
$142 Cheap flight deals from New York (NYC) to Middlesboro (TYS)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from New York to Middlesboro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $142 One Way, $203 Round Trip from New York to Middlesboro
Prices starting at $203 for return flights and $142 for one-way flights to Middlesboro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Middlesboro economy flight packages


Margaritaville Island Hotel
Feb 27 - Mar 1
New York (JFK) to Knoxville (TYS)
Reviewed on Jun 16, 2025

The Historic Gatlinburg Inn
Mar 4 - Mar 8
New York (NYC) to Knoxville (TYS)
Knoxville (TYS) to New York (NYC)
Reviewed on Jan 11, 2026
More About Flying To Middlesboro from New York
Route Information for Flights from New York to Middlesboro
Origin Airport IATA Code | NYC |
|---|---|
Destination Airport IATA Code | TYS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
New York to Middlesboro
Trip-Planning Made Easy
Your search engine may give you thousands of pages of results when you search for cheap flights from New York to Middlesboro, but you can save yourself a lot of hassle and money by going straight to Orbitz.com. Not only do we offer great deals on New York to Middlesboro flights, but we make it easy to book hotels, car rentals, cruises, or a complete vacation package of your dreams.
Discount New York to Middlesboro Flights
Orbitz’s low price guarantee means you get the best fares around. Find the lowest prices for international and domestic tickets and for flights from New York to Middlesboro when you use Orbitz. It’s easy to add activities to your booking, so you can take advantage of all that Middlesboro has to offer.
Easily Book, Change, Cancel Flights From New York to Middlesboro
Orbitz now offers free mobile device apps, so even the busiest multi-taskers can plan their vacations while away from their desktop computer. Plus, instant alerts to your email or mobile phone help you stay on top of any delays or travel updates, so you avoid unpleasant surprises before boarding your New York to Middlesboro flights. Our Customer Service representatives are ready to assist you if you need to change your air travel plans.
Take Advantage of Frequent Flyer Options Through Orbitz
With Orbitz, you do not have to choose between a low fare and earning frequent flyer miles. Simply provide your frequent flyer information when you book your New York to Middlesboro flights.
Flights from New York
- New York to Orlando
- New York to Atlanta
- New York to Paris
- New York to Chicago
- New York to Los Angeles
- New York to Houston
- New York to Toronto
- New York to Dallas
- New York to San Francisco
- New York to Rome
- New York to New Orleans
- New York to Detroit
- New York to Montreal
- New York to Washington
- New York to Kansas City
- New York to Berlin
- New York to Buenos Aires
- New York to Stockholm
- New York to Edmonton
- New York to Sao Paulo
Middlesboro Airports
More Destinations
- Flights from Shanghai to Slade
- Flights from Duluth to Williamsburg
- Flights from Florence to Williamsburg
- Flights from Flint to Williamsburg
- Flights from Grand Junction to Williamsburg
- Flights from Killeen to Williamsburg
- Flights from Austin to Williamsburg
- Flights from Baltimore to Williamsburg
- Flights from Calgary to Williamsburg
- Flights from Dallas to Williamsburg
- Flights from Denver to Williamsburg
- Flights from Detroit to Williamsburg
- Flights from Lisbon District to Williamsburg
- Flights from Minneapolis - St. Paul to Williamsburg
- Flights from Phoenix to Williamsburg
- Flights from Salt Lake City to Williamsburg
- Flights from San Antonio to Williamsburg
- Flights from San Francisco to Williamsburg
- Flights from Vancouver to Williamsburg
- Flights from Washington to Williamsburg
- Flights from Venice to Williamsburg
- Flights from Charleston to Williamsburg
- Flights from Delhi to Williamsburg
- Flights from Shanghai to Williamsburg
- Flights from New Haven to Williamsburg
- Flights from Sacramento to Williamsburg
- Flights from Palm Springs to Williamsburg
- Flights from Lewiston to Williamsburg
- Flights from Montrose to Williamsburg
- Flights from Omaha to Williamsburg
- Flights from Albany to Williamsburg
- Flights from Eureka to Williamsburg
- Flights from Roanoke to Williamsburg
- Flights from St. George to Williamsburg
- Flights from Myrtle Beach to Williamsburg
- Flights from Pittsburgh to Williamsburg
- Flights from Toledo to Williamsburg
- Flights from Tulsa to Williamsburg
- Flights from Brunswick to Williamsburg
- Flights from Albuquerque to Williamsburg
- Flights from Buffalo to Williamsburg
- Flights from Medford to Williamsburg
- Flights from Little Rock to Williamsburg
- Flights from Oklahoma City to Williamsburg
- Flights from Allentown to Williamsburg
- Flights from Boise to Williamsburg
- Flights from Louisville to Williamsburg
- Flights from Binghamton to Williamsburg
- Flights from Asheville to Williamsburg
- Flights from Fayetteville to Williamsburg
- Flights from Cheyenne to Williamsburg
- Flights from Virginia to Williamsburg
- Flights from Corpus Christi to Williamsburg
- Flights from Austin to Richmond
- Flights from Minneapolis - St. Paul to Richmond
- Flights from Sydney to Richmond
- Flights from Washington to Richmond
- Flights from St. George to Richmond
- Flights from Brunswick to Richmond
- Flights from Cedar Rapids - Iowa City to Richmond
- Flights from Fresno to Richmond
- Flights from Louisville to Richmond
- Flights from Baton Rouge to Richmond
- Flights from Grand Rapids to Richmond
- Flights from Albany to Richmond
- Flights from Binghamton to Richmond
- Flights from Bangor to Richmond
- Flights from Tampico to Richmond
- Flights from Hyderabad to Richmond
- Flights from Guatemala City to Richmond
- Flights from Ithaca to Richmond
- Flights from Newport News to Richmond
- Flights from Bismarck to Richmond
- Flights from Bozeman to Richmond
- Flights from St. Petersburg - Clearwater to Berea
- Flights from Dresden to Lake Cumberland
- Flights from Detroit to Pikeville
- Flights from New York to General Burnside State Park
- Flights from Houston to London
- Flights from London to London
- Flights from Minneapolis - St. Paul to London
- Flights from Nashville to London
- Flights from Seoul to London
- Flights from Frankfurt to London
- Flights from Delhi to London
- Flights from New Haven to London
- Flights from Panama City to London
- Flights from Birmingham to London
- Flights from Cape Town to London
- Flights from Tallahassee to London
- Flights from Mumbai to London
- Flights from Bangor to London
- Flights from San Salvador to London
- Flights from Wichita to London
- Flights from Covington to London
- Flights from Sioux Falls to London
- Flights from Rabat to London
- Flights from Hiroshima to London
- Flights from Lubbock to London
- Flights from Bozeman to London
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

