloom Road Lafayette LA
$128 nightly
The price is $147 total per night from Jan 18 to Jan 19
$147 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (787 reviews)
Would definitely stay they again
Reviewed on Dec 2, 2025
Comfort Suites Oil Center
114 Rue Fernand Lafayette LA
$79 nightly
The price is $90 total per night from Jan 25 to Jan 26
$90 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Staff was very helpful
Reviewed on Jan 8, 2026
Homewood Suites by Hilton Lafayette, LA
201 Kaliste Saloom Road Lafayette LA
$99 nightly
The price is $114 total per night from Jan 23 to Jan 24
$114 total
Jan 23 - Jan 24
Total with taxes and fees
Stay at this hotel in Lafayette. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,000 reviews)
Although the hotel was going through renovation, the room design was spectacular. The courtesy breakfast was above-par. The staff upon checking-in and checking-out were extremely courtesy.
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
TYS to LFT Route Info
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TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
LFT Address & GPS
Address:
200 Terminal Drive
Lafayette LA, 70508
United States
IATA Code:
LFT
Longitude:
-91.99327
Latitude:
30.20851
Time Zone:
America/Chicago
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- Virginia Highlands Airport (VJI)
- DeKalb-Peachtree Airport (PDK)
- Fulton County Airport (FTY)
- Pike County - Hatcher Field Airport (PVL)
- Nashville Intl. Airport (BNA)
- Hartsfield-Jackson Atlanta Intl. Airport (ATL)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.