
$128 Cheap flight deals from Des Moines (DSM) to Santa Clarita (BUR)
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This Weekend's Flight Deals from Des Moines to Santa Clarita
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $128 One Way, $172 Round Trip from Des Moines to Santa Clarita
Prices starting at $172 for return flights and $128 for one-way flights to Santa Clarita were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santa Clarita economy flight packages

The LEEF Hotel
Nov 14 - Nov 18
Des Moines (DSM) to Los Angeles (LAX)
Reviewed on Sep 4, 2025

Fleur Noire Hotel - 21 and Over
Nov 26 - Nov 30
Des Moines (DSM) to Los Angeles (LAX)
Los Angeles (LAX) to Des Moines (DSM)
Reviewed on Sep 25, 2025

Glendale Hotel
Nov 14 - Nov 18
Des Moines (DSM) to Los Angeles (LAX)
Reviewed on Mar 6, 2025
More About Flying To Santa Clarita from Des Moines
Route Information for Flights from Des Moines to Santa Clarita
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | BUR |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Santa Clarita
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Flights from Des Moines
- Des Moines to Houston
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Des Moines Airports
Santa Clarita Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.