$131 Cheap flight deals from Des Moines (DSM) to San Ysidro (SAN)
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This Weekend's Flight Deals from Des Moines to San Ysidro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $131 One Way, $277 Round Trip from Des Moines to San Ysidro
Prices starting at $277 for return flights and $131 for one-way flights to San Ysidro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
San Ysidro economy flight packages
Studio 6 National City, CA - Naval Base San Diego
Jul 17 - Jul 20
Des Moines (DSM) to San Diego (SAN)
Reviewed on Mar 24, 2026
Urban Boutique Hotel
Jul 17 - Jul 20
Des Moines (DSM) to San Diego (SAN)
Reviewed on Jul 28, 2025
Old Town Western Inn & Suites
Jul 17 - Jul 20
Des Moines (DSM) to San Diego (SAN)
Reviewed on Jul 21, 2025
More About Flying To San Ysidro from Des Moines
Route Information for Flights from Des Moines to San Ysidro
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SAN |
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Des Moines to San Ysidro
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Your Perfect San YsidroVacation Package
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Low Price Guarantee
With the best deals and easy searching options, Orbitz make it easy and fun to find cheap Des Moines to San Ysidro flights, a great hotel, or a full vacation package. With Orbitz’s low price guarantee, you always get great discounts on air ticket prices.
Flights from Des Moines
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Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.