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Fri, Jun 5 - Sun, Jun 7
SAT
San Antonio Intl.
MSY
Louis Armstrong New Orleans Intl.
$456 Roundtrip, found 1 day ago
$456
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Jun 5 from San Antonio Intl. to Louis Armstrong New Orleans Intl., returning Sun, Jun 7, priced at $456 found 1 day ago
Mon, Aug 17 - Thu, Aug 20
SAT
San Antonio
MSY
New Orleans
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Aug 17 from San Antonio to New Orleans, returning Thu, Aug 20, priced at $199 found 2 days ago
Mon, Aug 17 - Thu, Aug 20
SAT
San Antonio
MSY
New Orleans
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Aug 17 from San Antonio to New Orleans, returning Thu, Aug 20, priced at $199 found 2 days ago
Mon, Aug 17 - Thu, Aug 20
SAT
San Antonio
MSY
New Orleans
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select United flight, departing Mon, Aug 17 from San Antonio to New Orleans, returning Thu, Aug 20, priced at $199 found 2 days ago
Mon, Aug 17 - Thu, Aug 20
SAT
San Antonio
MSY
New Orleans
$228 Roundtrip, found 2 days ago
$228
Roundtrip
found 2 days ago
Select United flight, departing Mon, Aug 17 from San Antonio to New Orleans, returning Thu, Aug 20, priced at $228 found 2 days ago
Mon, Aug 17 - Thu, Aug 20
SAT
San Antonio
MSY
New Orleans
$229 Roundtrip, found 2 days ago
$229
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Aug 17 from San Antonio to New Orleans, returning Thu, Aug 20, priced at $229 found 2 days ago
Price found within the past 48 hours. Click for updated prices.
Bourbon Orleans Hotel
4.0-star property

Bourbon Orleans Hotel

9.2/10 Wonderful! (4,080 reviews)

Jul 3 - Jul 6

3 night stay

San Antonio (SAT) to New Orleans (MSY)

Southwest Airlines • Non-stop • Coach

New Orleans (MSY) to San Antonio (SAT)

Delta • Non-stop • Coach
Price was $807, price is now $641 per person
$641
per person
found 1 day ago
The hotel is centrally located. Even though my room was maybe 20 feet from Bourbon Street, it was very quiet.

Reviewed on May 5, 2026

Melrose Mansion
4.0-star property

Melrose Mansion

9.2/10 Wonderful! (1,003 reviews)

Jul 3 - Jul 6

3 night stay

San Antonio (SAT) to New Orleans (MSY)

Southwest Airlines • Non-stop • Coach

New Orleans (MSY) to San Antonio (SAT)

Delta • Non-stop • Coach
Price was $1,096, price is now $821 per person
$821
per person
found 1 day ago
It was a pleasure to stay at Melrose. We had late check in (12 am) and the security was very accommodating. Everyone at this property was so welcoming and offered to bring whatever we needed to our suite. Bonus: everything is within walking distance (10-15 min walk). Ubers and Lyfts are always nearby if you’re feeling lazy. I will certainly be back!

Reviewed on Mar 16, 2025

The Harlequin by AvantStay
3.5-star property

The Harlequin by AvantStay

9/10 Wonderful! (65 reviews)

Jul 3 - Jul 6

3 night stay

San Antonio (SAT) to New Orleans (MSY)

Southwest Airlines • Non-stop • Coach

New Orleans (MSY) to San Antonio (SAT)

Delta • Non-stop • Coach
Price was $1,349, price is now $1,080 per person
$1,080
per person
found 1 day ago
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Frequently asked questions

Are there non-stop flights from San Antonio to Biloxi?
Yes, you can jet from SAT to New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) with Southwest Airlines, the only airline with nonstop services on this route.
What is the shortest flight from San Antonio to Biloxi?
It can take just 2 hours to get from San Antonio Intl. Airport (SAT) to New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.). Buckle up and enjoy the journey, because you'll be stepping off the plane in a flash.
What airlines fly from San Antonio to Biloxi most frequently?
Book your San Antonio to Biloxi journey with a Southwest Airlines flight. With 8 each month, this airline offers the most flights between these two destinations.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.